Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Bimalendu Dasmahapatra"'
Autor:
Bimalendu Dasmahapatra, Doll Ronald J, Cheng Li, Alan K. Mallams, David Hesk, Mark Demma, Robert A. Ramos, Eugene Maxwell, Ming Liu, Cynthia Seidel-Dugan, Lianzhu Liang, W. Robert Bishop, Randall R. Rossman
Publikováno v:
Journal of Biological Chemistry. 285:10198-10212
Abrogation of p53 function occurs in almost all human cancers, with more than 50% of cancers harboring inactivating mutations in p53 itself. Mutation of p53 is indicative of highly aggressive cancers and poor prognosis. The vast majority of mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2751a61b2624a2436872d6fd9bf2db9f
https://doi.org/10.1074/jbc.m109.083469
https://doi.org/10.1074/jbc.m109.083469
Publikováno v:
The Journal of biological chemistry. 279(44)
The p53 protein plays a major role in the maintenance of genome stability in mammalian cells. Mutations of p53 occur in over 50% of all cancers and are indicative of highly aggressive cancers that are hard to treat. Recently, there has been a high de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7664b29084aae04104ac307cacd7ca
https://pubmed.ncbi.nlm.nih.gov/15308639
https://pubmed.ncbi.nlm.nih.gov/15308639
Autor:
Nancy Butkiewicz, Winifred W. Prosise, Anthony Tsarbopoulos, Michael B. Cable, S. Shane Taremi, Bimalendu Dasmahapatra, Thomas Hesson, Hung Van Le, Patricia C. Weber
Publisher Summary Cytomegalovirus (CMV) protease is a serine protease, and labeling with diisopropylfluorophosphate (DFP) has identified Ser132 as the active site serine. The structure of the CMV protease containing the diisopropylphosphorylserine at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cce51b8c6fc5cb0b26f0764ab49ce08
https://doi.org/10.1016/s1080-8914(97)80027-0
https://doi.org/10.1016/s1080-8914(97)80027-0
Autor:
Frank Bennett, Ashit K. Ganguly, Nancy Butkiewicz, Naginbhai M. Patel, Viyyoor M. Girijavallabhan, Andrea Hart, Bimalendu Dasmahapatra
Publikováno v:
Bioorganicmedicinal chemistry. 2(10)
The syntheses, enzyme inhibition and antiviral activity of potent HIV-protease inhibitors containing novel β-hydroxy ether and thioethers based on the transition state mimetic concept are discussed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbde7121c63d738c7f2698a9191c09c
https://pubmed.ncbi.nlm.nih.gov/7773624
https://pubmed.ncbi.nlm.nih.gov/7773624
Autor:
Bimalendu Dasmahapatra
Publisher Summary This chapter discusses the use of insect virus translational initiation signal for in vitro gene expression. Gene expression in a cell-free system avoids various cellular regulatory mechanisms that often pose serious problems for in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3371d38babbc20eab8554cec1b681059
https://doi.org/10.1016/0076-6879(93)17060-i
https://doi.org/10.1016/0076-6879(93)17060-i
Autor:
Sheila Dwyer, Bimalendu Dasmahapatra, Jerome Schwartz, Jun Ma, Ivan Sadowski, Beth DiDomenico
We describe a genetic system for monitoring the activity of a specific proteolytic enzyme by taking advantage of the properties of the yeast transcriptional activator GAL4. The GAL4 protein contains two separable and functionally essential domains: t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b8ef4d9036b1000c5d9d1ebe14f67b
https://europepmc.org/articles/PMC525652/
https://europepmc.org/articles/PMC525652/
Publikováno v:
Virus research. 20(3)
We have expressed the 3C protease of coxsackievirus B3 (CVB3) in a cell-free system. This expression system employs the translational initiation signal of an insect virus RNA, black beetle virus (BBV) RNA 1, to direct CVB3-specific protein synthesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe8f1f9f894dbbe69f962b039dded03
https://pubmed.ncbi.nlm.nih.gov/1767582
https://pubmed.ncbi.nlm.nih.gov/1767582
Publikováno v:
Biochemical and biophysical research communications. 177(1)
Alpha complementation of beta-galactosidase (beta gal) is intracistronic and requires interaction between the alpha donor region (residues 3-41) and alpha acceptor fragment (produced by M15). We have constructed two plasmids which direct the synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2184158633ce687ffc219c59923b89
https://pubmed.ncbi.nlm.nih.gov/1904218
https://pubmed.ncbi.nlm.nih.gov/1904218
Publikováno v:
Journal of Molecular Biology
The black beetle virus (BBV) is an isometric insect virus whose genome consists of two messenger-active RNA molecules encapsidated in a single virion. The nucleotide sequence of BBV RNA1 (3105 bases) has been determined, and this, together with the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782cba0bce3f98ce08964eea699f1ead
https://doi.org/10.1016/0022-2836(85)90337-7
https://doi.org/10.1016/0022-2836(85)90337-7
Autor:
Bernard H. Selling, Keith Saunders, Bimalendu Dasmahapatra, Paul Kaesberg, Ranjit Dasgupta, Tom Gallagher
Publikováno v:
Proceedings of the National Academy of Sciences. 83:63-66
RNA transcripts of cloned cDNA of the genomic RNAs of BBV (black beetle virus) are infectious to cultured cells of Drosophila melanogaster. Individual transcripts had approximately 10% of the infectivity of the corresponding authentic virion RNA. Pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d5f6a347b234954a318befff2615d5
https://doi.org/10.1073/pnas.83.1.63
https://doi.org/10.1073/pnas.83.1.63