Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Billy Chieng"'
Publikováno v:
eLife, Vol 9 (2020)
The posterior dorsomedial striatum (pDMS) is necessary for goal-directed action; however, the role of the direct (dSPN) and indirect (iSPN) spiny projection neurons in the pDMS in such actions remains unclear. In this series of experiments, we examin
Externí odkaz:
https://doaj.org/article/4e812eb4f6944b2bb00e287debb073ea
Autor:
Serena Becchi, Billy Chieng, Laura A. Bradfield, Roberto Capellán, Beatrice K. Leung, Bernard W. Balleine
The loss of neurons in parafascicular thalamus (Pf) and of their inputs to dorsomedial striatum (DMS) are associated with Lewy body disease (LBD) and Parkinson’s disease dementia (PDD) and have been linked to the effects of neuroinflammation. In ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f167a1f5f32876d6c79011a40c07b4d
https://doi.org/10.1101/2022.08.25.505358
https://doi.org/10.1101/2022.08.25.505358
Publikováno v:
European Journal of Neuroscience. 47:1159-1173
It has been recently demonstrated that predictive learning induces a persistent accumulation of delta-opioid receptors (DOPrs) at the somatic membrane of cholinergic interneurons (CINs) in the nucleus accumbens shell (Nac-S). This accumulation is req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5cffb547a8af066dc7400fddc0de7e
https://doi.org/10.1111/ejn.13750
https://doi.org/10.1111/ejn.13750
Autor:
Jesus Bertran-Gonzalez, Beatrice K. Leung, Bernard W. Balleine, Elise Pepin, Billy Chieng, Vincent Laurent, Emily Heath, Ashleigh K. Morse
Publikováno v:
Neuron. 106(5)
Predictive learning exerts a powerful influence over choice between instrumental actions. Nevertheless, how this learning is encoded in a sufficiently stable manner to influence choices that can occur much later in time is unclear. Here, we report th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97265700cdf6dfd13621ae187b8a3805
https://pubmed.ncbi.nlm.nih.gov/32240599
https://pubmed.ncbi.nlm.nih.gov/32240599
Autor:
Billy Chieng, Vincent Laurent, Elise Pepin, Jesus Bertran-Gonzalez, Bernard W. Balleine, Beatrice K. Leung, Emily Heath, Ashleigh K. Morse
Publikováno v:
SSRN Electronic Journal.
Predictive learning exerts a powerful influence over choice between instrumental actions. Nevertheless, how this learning is encoded in a sufficiently stable manner to influence choices that can occur much later in time is unclear. Here, we report th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::303d330df11337d939bb26ffee9ea11d
https://doi.org/10.2139/ssrn.3472044
https://doi.org/10.2139/ssrn.3472044
Publikováno v:
Current Biology. 26:3169-3175
Summary Extinction involves altering a previously established predictive relationship between a cue and its outcome by repeatedly presenting that cue alone. Although it is widely accepted that extinction generates some form of inhibitory learning [1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b930c2ea2a5ccfccbbbc6459136f3fa
https://doi.org/10.1016/j.cub.2016.09.021
https://doi.org/10.1016/j.cub.2016.09.021
Publikováno v:
Current biology : CB. 28(14)
The acquisition of new goal-directed actions requires the encoding of action-outcome associations. At a neural level, this encoding has been hypothesized to involve a prefronto-striatal circuit extending between the prelimbic cortex (PL) and the post
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b0776efd4db8f82ff90ad316bf1a3d5
https://pubmed.ncbi.nlm.nih.gov/30056856
https://pubmed.ncbi.nlm.nih.gov/30056856
Publikováno v:
British Journal of Pharmacology. 172:492-500
Background and Purpose Tolerance to the behavioural effects of morphine is blunted in β-arrestin-2 knockout mice, but opioid withdrawal is largely unaffected. The cellular mechanisms of tolerance have been studied in some neurons from β-arrestin-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21808b25c3a098d14fe9aaf5575e399f
https://doi.org/10.1111/bph.12673
https://doi.org/10.1111/bph.12673
Publikováno v:
The Journal of Neuroscience. 34:1358-1369
Decision-making depends on the ability to extract predictive information from the environment to guide future actions. Outcome-specific Pavlovian-instrumental transfer (PIT) provides an animal model of this process in which a stimulus predicting a pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e823014618e457e7d37ae3c2971a0111
https://doi.org/10.1523/jneurosci.4592-13.2014
https://doi.org/10.1523/jneurosci.4592-13.2014