Zobrazeno 1 - 10
of 827
pro vyhledávání: '"Bin Tean Teh"'
Autor:
Peiyong Guan, Jianfeng Chen, Chengqiang Mo, Tomoya Fukawa, Chao Zhang, Xiuyu Cai, Mei Li, Jing Han Hong, Jason Yongsheng Chan, Cedric Chuan Young Ng, Jing Yi Lee, Suet Far Wong, Wei Liu, Xian Zeng, Peili Wang, Rong Xiao, Vikneswari Rajasegaran, Swe Swe Myint, Abner Ming Sun Lim, Joe Poh Sheng Yeong, Puay Hoon Tan, Choon Kiat Ong, Tao Xu, Yiqing Du, Fan Bai, Xin Yao, Bin Tean Teh, Jing Tan
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2132-2145 (2024)
Abstract Collecting duct carcinoma (CDC) is an aggressive rare subtype of kidney cancer with unmet clinical needs. Little is known about its underlying molecular alterations and etiology, primarily due to its rarity, and lack of preclinical models. T
Externí odkaz:
https://doaj.org/article/26e77e47357b4536980d9f63bd24fbcb
Autor:
Patrick S. Plum, Timo Hess, Denis Bertrand, Isabelle Morgenstern, Oscar Velazquez Camacho, Christoph Jonas, Christina Alidousty, Britta Wagner, Stephanie Roessler, Thomas Albrecht, Jessica Becker, Vanessa Richartz, Barbara Holz, Sascha Hoppe, Huay Mei Poh, Burton Kuan Hui Chia, Cheryl Xueli Chan, Thushangi Pathiraja, Audrey SM Teo, Jens U. Marquardt, Alexis Khng, Michael Heise, Yao Fei, René Thieme, Sebastian Klein, Jing Han Hong, Simona O Dima, Irinel Popescu, Maria Hoppe‐Lotichius, Reinhard Buettner, Anja Lautem, Gerd Otto, Alexander Quaas, Niranjan Nagarajan, Steve Rozen, Bin Tean Teh, Benjamin Goeppert, Uta Drebber, Hauke Lang, Patrick Tan, Ines Gockel, Johannes Schumacher, Axel M. Hillmer
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 6, Pp n/a-n/a (2024)
Abstract Background Cholangiocarcinoma (CCA) is a fatal cancer of the bile duct with a poor prognosis owing to limited therapeutic options. The incidence of intrahepatic CCA (iCCA) is increasing worldwide, and its molecular basis is emerging. Environ
Externí odkaz:
https://doaj.org/article/26260a111e4f40929c73d9cf914a4148
Autor:
Qiu Xuan Tan, Nicholas B. Shannon, Weng Khong Lim, Jing Xian Teo, Daniel R. Y. Yap, Sze Min Lek, Joey W. S. Tan, Shih Jia J. Tan, Josephine Hendrikson, Ying Liu, Gillian Ng, Clara Y. L. Chong, Wanyu Guo, Kelvin K. N. Koh, Cedric C. Y. Ng, Vikneswari Rajasegaran, Jolene S.M. Wong, Chin Jin Seo, Choon Kiat Ong, Tony K. H. Lim, Bin Tean Teh, Oi Lian Kon, Claramae S. Chia, Khee Chee Soo, N. Gopalakrishna Iyer, Chin-Ann J. Ong
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionField cancerization is suggested to arise from imbalanced differentiation in individual basal progenitor cells leading to clonal expansion of mutant cells that eventually replace the epithelium, although without evidence.MethodsWe perform
Externí odkaz:
https://doaj.org/article/281912497fc44f628bdcedeb2a207a97
Autor:
Jui Wan Loh, Jing Yi Lee, Abner Herbert Lim, Peiyong Guan, Boon Yee Lim, Bavani Kannan, Elizabeth Chun Yong Lee, Ning Xin Gu, Tun Kiat Ko, Cedric Chuan-Young Ng, Jeffrey Chun Tatt Lim, Joe Yeong, Jing Quan Lim, Choon Kiat Ong, Bin Tean Teh, Jason Yongsheng Chan
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-9 (2023)
Abstract Angiosarcomas are rare malignant tumors of the endothelium, arising commonly from the head and neck region (AS-HN) and recently associated with ultraviolet (UV) exposure and human herpesvirus-7 infection. We examined 81 cases of angiosarcoma
Externí odkaz:
https://doaj.org/article/3d3a36688b6b49a987aef402e70d7aba
Autor:
Jinghong Chen, Zhixiang Zuo, Yan Gao, Xiaosai Yao, Peiyong Guan, Yali Wang, Zhimei Li, Zhilong Liu, Jing Han Hong, Peng Deng, Jason Yongsheng Chan, Daryl Ming Zhe Cheah, Jingquan Lim, Kelila Xin Ye Chai, Burton Kuan Hui Chia, Jane Wan Lu Pang, Joanna Koh, Dachuan Huang, Haixia He, Yichen Sun, Lizhen Liu, Shini Liu, Yuhua Huang, Xiaoxiao Wang, Hua You, Sahil Ajit Saraf, Nicholas Francis Grigoropoulos, Xiaoqiu Li, Jinxin Bei, Tiebang Kang, Soon Thye Lim, Bin Tean Teh, Huiqiang Huang, Choon Kiat Ong, Jing Tan
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background Natural killer/T-cell lymphoma (NKTL) is a rare type of aggressive and heterogeneous non-Hodgkin's lymphoma (NHL) with a poor prognosis and limited therapeutic options. Therefore, there is an urgent need to exploit potential novel
Externí odkaz:
https://doaj.org/article/63014556270748ed98fa1bb18898c8a1
Autor:
Divya Khosla, Shagun Misra, Pek Lim Chu, Peiyong Guan, Ritambhra Nada, Rajesh Gupta, Khwanta Kaewnarin, Tun Kiat Ko, Hong Lee Heng, Vijay Kumar Srinivasalu, Rakesh Kapoor, Deepika Singh, Poramate Klanrit, Somponnat Sampattavanich, Jing Tan, Sarinya Kongpetch, Apinya Jusakul, Bin Tean Teh, Jason Yongsheng Chan, Jing Han Hong
Publikováno v:
Cancers, Vol 16, Iss 4, p 801 (2024)
Cholangiocarcinomas (CCA) pose a complex challenge in oncology due to diverse etiologies, necessitating tailored therapeutic approaches. This review discusses the risk factors, molecular pathology, and current therapeutic options for CCA and explores
Externí odkaz:
https://doaj.org/article/fba92e29db7c4b5fb94759ca636ebf0d
Autor:
Yali Wang, Wenbo Zhou, Jianfeng Chen, Jinghong Chen, Peng Deng, Huang Chen, Yichen Sun, Zhaoliang Yu, Diwen Pang, Lizhen Liu, Peili Wang, Jing Han Hong, Bin Tean Teh, Huiqiang Huang, Wenyu Li, Zhengfang Yi, Soon Thye Lim, Yihua Chen, Choon Kiat Ong, Mingyao Liu, Jing Tan
Publikováno v:
MedComm, Vol 4, Iss 4, Pp n/a-n/a (2023)
Abstract Natural killer/T‐cell lymphoma (NKTL) is an uncommon malignancy with poor prognosis and limited therapeutic options. Activating mutations of signal transducer and activator of transcription 3 (STAT3) are frequently found in patients with N
Externí odkaz:
https://doaj.org/article/e18efbf266124b799349530a6ced4565
Autor:
Cheng-Yong Tham, LaiFong Poon, TingDong Yan, Javier Yu Peng Koh, Muhammad Khairul Ramlee, Vania Swee Imm Teoh, Suihan Zhang, Yi Cai, Zebin Hong, Gina S. Lee, Jin Liu, Hai Wei Song, William Ying Khee Hwang, Bin Tean Teh, Patrick Tan, Lifeng Xu, Angela S. Koh, Motomi Osato, Shang Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
There exist challenges in quantifying the length of individual telomeres at single nucleotide resolution. Here the authors report a method to capture telomeres and accurately analyse their length in human cell lines and patient peripheral blood leuko
Externí odkaz:
https://doaj.org/article/64cb1ffc77e441ea9cb04a62de2be0e9
Autor:
Jian Yuan Goh, Chik Hong Kuick, Masahiro Sugiura, Sze Jet Aw, Manli Zhao, Hongfeng Tang, Sandini Gunaratne, Fucun Zhu, Lin Cai, Bin Tean Teh, Paul S Thorner, Kenneth Tou En Chang
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 5, Pp 470-480 (2022)
Abstract Clear cell sarcoma of the kidney (CCSK) and primitive myxoid mesenchymal tumour of infancy (PMMTI) are paediatric sarcomas that most commonly harbour internal tandem duplications (ITDs) of exon 15 of the BCOR gene, in the range of 87–114 b
Externí odkaz:
https://doaj.org/article/4dac882e8cc042cfab36d2273f2584be
Autor:
Abner Herbert Lim, Zhen Jie Low, Prashant Narendra Shingate, Jing Han Hong, Shu Chen Chong, Cedric Chuan Young Ng, Wei Liu, Robert Vaser, Mile Šikić, Wing-Kin Ken Sung, Niranjan Nagarajan, Patrick Tan, Bin Tean Teh
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Genome assembly and metabolomic analysis of Singapore’s national flower, Papilionanthe (Ple.) Miss Joaquim “Agnes” (PMJ), expands the known genetic repertoire of the Orchidaceae family and insights into the biochemical processes of PMJ.
Externí odkaz:
https://doaj.org/article/57deaff736324f6cbaf969e69093bdfb