Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Bilyana C. Popova"'
Publikováno v:
Proceedings of the National Academy of Sciences. 103:7706-7711
X inactivation in female mammals involves transcriptional silencing of an entire chromosome in response to a cis-acting noncoding RNA, the X inactive-specific transcript ( Xist ). Xist can also inactivate autosomal sequences, for example, in X;autoso
Autor:
Thomas Jenuwein, Neil Brockdorff, Bilyana C. Popova, Jacqueline E. Mermoud, Antoine H.F.M. Peters
Publikováno v:
Current Biology. 12:247-251
In female mammals, a single X chromosome is stably and heritably silenced early in embryogenesis [1]. The inactive X is characterized by asynchronous DNA replication [2, 3] and epigenetic chromatin modifications, including DNA methylation [4], histon