Zobrazeno 1 - 10
of 344
pro vyhledávání: '"Binding (Molecular Function)"'
Autor:
Domin, Gesine, Findeiß, Sven, Wachsmuth, Manja, Will, Sebastian, Stadler, Peter F., Mörl, Mario
Publikováno v:
Nucleic Acids Research, 2016 doi: 10.1093/nar/gkw1267
Riboswitches have gained attention as tools for synthetic biology, since they enable researchers to reprogram cells to sense and respond to exogenous molecules. In vitro evolutionary approaches produced numerous RNA aptamers that bind such small liga
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A15259
https://ul.qucosa.de/api/qucosa%3A15259/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A15259/attachment/ATT-0/
Autor:
Sanjay Pandanaboyana
Publikováno v:
The British Journal of Surgery
The pathogenesis of SARS-CoV-2 infection depends on the ability of the virus to bind to the angiotensin-converting enzyme 2 (ACE2) receptor-primed cellular transmembrane serine protease 2 (TMPRSS2) receptor to facilitate entry into cells.
Autor:
Laura Pritchard-Jones
Publikováno v:
Medical Law Review. 29:143-156
In A Local Authority v JB and A Local Authority v AW, the Court of Appeal and Court of Protection, respectively, had to consider questions regarding decision-making about sexual relationships. This case commentary suggests that both decisions are to
Autor:
Pamelyn Woo, Michael Quezada, Yoon Seok Kim, Michelle Monje, Anna Geraghty, James Reed, Shawn M. Gillespie
Publikováno v:
Neuro Oncol
High-grade gliomas, including diffuse intrinsic pontine glioma, are lethal cancers whose progression is strongly regulated by neuronal activity. One way in which gliomas detect neuronal activity is via interaction with the ectodomain of post-synaptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c898dd1e3eeafda6c8f5f250b4acc57d
https://europepmc.org/articles/PMC8598778/
https://europepmc.org/articles/PMC8598778/
Autor:
Premila Kadamban, Mohammad Tariq
Publikováno v:
Rheumatology Advances in Practice. 5
Case report - Introduction Uveitis is characterised by inflammation of the uvea, which is the middle portion of the eye; the anterior portion of the uvea includes the iris and ciliary body, and the posterior portion of the uvea is known as the choroi
Publikováno v:
Rheumatology Advances in Practice. 5
Case report - Introduction Antiphospholipid syndrome (APS), also known as Hughes syndrome, was first reported by Dr. Graham Hughes in 1983. It can be primary or secondary, with the latter associated with underlying rheumatological conditions. APS is
Publikováno v:
European Heart Journal. 42
Introduction Three dimensional (3D) electroanatomical maps (EAMs) created during electrophysiology procedures are traditionally displayed on 2D monitors connected to mapping systems. This has limitations, such as the lack of interaction with EAMs, th
Autor:
Ai Yamamoto
Publikováno v:
The Journal of Cell Biology
Nthiga et al. identify CALCOCO1 as a receptor for autophagic degradation of Golgi during nutrient starvation. CALCOCO1 binds the Golgi-resident palmitoyltransferase ZDHHC17 and ATG8 family proteins to facilitate Golgiphagy to control Golgi size. Depl
Autor:
Trond Lamark, Thaddaeus Mutugi Nthiga, Birendra Kumar Shrestha, Terje Johansen, Kenneth Bowitz Larsen, Jack-Ansgar Bruun
Publikováno v:
The Journal of Cell Biology
Yamamoto highlights work from Nthiga et al. that shows that Calcoco1 binds Golgi-resident ZDHHC17 to facilitate autophagic degradation of the Golgi.
Degradation by macroautophagy can be highly selective, but given the promiscuity of cargo recept
Degradation by macroautophagy can be highly selective, but given the promiscuity of cargo recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aea35c105fa5f3954ddc53fb4b71d54
https://hdl.handle.net/10037/24220
https://hdl.handle.net/10037/24220
Autor:
Darya Deen, Jan Frayne, Matthias Mann, Daniel C. J. Ferguson, Helena Ayyub, Vasiliki Samara, Michelle L. Holland, Falk Butter, Jacqueline A. Sloane-Stanley, Douglas Vernimmen, Ivan Ferrer-Vicens, David Garrick, Deborah E. Daniels
Publikováno v:
Deen, D, Butter, F, Daniels, D, Ferrer-Vicens, I, Vernimmen, D, Garrick, D, Holland, M L, Samara, V, Sloane-Stanley, J A, Ayyub, H, Mann, M, Frayne, J & Ferguson, D 2021, ' Identification of the transcription factor MAZ as a regulator of erythropoiesis ', Blood Advances, pp. 3002-3015 . https://doi.org/10.1182/bloodadvances.2021004609
Deen, D, Daniels, D E, Ferrer-Vicens, I, Ferguson, D C J, Frayne, J, Vernimmen, D & al., E 2021, ' Identification of the transcription factor MAZ as a regulator of erythropoiesis ', Blood Advances, vol. 5, no. 15, pp. 3002-3015 . https://doi.org/10.1182/bloodadvances.2021004609
Deen, D, Daniels, D E, Ferrer-Vicens, I, Ferguson, D C J, Frayne, J, Vernimmen, D & al., E 2021, ' Identification of the transcription factor MAZ as a regulator of erythropoiesis ', Blood Advances, vol. 5, no. 15, pp. 3002-3015 . https://doi.org/10.1182/bloodadvances.2021004609
Erythropoiesis requires a combination of ubiquitous and tissue-specific transcription factors (TFs). Here, through DNA affinity purification followed by mass spectrometry, we have identified the widely expressed protein MAZ (Myc-associated zinc finge