Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Billy J Roberts"'
Autor:
Billy J Roberts II
Mike Davis, who is the star of the story, starts to find his faith as he starts to get back to his Christian roots. He starts to remember what his parents taught him when he was young. He also struggles to figure out a way by which to come to terms w
Autor:
Billy J Roberts II
Jordan, Florence, Zoe and Madelyn's friendship is put to the ultimate test when a terrible tragedy is revealed. How far will these women go to prove their loyalty? And will they take matters into their own hands? Each one of them is on a journey of t
Autor:
James M. Nelson, Danielle M. Amato, William A. Denny, Patricia J. Harvey, Veronica Sherwood, R. Thomas Winters, David W. Fry, Sylvester R. Klutchko, Jeff B. Smaill, Zhou Hairong, Paul A. Ellis, Hyo Kyung Han, Mary Ann Meade, Gerry Pace, H. D. Hollis Showalter, Tuan P. Tran, William L. Elliott, Billy J. Roberts, Irene W. Althaus, Alexander James Bridges, Andrea J. Gonzales
Publikováno v:
Journal of Medicinal Chemistry. 49:1475-1485
Structure-activity relationships for inhibition of erbB1, erbB2, and erbB4 were determined for a series of alkynamide analogues of quinazoline- and pyrido[3,4-d]pyrimidine-based compounds. The compounds were prepared by coupling the appropriate 6-ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21abfede32f22f167677e3f652089d6a
https://doi.org/10.1021/jm050936o
https://doi.org/10.1021/jm050936o
Autor:
William L. Elliott, Steven E. Rose, Patrick W. Vincent, Sandra J. Patmore, Veronika Sherwood, David W. Fry, Hairong Zhou, Wilber R. Leopold, Billy J. Roberts, Alex J. Bridges, Donald J. Dykes
Publikováno v:
Cancer Chemotherapy and Pharmacology. 45:231-238
Purpose: The involvement of the EGF receptor (EGFr) family of receptors in cancers suggests that a selective inhibitor of the tyrosine kinase activity of the EGFr family could have a therapeutic effect. PD 0169414, an anilinoquinazoline, is a potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4c1a143aba1d579ec730162381469f
https://doi.org/10.1007/s002800050034
https://doi.org/10.1007/s002800050034
Publikováno v:
Investigational New Drugs. 9:1-8
The antitumor activity of [SP-4-3-(R)]-[1,1-cyclobutanedicarboxylato-(2-)](2 methyl-1,4-butanediamine-N,N')platinum (CI-973) was characterized in a number of preclinical model systems. CI-973 retained substantial activity in cisplatin resistant murin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514b73363577e6d768008acdab487e17
https://doi.org/10.1007/bf00194538
https://doi.org/10.1007/bf00194538
Autor:
Patrick W. Vincent, Aneesa M. Amar, Gina H. Lu, Diane H. Boschelli, James M. Nelson, Hussein Hallak, Sylvester Klutchko, Donald J. Dykes, Laura A. Bradford, Panek Rl, Chad L. Stoner, Wayne D. Klohs, James M. Hamby, Brian G. Hartl, H. D. Hollis Showalter, Randall W. Steinkampf, Alan J. Kraker, Annette M. Doherty, Billy J. Roberts, Cynthia Shen, William L. Elliott, Terry C. Major, Tawny K. Dahring, Zhipei Wu, Denise L. Driscoll
Publikováno v:
Journal of medicinal chemistry. 41(17)
While engaged in therapeutic intervention against a number of proliferative diseases, we have discovered the 2-aminopyrido[2, 3-d]pyrimidin-7(8H)-ones as a novel class of potent, broadly active tyrosine kinase (TK) inhibitors. An efficient route was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a96247a3000b371a6bbb1cbb03279775
https://pubmed.ncbi.nlm.nih.gov/9703473
https://pubmed.ncbi.nlm.nih.gov/9703473
Autor:
Jeff W. Kampf, Billy J. Roberts, H. D. Hollis Showalter, Alan J. Kraker, James D. Hoeschele, William L. Elliott
Publikováno v:
Journal of medicinal chemistry. 37(17)
The first two analogs 5a,b of a new class of neutral large-ring square-planar Pt(II) chelate complexes of the generic structure [Pt(cis-1,4-dach)X2] were synthesized via a refined technique, structurally characterized by NMR (1H, 13C, 195Pt), FAB mas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff208385a9d2a2298186c911b13e0eb8
https://pubmed.ncbi.nlm.nih.gov/8064793
https://pubmed.ncbi.nlm.nih.gov/8064793
Autor:
Billy J. Roberts, David W. Fry, Kenneth E. Hook, Theodore J. Boritzki, Wilbur R. Leopold, Robert C. Jackson
Publikováno v:
Advances in Enzyme Regulation. 23:193-215
1. 1. CI-920 is a structurally novel, phosphate-containing polyene lactone antitumor agent isolated from a previously undescribed subspecies of Streptomyces pulveraceus cultured from a Brazilian soil sample. 2. 2. CI-920 was active against murine leu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f95a76df8d71ad7cb4694beef0836d
https://doi.org/10.1016/0065-2571(85)90048-2
https://doi.org/10.1016/0065-2571(85)90048-2
Publikováno v:
Cancer chemotherapy and pharmacology. 6(2)
Two compounds that bind to or intercalate with DNA (DNA binders), e.g., adriamycin and 'dihydroxyanthracenedione', 9,10-anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)-amino]ethyl]amino]-, dihydrochloride salt, consistently caused delayed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36ac9e23321389efacd6ce6af422818
https://pubmed.ncbi.nlm.nih.gov/6946879
https://pubmed.ncbi.nlm.nih.gov/6946879