Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bindu Nambiar"'
Autor:
Sirkka Kyostio-Moore, Patricia Berthelette, Susan Piraino, Cathleen Sookdeo, Bindu Nambiar, Robert Jackson, Brenda Burnham, Catherine R O'Riordan, Seng H Cheng, Donna Armentano
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Recombinant adeno-associated viral (rAAV) vectors containing oversized genomes provide transgene expression despite low efficiency packaging of complete genomes. Here, we characterized the properties of oversized rAAV2/8 vectors (up to 5.4 kb) encodi
Externí odkaz:
https://doaj.org/article/dc83fa3e7b174a09885970c39aa9a954
Autor:
Bindu Nambiar, Kartikeya Bolar
Publikováno v:
Journal of Financial Services Marketing. 28:58-73
It can seem paradoxical that someone who evades the use of a debit card still wants access to cash and is willing to use their mobile device at an ATM. The cardless cash technology delivers a solution that is an improvement over the traditional form
Publikováno v:
Cell and Gene Therapy Insights. 5:1461-1471
Autor:
Sirkka Kyostio-Moore, Patricia Berthelette, Bindu Nambiar, Cathleen S. Cornell, Monica Dias Figueiredo
Publikováno v:
American journal of veterinary research. 79(5)
OBJECTIVE To evaluate gene transfer of recombinant adeno-associated viral (rAAV) vectors with AAV2 or AAV5 capsid and encoding hyaluronic acid (HA) synthase-2 (HAS2) into joints of healthy dogs. ANIMALS 22 purpose-bred Beagles. PROCEDURES Plasmid exp
Autor:
Patricia Berthelette, Bindu Nambiar, Donna Armentano, Cathleen Sookdeo, Brenda Burnham, Susan Piraino, Sirkka Kyostio-Moore, Shelley Nass, Karen A. Vincent, Seng H. Cheng, Catherine R. O'Riordan, David W. Souza, Robert B. Jackson
Publikováno v:
Human gene therapy methods. 28(1)
Several ongoing clinical studies are evaluating recombinant adeno-associated virus (rAAV) vectors as gene delivery vehicles for a variety of diseases. However, the production of vectors with genomes >4.7 kb is challenging, with vector preparations fr
Autor:
Sirkka Kyostio-Moore, Susan Piraino, Patricia Berthelette, Bindu Nambiar, Cathleen Sookdeo, Seng H. Cheng, Armentano Donna, Catherine R. O'Riordan, Brenda Burnham, Robert B. Jackson
Publikováno v:
Molecular Therapy. 23
Severe hemophilia A patients with 4 years and consequent reduction or elimination of the need for frequent factor infusions. Similar rAAV-mediated gene transfer for hemophilia A patients is challenging due to the size of the FVIII cDNA that when comb
Autor:
Donna Armentano, Sirkka Kyostio-Moore, Catherine R. O'Riordan, Robert B. Jackson, Cathleen Sookdeo, Seng H. Cheng, David W. Souza, Shelley Nass, Karen A. Vincent, Brenda Burnham, Patricia Berthelette, Bindu Nambiar
Publikováno v:
Molecular Therapy. 24:S40
Recombinant adeno-associated virus (rAAV) vectors are being evaluated as gene delivery vehicles in several clinical trials. The 4.7 kb wild-type (WT) size genome of AAV presents a challenge for incorporating larger transgenes with incomplete vector g
Autor:
Susan Piraino, Robert Jackson, Seng H. Cheng, Donna Armentano, Brenda Burnham, Sirkka Kyostio-Moore, Catherine R. O'Riordan, Cathleen Sookdeo, Patricia Berthelette, Bindu Nambiar
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Recombinant adeno-associated viral (rAAV) vectors containing oversized genomes provide transgene expression despite low efficiency packaging of complete genomes. Here, we characterized the properties of oversized rAAV2/8 vectors (up to 5.4 kb) encodi
Autor:
Sirkka, Kyostio-Moore, Bindu, Nambiar, Elizabeth, Hutto, Patty J, Ewing, Susan, Piraino, Patricia, Berthelette, Cathleen, Sookdeo, Gloria, Matthews, Donna, Armentano
Publikováno v:
Comparative medicine. 61(4)
Osteoarthritis is a common joint disease that currently lacks disease-modifying treatments. Development of therapeutic agents for osteoarthritis requires better understanding of the disease and cost-effective in vivo models that mimic the human disea
Autor:
Dinesh S. Bangari, Elizabeth Hutto, Gloria Matthews, Cathleen Sookdeo, D Armentano, Abraham Scaria, Patty Ewing, Jennifer Sullivan, Sirkka Kyostio-Moore, Patricia Berthelette, N. Moran, Bindu Nambiar
Publikováno v:
Osteoarthritis and Cartilage. (2):358-367
Summary Objective To evaluate the role of synovial oxidative stress on joint pathology in a spontaneous mouse model of osteoarthritis (OA) by intra-articular (IA) delivery of recombinant adeno-associated virus (rAAV) expressing anti-oxidant protein h