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MicroRNA-206 suppresses TGF-β signalling to limit tumor growth and metastasis in lung adenocarcinoma
Autor:
Peter Truesdell, Kathleen Watt, Daniel Newsted, Adrianna Majewski, Elena Voorand, Neil Renwick, Andrew W.B. Craig, Thomas Tuschl, Robert J. Gooding, Binchen Yao
Publikováno v:
Cellular signalling. 50
MicroRNA-206 (miR-206) has demonstrated tumor suppressive effects in a variety of cancers. Numerous studies have identified aberrantly expressed targets of miR-206 that contribute to tumor progression and metastasis, however, the broader gene-network