Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bilyana Doncheva"'
Autor:
Belén P. Solans, Paul Veys, Bilyana Doncheva, Helen Prunty, Robert Chiesa, Iñaki F. Trocóniz, Joseph F. Standing
Publikováno v:
Br J Clin Pharmacol
Aims Busulfan and treosulfan are cytotoxic agents used in the conditioning regime prior to paediatric haematopoietic stem cell transplantation (HSCT). These agents cause suppression of myeloid cells leaving patients severely immunocompromised in the
Autor:
Andrew R. Gennery, Persis Amrolia, David J. Kavanagh, Reem Elfeky, Stephen Owens, Joseph F. Standing, Robert Chiesa, Patrick R. Walsh, Austen Worth, Su-Han Lum, Helen K. Young, Kanchan Rao, Zohreh Nademi, Roderick Skinner, A Battersby, Claire Booth, Andrew J. Cant, Sinead Greener, Paul Veys, Mary Slatter, Giorgio Ottaviano, Natalia Builes, Bilyana Doncheva, Terence J. Flood, Waseem Qasim, Srinivas Annavarapu, Giovanna Lucchini
Publikováno v:
Blood Adv
This study aimed to identify a risk profile for development of transplant-associated thrombotic microangiopathy (TA-TMA) in children undergoing hematopoietic stem cell transplantation (HSCT). Between 2013 and 2016, 439 children underwent 474 HSCTs at
Autor:
Jan Chu, Paul Veys, Kanchan Rao, Danielle Pinner, Kirsty Devine, Zohreh Nademi, Oana Ciocarlie, Susan McLellen, Helen Prunty, Arina Lazareva, Frank Kloprogge, Sophie Hambleton, Persis Amrolia, Bilyana Doncheva, Robert Winter, Mary Slatter, Andrew R. Gennery, Robert Chiesa, Joseph F. Standing, Simon Heales, Giovanna Lucchini, Andrew J. Cant, Terence J. Flood, Juliana M.F. Silva, Elizabeth Rogerson
Publikováno v:
Clinical Pharmacology and Therapeutics
Treosulfan is given off-label in pediatric allogeneic hematopoietic stem cell transplant. This study investigated treosulfan's pharmacokinetics (PKs), efficacy, and safety in a prospective trial. Pediatric patients (n = 87) receiving treosulfan-fluda
Autor:
Joseph F. Standing, Adam Irwin, Frank Kloprogge, John Booth, Robert Chiesa, Bilyana Doncheva, Carlos Alonso, Charmion Lee, Iek Leng Cheng, Sophida Boonsathorn
Publikováno v:
Clinical Pharmacokinetics
The objectives of this study were to investigate the population pharmacokinetics of posaconazole in immunocompromised children, evaluate the influence of patient characteristics on posaconazole exposure and perform simulations to recommend optimal st