Výsledky vyhledávání - "Bindiya, Thakkar"

Pharmacotherapy of type 2 diabetes: An update

Autor: Jagriti Upadhyay, Kyung Hee Park, Stergios A. Polyzos, Eun Seok Kang, Jochen Seufert, Patricia Underwood, Nikolaos Perakakis, Bindiya Thakkar, Niki Katsiki, Elliot Sternthal, Asterios Karagiannis, Christos S. Mantzoros, Stavroula A Paschou

Publikováno v: Metabolism. 78:13-42

Type 2 diabetes (T2DM) is a leading cause of morbidity and mortality worldwide and a major economic burden. The prevalence of T2DM is rising, suggesting more effective prevention and treatment strategies are necessary. The aim of this narrative revie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60da8efd73f4782c0123e5d8a9a60995
https://doi.org/10.1016/j.metabol.2017.08.010

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Omentin-1 levels are reduced by pharmacologic doses of leptin, but remain unaffected by energy deprivation and display no day–night variation

Autor: Christos S. Mantzoros, Konstantinos N. Aronis, Ole-Petter R. Hamnvik, Benjamin E. Schneider, Bindiya Thakkar, John P. Chamberland

Publikováno v: International journal of obesity (2005)

Objective To study the day-night variation of omentin-1 levels and assess whether leptin, and/or short-and long-term energy deprivation alter circulating omentin-1 levels via cytokines. Design and Methods Omentin-1 levels were measured hourly in seru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23631417ffa06ed130e486cd89f46ebc
https://doi.org/10.1038/ijo.2014.106

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Gender Dimorphism and Lack of Day/Night Variation or Effects of Energy Deprivation on Undercarboxylated Osteocalcin Levels in Humans

Autor: Christos S. Mantzoros, Ole-Petter R. Hamnvik, Lesya Zaichenko, Mary Brinkoetter, John P. Chamberland, Joo-Pin Foo, Bindiya Thakkar, Konstantinos N. Aronis

Publikováno v: Obesity. 21:E527-E532

Objective Undercarboxylated osteocalcin (ucOC) is a bone marker with potent metabolic effects. Leptin regulates Esp gene expression and osteocalcin carboxylation in animal models. We aim to elucidate day/night patterns of ucOC levels, whether short-t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8d3c4eef86b484d4b401b09d69d7d18
https://doi.org/10.1002/oby.20453

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Posttraumatic stress disorder, alone or additively with early life adversity, is associated with obesity and cardiometabolic risk

Autor: Michael A. Tsoukas, Kyoung Eun Joung, Cynthia Davis, Nicole Usher, Christos S. Mantzoros, Lesya Zaichenko, Olivia M. Farr, Bindiya Thakkar, Judith A. Crowell, Byung Joon Ko

Publikováno v: Nutrition, metabolism, and cardiovascular diseases : NMCD. 25(5)

Background and aims There is some evidence that posttraumatic stress disorder (PTSD) and early life adversity may influence metabolic outcomes such as obesity, diabetes, and cardiovascular disease. However, whether and how these interact is not clear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8713d134e730c9f0c608fef87cdf06f
https://pubmed.ncbi.nlm.nih.gov/25770759

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Early life adversity is associated with elevated levels of circulating leptin, irisin, and decreased levels of adiponectin in midlife adults

Autor: Kyoung Eun Joung, Kyung Hee Park, Nicole Usher, Judith A. Crowell, Christos S. Mantzoros, Ayse Sahin-Efe, Dorothy E. Warner, Mary Brinkoetter, Cynthia Davis, Lesya Zaichenko, Bindiya Thakkar

Publikováno v: The Journal of clinical endocrinology and metabolism. 99(6)

Early-life adversity, defined as physical, emotional, or sexual abuse and neglect before 18 years of age, is associated with metabolic syndrome, obesity, and type 2 diabetes mellitus in adult life. However, the underlying mechanism is not fully under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3bd0273406aec23126593dca5c2e3e6
https://pubmed.ncbi.nlm.nih.gov/24650014

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Circulating fetuin-A levels are not affected by short and long-term energy deprivation and/or by leptin administration

Autor: Bindiya Thakkar, Janice J. Hwang, John P. Chamberland, Christos S. Mantzoros

Publikováno v: Metabolism: clinical and experimental. 63(6)

Objective Fetuin-A may mediate cross-talk between the liver and adipose tissue. We studied the physiologic regulation of fetuin-A and explored its potential regulation by leptin. Design and Methods Fetuin-A levels were measured in three interventiona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::addd4b49152676fa0d4fb7dabedd42d3
https://pubmed.ncbi.nlm.nih.gov/24703486

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Circulating Irisin in Relation to Insulin Resistance and the Metabolic Syndrome

Autor: Eleni Geladari, Kyung Hee Park, Kyoung Eun Joung, Judith A. Crowell, Fadime Dincer, Ayse Sahin-Efe, Cynthia Davis, Mary Brinkoetter, Lesya Zaichenko, Michael A. Tsoukas, Bindiya Thakkar, Christos S. Mantzoros, Joo Young Huh

Context: Irisin, a recently identified hormone, has been proposed to regulate energy homeostasis and obesity in mice. Whether irisin levels are associated with risk of the metabolic syndrome (MetS), cardiometabolic variables, and cardiovascular disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87387453f2020020636a731b1d41d4eb
https://europepmc.org/articles/PMC3849667/

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Metformin and sulfonylureas in relation to cancer risk in type II diabetes patients: a meta-analysis using primary data of published studies

Autor: Maria Vamvini, Konstantinos N. Aronis, Bindiya Thakkar, Kelsey Shields, Christos S. Mantzoros

Publikováno v: Metabolism: clinical and experimental. 62(7)

Introduction Accumulating evidence suggests that patients with type 2 diabetes mellitus (T2DM) and hyperinsulinemia are at increased risk for developing malignancies. It remains to be fully elucidated whether use of metformin, an insulin sensitizer,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7497f2eac87a947c864e3870d13c678
https://pubmed.ncbi.nlm.nih.gov/23419783

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Gender dimorphism and lack of day/night variation or effects of energy deprivation on undercarboxylated osteocalcin levels in humans

Autor: Joo-Pin, Foo, Konstantinos N, Aronis, John P, Chamberland, Bindiya, Thakkar, Ole-Petter, Hamnvik, Mary, Brinkoetter, Lesya, Zaichenko, Christos S, Mantzoros

Publikováno v: Obesity (Silver Spring, Md.). 21(12)

Undercarboxylated osteocalcin (ucOC) is a bone marker with potent metabolic effects. Leptin regulates Esp gene expression and osteocalcin carboxylation in animal models. We aim to elucidate day/night patterns of ucOC levels, whether short-term and/or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cdedb6642a05cc67636086c2f777bec0
https://pubmed.ncbi.nlm.nih.gov/23512912

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Akademický článek

The Relationship between Metformin Consumption and Cancer Risk: An Updated Umbrella Review of Systematic Reviews and Meta-Analyses.

Autor: Najafi, Farid^1,2, Rajati, Fatemeh^1,2, Sarokhani, Diana², Bavandpour, Maryam², Moradinazar, Mehdi^1,2 M.moradinazar@gmail.com

Publikováno v: International Journal of Preventive Medicine. Jul2023, Vol. 14 Issue 1, p1-S1. 15p.

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