Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Billy J. Roberts"'
Autor:
Billy J Roberts II
Mike Davis, who is the star of the story, starts to find his faith as he starts to get back to his Christian roots. He starts to remember what his parents taught him when he was young. He also struggles to figure out a way by which to come to terms w
Autor:
Billy J Roberts II
Mike Davis struggles to find himself after he was attacked in LA. The attack will set the stage for a major transformation in his life. While this transformation will significantly impact his life, it will set the stage for him to try to reform his r
Autor:
James M. Nelson, Danielle M. Amato, William A. Denny, Patricia J. Harvey, Veronica Sherwood, R. Thomas Winters, David W. Fry, Sylvester R. Klutchko, Jeff B. Smaill, Zhou Hairong, Paul A. Ellis, Hyo Kyung Han, Mary Ann Meade, Gerry Pace, H. D. Hollis Showalter, Tuan P. Tran, William L. Elliott, Billy J. Roberts, Irene W. Althaus, Alexander James Bridges, Andrea J. Gonzales
Publikováno v:
Journal of Medicinal Chemistry. 49:1475-1485
Structure-activity relationships for inhibition of erbB1, erbB2, and erbB4 were determined for a series of alkynamide analogues of quinazoline- and pyrido[3,4-d]pyrimidine-based compounds. The compounds were prepared by coupling the appropriate 6-ami
Autor:
William L. Elliott, Steven E. Rose, Patrick W. Vincent, Sandra J. Patmore, Veronika Sherwood, David W. Fry, Hairong Zhou, Wilber R. Leopold, Billy J. Roberts, Alex J. Bridges, Donald J. Dykes
Publikováno v:
Cancer Chemotherapy and Pharmacology. 45:231-238
Purpose: The involvement of the EGF receptor (EGFr) family of receptors in cancers suggests that a selective inhibitor of the tyrosine kinase activity of the EGFr family could have a therapeutic effect. PD 0169414, an anilinoquinazoline, is a potent
Publikováno v:
Investigational New Drugs. 9:1-8
The antitumor activity of [SP-4-3-(R)]-[1,1-cyclobutanedicarboxylato-(2-)](2 methyl-1,4-butanediamine-N,N')platinum (CI-973) was characterized in a number of preclinical model systems. CI-973 retained substantial activity in cisplatin resistant murin
Autor:
Patrick W. Vincent, Aneesa M. Amar, Gina H. Lu, Diane H. Boschelli, James M. Nelson, Hussein Hallak, Sylvester Klutchko, Donald J. Dykes, Laura A. Bradford, Panek Rl, Chad L. Stoner, Wayne D. Klohs, James M. Hamby, Brian G. Hartl, H. D. Hollis Showalter, Randall W. Steinkampf, Alan J. Kraker, Annette M. Doherty, Billy J. Roberts, Cynthia Shen, William L. Elliott, Terry C. Major, Tawny K. Dahring, Zhipei Wu, Denise L. Driscoll
Publikováno v:
Journal of medicinal chemistry. 41(17)
While engaged in therapeutic intervention against a number of proliferative diseases, we have discovered the 2-aminopyrido[2, 3-d]pyrimidin-7(8H)-ones as a novel class of potent, broadly active tyrosine kinase (TK) inhibitors. An efficient route was
Autor:
Jeff W. Kampf, Billy J. Roberts, H. D. Hollis Showalter, Alan J. Kraker, James D. Hoeschele, William L. Elliott
Publikováno v:
Journal of medicinal chemistry. 37(17)
The first two analogs 5a,b of a new class of neutral large-ring square-planar Pt(II) chelate complexes of the generic structure [Pt(cis-1,4-dach)X2] were synthesized via a refined technique, structurally characterized by NMR (1H, 13C, 195Pt), FAB mas
Autor:
Billy J. Roberts, David W. Fry, Kenneth E. Hook, Theodore J. Boritzki, Wilbur R. Leopold, Robert C. Jackson
Publikováno v:
Advances in Enzyme Regulation. 23:193-215
1. 1. CI-920 is a structurally novel, phosphate-containing polyene lactone antitumor agent isolated from a previously undescribed subspecies of Streptomyces pulveraceus cultured from a Brazilian soil sample. 2. 2. CI-920 was active against murine leu
Publikováno v:
Boston University Law Review. Mar2023, Vol. 103 Issue 2, p525-562. 38p.