Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Binal N, Shah"'
Autor:
Xu Zhang, Jihyun Song, Binal N. Shah, Jin Han, Taif Hassan, Galina Miasniakova, Adelina Sergueeva, Sergei Nekhai, Roberto F. Machado, Mark T. Gladwin, Santosh L. Saraf, Josef T. Prchal, Victor R. Gordeuk
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Transcriptional changes in compensatory erythropoiesis in sickle cell anemia (SCA) and their disease modulation are unclear. We detected 1226 differentially expressed genes in hemoglobin SS reticulocytes compared to non-anemic hemoglobin AA
Externí odkaz:
https://doaj.org/article/28e138e102b34c009297029c6f5d995c
Autor:
Xu Zhang, Jihyun Song, Binal N. Shah, Jin Han, Taif Hassan, Galina Miasniakova, Adelina Sergueeva, Sergei Nekhai, Roberto F. Machado, Mark T. Gladwin, Santosh L. Saraf, Josef T. Prchal, Victor R. Gordeuk
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/573a5bc3df20468ea570fbd6777c5c58
Autor:
Mikhail S. Chesnokov, Marianna Halasi, Soheila Borhani, Zarema Arbieva, Binal N. Shah, Rick Oerlemans, Irum Khan, Carlos J. Camacho, Andrei L. Gartel
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-13 (2021)
Abstract FOXM1 transcription factor is an oncogene and a master regulator of chemoresistance in multiple cancers. Pharmacological inhibition of FOXM1 is a promising approach but has proven to be challenging. We performed a network-centric transcripto
Externí odkaz:
https://doaj.org/article/3babdd7ba88c4a3193ab9166ae0d1cb3
Autor:
Jin Han, Andrew Srisuwananukorn, Binal N. Shah, Robert E. Molokie, James P. Lash, Victor R. Gordeuk, Santosh L. Saraf
Publikováno v:
eJHaem, Vol 2, Iss 3, Pp 483-484 (2021)
Externí odkaz:
https://doaj.org/article/7517cc9f7f2d421cb056508ff7b57bad
Autor:
Maria A. Ruiz, Binal N. Shah, Guohui Ren, Faiz Hussain, Franklin Njoku, Roberto F. Machado, Victor R. Gordeuk, Santosh L. Saraf
Publikováno v:
Blood Advances. 6:6242-6248
Haptoglobin (HP) is an acute-phase protein and the main scavenger of cell-free hemoglobin. When HP is depleted, as observed in hemolytic conditions such as sickle cell disease (SCD), cell-free hemoglobin can lead to acute organ damage. The impact of
Autor:
Andria Mousa, Abdullah Al-Taiar, Nicholas M Anstey, Cyril Badaut, Bridget E Barber, Quique Bassat, Joseph D Challenger, Aubrey J Cunnington, Dibyadyuti Datta, Chris Drakeley, Azra C Ghani, Victor R Gordeuk, Matthew J Grigg, Pierre Hugo, Chandy C John, Alfredo Mayor, Florence Migot-Nabias, Robert O Opoka, Geoffrey Pasvol, Claire Rees, Hugh Reyburn, Eleanor M Riley, Binal N Shah, Antonio Sitoe, Colin J Sutherland, Philip E Thuma, Stefan A Unger, Firmine Viwami, Michael Walther, Christopher J M Whitty, Timothy William, Lucy C Okell
Publikováno v:
PLoS Medicine, Vol 17, Iss 10, p e1003359 (2020)
BackgroundDelay in receiving treatment for uncomplicated malaria (UM) is often reported to increase the risk of developing severe malaria (SM), but access to treatment remains low in most high-burden areas. Understanding the contribution of treatment
Externí odkaz:
https://doaj.org/article/ba8efe1bc73045abb15eedf4a63503a8
Autor:
Santosh L. Saraf, Titilola S. Akingbola, Binal N. Shah, Chinedu A. Ezekekwu, Omowunmi Sonubi, Xu Zhang, Lewis L. Hsu, Mark T. Gladwin, Roberto F. Machado, Richard S. Cooper, Victor R. Gordeuk, Bamidele O. Tayo
Publikováno v:
Blood Advances, Vol 1, Iss 11, Pp 693-698 (2017)
Abstract: α-Thalassemia and the BCL11A rs1427407 T allele are commonly observed in sickle cell anemia (SCA) patients and are associated with reduced hemolysis and higher hemoglobin F levels, respectively. We investigated whether a high-risk genetic
Externí odkaz:
https://doaj.org/article/e9e2897c2597416d93ab508448e3005a
Autor:
Irum Khan, Soheila Borhani, Marianna Halasi, Carlos J. Camacho, Zarema Arbieva, Binal N. Shah, Andrei L. Gartel, Mikhail S. Chesnokov, Rick Oerlemans
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
FOXM1 transcription factor is an oncogene and a master regulator of chemoresistance in multiple cancers. Pharmacological inhibition of FOXM1 is a promising approach but has proven to be challenging. We performed a network-centric transcriptomic analy
Autor:
Adelina Sergueeva, Galina Miasnikova, Binal N. Shah, Jihyun Song, Ekaterina Lisina, Daniel J. Okhotin, Mehdi Nouraie, Sergei Nekhai, Tatiana Ammosova, Xiao Mei Niu, Josef T. Prchal, Xu Zhang, Victor R. Gordeuk
Publikováno v:
Haematologica, Vol 102, Iss 5 (2017)
Externí odkaz:
https://doaj.org/article/4d4360be4c25495e987a089f701da167
Autor:
Santosh L. Saraf, Binal N. Shah, Xu Zhang, Jin Han, Bamidele O. Tayo, Taimur Abbasi, Adam Ostrower, Elizabeth Guzman, Robert E. Molokie, Michel Gowhari, Johara Hassan, Shivi Jain, Richard S. Cooper, Roberto F. Machado, James P. Lash, Victor R. Gordeuk
Publikováno v:
Haematologica, Vol 102, Iss 1 (2017)
Externí odkaz:
https://doaj.org/article/509ace851c6149ff8556644080d8ba20