Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Bin-Lin Song"'
Autor:
Yu-Jia Zhai, Bing-Chen Liu, Shi-Peng Wei, Chu-Fang Chou, Ming-Ming Wu, Bin-Lin Song, Valerie A. Linck, Li Zou, Shuai Zhang, Xue-Qi Li, Zhi-Ren Zhang, He-Ping Ma
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 3, Pp 1051-1059 (2018)
Background/Aims: The epithelial sodium channel (ENaC) in cortical collecting duct (CCD) principal cells plays a critical role in regulating systemic blood pressure. We have previously shown that cholesterol (Cho) in the apical cell membrane regulates
Externí odkaz:
https://doaj.org/article/dfaf7a60b0324aaab53855043374ac19
Autor:
Xiao-Qing Ding, Tao Ban, Zeng-Yan Liu, Jie Lou, Liang-Liang Tang, Jia-Xin Wang, Wen-Feng Chu, Dan Zhao, Bin-Lin Song, Zhi-Ren Zhang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 41, Iss 2, Pp 835-848 (2017)
Background/Aims: The present study investigated whether the transient receptor potential melastatin 4 (TRPM4) channel plays a role in high salt diet (HSD)-induced endothelial injuries. Methods: Western blotting and immunofluorescence were used to exa
Externí odkaz:
https://doaj.org/article/4023d5ab78ed4a7bb7be5dd4c1ec10ad
Autor:
Chang‐Jiang Yu, Liang‐Liang Tang, Chen Liang, Xiao Chen, Shu‐Ying Song, Xiao‐Qing Ding, Kun‐Yu Zhang, Bin‐Lin Song, Dan Zhao, Xue‐Yong Zhu, Hong‐Liang Li, Zhi‐Ren Zhang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 2 (2016)
BackgroundAngiotensin‐converting enzyme 3 (ACE3) is a recently defined homolog of ACE. However, the pathophysiological function of ACE3 is largely unknown. Here, we aim to explore the role of ACE3 in pathological cardiac hypertrophy. Methods and Re
Externí odkaz:
https://doaj.org/article/c4c39db23a9d4c7a884f4290fad394c5
Autor:
Yu-Jia Zhai, Qiang Yue, Valerie Linck, Shipeng Wei, Clintoria R. Williams, Bin-Lin Song, Chang Song, Li Zou, Shuai Zhang, Zhi-Ren Zhang, Ming-Ming Wu, He-Ping Ma
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1865:1915-1924
We have previously shown that blockade of ATP-binding cassette transporter A1 (ABCA1) with cyclosporine A (CsA) stimulates the epithelial sodium channel (ENaC) in cultured distal nephron cells. Here we show that CsA elevated systolic blood pressure i
Autor:
Wei-Wan Zheng, Qiu-Shi Wang, Ming-Ming Wu, Chen Liang, Xu Yang, Zhi-Ren Zhang, Jie Lou, Bin-Lin Song, Liang-Liang Tang, Na Niu, He-Ping Ma
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Previous studies have shown that high salt induces artery stiffness by causing endothelial dysfunction via increased sodium influx. We used our unique split-open artery technique combined with protein biochemistry and in vitro measurement of vascular
Autor:
Bin-Lin Song, Li Zou, Yu-Jia Zhai, Bing-Chen Liu, Valerie Linck, Chu-Fang Chou, Xueqi Li, He-Ping Ma, Shipeng Wei, Ming-Ming Wu, Shuai Zhang, Zhi-Ren Zhang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 3, Pp 1051-1059 (2018)
Background/Aims: The epithelial sodium channel (ENaC) in cortical collecting duct (CCD) principal cells plays a critical role in regulating systemic blood pressure. We have previously shown that cholesterol (Cho) in the apical cell membrane regulates
Autor:
Na Niu, Qing-Qing Hu, Ming-Ming Wu, Qiu-Shi Wang, Zhi-Ren Zhang, Bao-Long Zhang, Xu Yang, Bin-Lin Song, Chen Liang, Chang-Jiang Yu, He-Ping Ma, Xiao Chen
Publikováno v:
British Journal of Pharmacology. 175:1318-1328
Background and purpose The epithelial sodium channel (ENaC) is expressed in endothelial cells and acts as a negative modulator of vasodilatation. Oxidized LDL (ox-LDL) is a key pathological factor in endothelial dysfunction. In the present study we e
Autor:
He-Ping Ma, Qing-Qing Hu, Jian-Jun Mu, Zi-Rui Wang, Wei-Wan Zheng, Zu-Yi Yuan, Hui-Bin Liu, Ying-Ying Sun, Zhi-Ren Zhang, Xin-Yuan Li, Bin-Lin Song, Ming-Ming Wu, Chang-Jiang Yu, Yu-Xia Li
Publikováno v:
British Journal of Pharmacology. 175:1305-1317
Background and purpose Our recent studies show that the reduced activity of epithelial sodium channels (ENaC) in endothelial cells accounts for the adaptation of vasculature to salt in Sprague-Dawley rats. The present study examines a hypothesis that
Autor:
Xiao-Di Yu, Na Niu, Shuai Zhang, Zhi-Ren Zhang, Tiffany L. Thai, He-Ping Ma, Ming-Ming Wu, Roy L. Sutliff, Bin-Lin Song, Jing Ma, Xu Yang, Valerie Linck, Li Zou, Yu-Jia Zhai, Bao-Long Zhang, Yong-Xu Cai, Qiang Yue, Qiu-Shi Wang, Chen Liang
Publikováno v:
Br J Pharmacol
Background and purpose We have shown that cholesterol is synthesized in the principal cells of renal cortical collecting ducts (CCD) and stimulates the epithelial sodium channels (ENaC). Here we have determined whether lovastatin, a cholesterol synth
Autor:
Xu Yang, Qiu-Shi Wang, Xiao Chen, Chen Liang, Ming-Ming Wu, Na Niu, Bin-Lin Song, Chang-Jiang Yu, He-Ping Ma, Zhi-Ren Zhang
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2018 (2018)
Oxidative Medicine and Cellular Longevity, Vol 2018 (2018)
Previous studies indicate that the epithelial sodium channel (ENaC) in the kidney is upregulated in diabetes mellitus. Here, we show that ENaC single-channel activity in distal nephron cells was significantly increased by palmitate, a free fatty acid