Zobrazeno 1 - 10
of 824
pro vyhledávání: '"Bin‐Tean Teh"'
Autor:
Shini Liu, Peng Deng, Zhaoliang Yu, Jing Han Hong, Jiuping Gao, Yulin Huang, Rong Xiao, Jiaxin Yin, Xian Zeng, Yichen Sun, Peili Wang, Ruizi Geng, Jason Yongsheng Chan, Peiyong Guan, Qiang Yu, Bin‐Tean Teh, Qingping Jiang, Xiaojun Xia, Ying Xiong, Jianfeng Chen, Yongliang Huo, Jing Tan
Publikováno v:
Advanced Science, Vol 11, Iss 45, Pp n/a-n/a (2024)
Abstract Poly (ADP‐ribose) Polymerase inhibitors (PARPi) have demonstrated remarkable clinical efficacy in treating ovarian cancer (OV) with BRCA1/2 mutations. However, drug resistance inevitably limits their clinical applications and there is an u
Externí odkaz:
https://doaj.org/article/a6bbf8a7716f41d0811c53e342b2b0f7
Autor:
Jingting Wu, Hannah Chi, Shawn Kok, Jason M.W. Chua, Xi-Xiao Huang, Shipin Zhang, Shimin Mah, Li-Xin Foo, Hui-Yee Peh, Hui-Bing Lee, Phoebe Tay, Cherie Tong, Jasmine Ladlad, Cheryl H.M. Tan, Nathanelle Khoo, Darius Aw, Cheryl X.Z. Chong, Leonard M.L. Ho, Sharmini S. Sivarajah, Jialin Ng, Winson J.H. Tan, Fung-Joon Foo, Bin-Tean Teh, Frederick H. Koh
Publikováno v:
Annals of Coloproctology, Vol 40, Iss 1, Pp 3-12 (2024)
Sarcopenia, which is characterized by progressive and generalized loss of skeletal muscle mass and strength, has been well described to be associated with numerous poor postoperative outcomes, such as increased perioperative mortality, postoperative
Externí odkaz:
https://doaj.org/article/05aab6ab6a954c4eb8ea880edcece22a
Autor:
Jianfeng Chen, Jing Han Hong, Yulin Huang, Shini Liu, Jiaxin Yin, Peng Deng, Yichen Sun, Zhaoliang Yu, Xian Zeng, Rong Xiao, Jason Yongsheng Chan, Peiyong Guan, Yali Wang, Peili Wang, Lizhen Liu, Shijun Wen, Qiang Yu, Choon Kiat Ong, Bin-Tean Teh, Ying Xiong, Jing Tan
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-15 (2023)
Abstract Background Enhancer of zeste homolog 2 (EZH2), the key catalytic subunit of polycomb repressive complex 2 (PRC2), is overexpressed and plays an oncogenic role in various cancers through catalysis-dependent or catalysis-independent pathways.
Externí odkaz:
https://doaj.org/article/b67020e61b6748208cb6b5f34e466c59
Autor:
Jian Yuan Goh, Chik Hong Kuick, Masahiro Sugiura, Sze Jet Aw, Manli Zhao, Hongfeng Tang, Sandini Gunaratne, Fucun Zhu, Lin Cai, Bin Tean Teh, Paul S Thorner, Kenneth Tou En Chang
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 5, Pp 470-480 (2022)
Abstract Clear cell sarcoma of the kidney (CCSK) and primitive myxoid mesenchymal tumour of infancy (PMMTI) are paediatric sarcomas that most commonly harbour internal tandem duplications (ITDs) of exon 15 of the BCOR gene, in the range of 87–114 b
Externí odkaz:
https://doaj.org/article/4dac882e8cc042cfab36d2273f2584be
Autor:
Abner Herbert Lim, Zhen Jie Low, Prashant Narendra Shingate, Jing Han Hong, Shu Chen Chong, Cedric Chuan Young Ng, Wei Liu, Robert Vaser, Mile Šikić, Wing-Kin Ken Sung, Niranjan Nagarajan, Patrick Tan, Bin Tean Teh
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Genome assembly and metabolomic analysis of Singapore’s national flower, Papilionanthe (Ple.) Miss Joaquim “Agnes” (PMJ), expands the known genetic repertoire of the Orchidaceae family and insights into the biochemical processes of PMJ.
Externí odkaz:
https://doaj.org/article/57deaff736324f6cbaf969e69093bdfb
Autor:
Dave Yong Xiang Ng, Zhimei Li, Elizabeth Lee, Jessica Sook Ting Kok, Jing Yi Lee, Joanna Koh, Cedric Chuan-Young Ng, Abner Herbert Lim, Wei Liu, Sheng Rong Ng, Kah Suan Lim, Xi Xiao Huang, Jing Han Hong, Peiyong Guan, Yirong Sim, Aye Aye Thike, Nur Diyana Md Nasir, Shang Li, Puay Hoon Tan, Bin Tean Teh, Jason Yongsheng Chan
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Malignant phyllodes tumors (PT) are rare aggressive fibroepithelial neoplasms with high metastatic potential and lack effective therapy. We established a patient-derived xenograft (PDX) and cell line model (designated MPT-S1) of malignant PT
Externí odkaz:
https://doaj.org/article/bd28bd0bf05246bbaccb1e4e99e36462
Autor:
Cedric Chuan-Young Ng, Sandy Lim, Abner Herbert Lim, Nur Diyana Md Nasir, Jingxian Zhang, Vikneswari Rajasegaran, Jing Yi Lee, Jessica Sook Ting Kok, Aye Aye Thike, Johnathan Xiande Lim, Ruifen Weng, Sidney Yee, Yukti Choudhury, Jason Yongsheng Chan, Puay Hoon Tan, Min-Han Tan, Bin Tean Teh
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Introduction: A well-validated diagnostic assay with curated biomarkers complements clinicopathological factors to facilitate early diagnosis and ensure timely treatment delivery. This study focuses on an Asian-centric cancer diagnostic assay designe
Externí odkaz:
https://doaj.org/article/01db8eb942f6482085e4d3ecfd293907
Autor:
Jason Yongsheng Chan, Grace Fangmin Tan, Joe Yeong, Chee Wee Ong, Dave Yong Xiang Ng, Elizabeth Lee, Joanna Koh, Cedric Chuan-Young Ng, Jing Yi Lee, Wei Liu, Ru Xin Wong, Chin-Ann Johnny Ong, Mohamad Farid, Bin Tean Teh, Khee Chee Soo
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-13 (2021)
Abstract Angiosarcomas are a rare subtype of soft-tissue sarcomas which exhibit aggressive clinical phenotypes with limited treatment options and poor outcomes. In this study, we investigated the clinical relevance of the peripheral blood neutrophil-
Externí odkaz:
https://doaj.org/article/5d397cd279614abe8c61f05978d8c078
Autor:
Yasmin Bylstra, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R. Ryanne Wu, Jing Xian Teo, Sonia Davila, Jyn Ling Kuan, Sock Hoai Chan, Nicolas Bertin, Cheng Xi Yang, Steve Rozen, Bin Tean Teh, Khung Keong Yeo, Stuart Alexander Cook, Saumya Shekhar Jamuar, Geoffrey S. Ginsburg, Lori A. Orlando, Patrick Tan
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-11 (2021)
Abstract Background Family history has traditionally been an essential part of clinical care to assess health risks. However, declining sequencing costs have precipitated a shift towards genomics-first approaches in population screening programs rend
Externí odkaz:
https://doaj.org/article/c63732b2d27a4a86a9c0d7a20529368c
Autor:
Sarinya Kongpetch, Apinya Jusakul, Jing Quan Lim, Cedric Chuan Young Ng, Jason Yongsheng Chan, Vikneswari Rajasegaran, Tse Hui Lim, Kiat Hon Lim, Su Pin Choo, Simona Dima, Irinel Popescu, Dan G. Duda, Veerapol Kukongviriyapan, Narong Khuntikeo, Chawalit Pairojkul, Steven G. Rozen, Patrick Tan, Bin Tean Teh
Publikováno v:
JCO Global Oncology, Vol , Iss 6, Pp 628-638 (2020)
PURPOSE Cholangiocarcinoma (CCA) remains a disease with poor prognosis and limited therapeutic options. Identification of driver genetic alterations may lead to the discovery of more effective targeted therapies. CCAs harboring FGFR2 fusions have rec
Externí odkaz:
https://doaj.org/article/10fa1389d83040b8a3bd96d6fb1d277e