Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bindhu Gururajan"'
Publikováno v:
International Journal of Pharmaceutics. 559:156-172
Roller compaction is the main technique employed in dry granulation. Ribbon sticking and splitting are among the major factors that can hinder the use of this process for some formulations. Ribbon splitting can occur either transversally (through the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b66a637bf23335dfe4a5a864b7ae45
https://doi.org/10.1016/j.ijpharm.2019.01.031
https://doi.org/10.1016/j.ijpharm.2019.01.031
Autor:
Michael J. Hounslow, Gavin K. Reynolds, Ei L. Chan, Bindhu Gururajan, Agba D. Salman, Kimiaki Washino
Publikováno v:
Powder Technology. 300:92-106
In high shear granulation, the rotating impeller blades impart forces on the granules which are subsequently transmitted throughout the bed through inter-granule collisions. These affect the granule growth behaviour in several ways — the granules c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8c18dd0be40da793b32155bc93f7af7
https://doi.org/10.1016/j.powtec.2016.02.010
https://doi.org/10.1016/j.powtec.2016.02.010
Publikováno v:
Industrial & Engineering Chemistry Research. 52:12408-12419
Roller compaction (RC) is a continuous process for solid dosage form manufacturing within the pharmaceutical industry achieving similar goals as wet granulation while avoiding liquid exposure. From ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f757c77497545c477b82e041249ce83
https://doi.org/10.1021/ie303580y
https://doi.org/10.1021/ie303580y
Autor:
Gavin K. Reynolds, Shen Yu, Chuan-Yu Wu, Bindhu Gururajan, Michael Adams, Ronald John Roberts
Publikováno v:
Chemical Engineering Science. 86:9-18
Lubricants are commonly used in the pharmaceutical industry to prevent adhesion and improve the efficiency of roll compaction and tabletting. The aim of the current work is to develop an improved understanding of the mechanisms involved. Two commonly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c768e49abddb5497d0190050f0cf59b
https://doi.org/10.1016/j.ces.2012.02.026
https://doi.org/10.1016/j.ces.2012.02.026
Publikováno v:
Chemical Engineering Science. 86:38-49
For high shear granulators, the rotating impeller blades exert forces on the granules, which are subsequently transmitted throughout the granule bed through inter-granule collisions. The effect of these collisional stresses on the granule growth beha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43b182021b30c31cf8f924016392cb49
https://doi.org/10.1016/j.ces.2012.04.019
https://doi.org/10.1016/j.ces.2012.04.019
Publikováno v:
Chemical Engineering & Technology. 35:1435-1447
The behavior of dry, steady-state granule beds in each identified flow regime, i.e., frictional, toroidal, and fluidized, in a vertical-axis cylindrical high-shear granulator is studied. The granule bed behavior is discussed in terms of the blade-gra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eb77b7134d9a561d7b6b3a6550c186f
https://doi.org/10.1002/ceat.201200065
https://doi.org/10.1002/ceat.201200065
Publikováno v:
Computers & Chemical Engineering. 34:1049-1057
Very limited work has been reported on comparing the performance of the roller compaction process at different scales. The majority of the approaches highlighted in the literature discuss the applicability of using confined uniaxial compaction for pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b34aa5909e4a932851cab87bf8c61175
https://doi.org/10.1016/j.compchemeng.2010.03.004
https://doi.org/10.1016/j.compchemeng.2010.03.004
Publikováno v:
International Journal of Pharmaceutics. 391:90-97
The compression behaviour of powders during roller compaction is dominated by a number of factors, such as process conditions (roll speed, roll gap, feeding mechanisms and feeding speed) and powder properties (particle size, shape, moisture content).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787af11ace8e20d3ac8890a634c34b66
https://doi.org/10.1016/j.ijpharm.2010.02.022
https://doi.org/10.1016/j.ijpharm.2010.02.022
Autor:
Shen Yu, Joseph Gargiuli, Michael Adams, Ronald John Roberts, Bindhu Gururajan, David J. Parker, Gavin P. Reynolds, Thomas Leadbeater, Chuan-Yu Wu
© 2015. Milling is a critical process for controlling the properties of the granules produced by roll compaction. In the current study, the positron emission particle tracking (PEPT) technique was used to examine the milling kinematics of roll-compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb381a88713e3e1d9aa5d78a3c41b1db
https://surrey.eprints-hosting.org/808589/
https://surrey.eprints-hosting.org/808589/
