Cell-based strategies for IVD repair: clinical progress and translational obstacles.

Autor: Binch ALA; Regenerative Medicine Institute (REMEDI), National University of Ireland Galway, Galway, Ireland., Fitzgerald JC; Regenerative Medicine Institute (REMEDI), National University of Ireland Galway, Galway, Ireland., Growney EA; Regenerative Medicine Institute (REMEDI), National University of Ireland Galway, Galway, Ireland., Barry F; Regenerative Medicine Institute (REMEDI), National University of Ireland Galway, Galway, Ireland. frank.barry@nuigalway.ie.

Publikováno v: Nature reviews. Rheumatology [Nat Rev Rheumatol] 2021 Mar; Vol. 17 (3), pp. 158-175. Date of Electronic Publication: 2021 Feb 01.

Exploiting the role of nanoparticle shape in enhancing hydrogel adhesive and mechanical properties.

Autor: Arno MC; School of Chemistry, University of Birmingham, B15 2TT, Edgbaston, Birmingham, UK. m.c.arno@bham.ac.uk., Inam M; Department of Chemistry, University of Warwick, Gibbet Hill Road, CV4 7AL, Coventry, UK., Weems AC; School of Chemistry, University of Birmingham, B15 2TT, Edgbaston, Birmingham, UK., Li Z; School of Chemistry, University of Birmingham, B15 2TT, Edgbaston, Birmingham, UK.; Department of Chemistry, University of Warwick, Gibbet Hill Road, CV4 7AL, Coventry, UK., Binch ALA; Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, Manchester, M13 9PT, UK., Platt CI; Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, Manchester, M13 9PT, UK., Richardson SM; Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, Manchester, M13 9PT, UK., Hoyland JA; Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, Manchester, M13 9PT, UK.; NIHR Manchester Biomedical Research Centre, Central Manchester Foundation Trust, Manchester Academic Health Science Centre, 29 Grafton Street, Manchester, M13 9WL, UK., Dove AP; School of Chemistry, University of Birmingham, B15 2TT, Edgbaston, Birmingham, UK. a.dove@bham.ac.uk., O'Reilly RK; School of Chemistry, University of Birmingham, B15 2TT, Edgbaston, Birmingham, UK. r.oreilly@bham.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2020 Mar 17; Vol. 11 (1), pp. 1420. Date of Electronic Publication: 2020 Mar 17.

Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis.

Autor: Steinberg J; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.; Cancer Research Division, Cancer Council NSW, Sydney, NSW, 2011, Australia., Ritchie GRS; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.; Usher Institute of Population Health Sciences & Informatics, University of Edinburgh, Edinburgh, EH16 4UX, UK.; MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Roumeliotis TI; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Jayasuriya RL; Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK., Clark MJ; Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK., Brooks RA; Division of Trauma & Orthopaedic Surgery, University of Cambridge, Box 180, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, UK., Binch ALA; Biomolecular Sciences Research Centre, Sheffield Hallam University, Sheffield, S1 1WB, UK., Shah KM; Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK., Coyle R; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Pardo M; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Le Maitre CL; Biomolecular Sciences Research Centre, Sheffield Hallam University, Sheffield, S1 1WB, UK., Ramos YFM; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, 2300RC, The Netherlands., Nelissen RGHH; Department of Orthopedics, Leiden University Medical Center, Leiden, 2300RC, The Netherlands., Meulenbelt I; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, 2300RC, The Netherlands., McCaskie AW; Division of Trauma & Orthopaedic Surgery, University of Cambridge, Box 180, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, UK., Choudhary JS; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Wilkinson JM; Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK. j.m.wilkinson@sheffield.ac.uk., Zeggini E; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK. Eleftheria@sanger.ac.uk.

Publikováno v: Scientific reports [Sci Rep] 2017 Aug 21; Vol. 7 (1), pp. 8935. Date of Electronic Publication: 2017 Aug 21.

Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration.

Autor: Wang H; Department of Orthopaedic Surgery and Graduate Program in Cell and Developmental Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107; Department of Orthopaedics, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China., Tian Y; Department of Orthopaedic Surgery and Graduate Program in Cell and Developmental Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107; Department of Orthopaedic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China., Wang J; Department of Orthopaedic Surgery and Graduate Program in Cell and Developmental Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107., Phillips KLE; Biomedical Research Centre, Sheffield Hallam University, Sheffield S1 1WB, United Kingdom., Binch ALA; Biomedical Research Centre, Sheffield Hallam University, Sheffield S1 1WB, United Kingdom., Dunn S; Biomedical Research Centre, Sheffield Hallam University, Sheffield S1 1WB, United Kingdom., Cross A; Biomedical Research Centre, Sheffield Hallam University, Sheffield S1 1WB, United Kingdom., Chiverton N; Sheffield Teaching Hospitals National Health Services Foundation Trust, Sheffield S5 7AU, United Kingdom., Zheng Z; Department of Orthopaedics, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China., Shapiro IM; Department of Orthopaedic Surgery and Graduate Program in Cell and Developmental Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107., Le Maitre CL; Biomedical Research Centre, Sheffield Hallam University, Sheffield S1 1WB, United Kingdom., Risbud MV; Department of Orthopaedic Surgery and Graduate Program in Cell and Developmental Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107. Electronic address: makarand.risbud@jefferson.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2013 Jun 07; Vol. 288 (23), pp. 16761-16774. Date of Electronic Publication: 2013 Apr 15.