Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Billie L. Padgett"'
Publikováno v:
Intervirology. 8:182-185
The specificity of the tumor-specific transplantation antigen (TSTA) induced by JC virus was investigated by cross protection tests in weanling hamsters. Hamsters immunized with JC virus, BK virus, or SV40 were challenged 5 weeks later with known num
Publikováno v:
Journal of Virology. 45:299-308
We cloned JC virus DNA obtained directly from brain tissue of 10 cases of progressive multifocal leukoencephalopathy and compared DNAs by restriction endonuclease mapping. Before cloning, each DNA preparation was homogeneous with respect to restricti
Autor:
N R Miller, William C. Wallen, Billie L. Padgett, Duard L. Walker, William T. London, P E McKeever
Publikováno v:
Journal of Virology. 49:848-856
The DNA from astrocytomas that developed in adult owl monkeys 16 to 36 months after intracranial inoculation with JC virus (JCV) was examined for the presence of the JCV genome by hybridization to cloned JCV DNA. The JCV genome was found to be integr
Autor:
Kenneth P. Johnson, Billie L. Padgett, John B. Penney, Kenneth H. Rand, Thomas C. Merigan, Jerry S. Wolinsky, Lucien J. Rubinstein, Duard L. Walker
Publikováno v:
Annals of Neurology. 1:458-462
Two patients with biopsy-proved progressive multifocal leukoencephalopathy (PML) were treated with near-maximal doses of adenine arabinoside (Ara-A), 18.6 and 20 mg per kilogram of body weight per day for 14 days. In both patients, clinical progressi
Autor:
Michael J. Rubino, William E. Harmon, Brian W. Grinnell, Billie L. Padgett, Paul J. Edelson, Duard L. Walker, Seymour Rosen, Alan M. Krensky
Publikováno v:
New England Journal of Medicine. 308:1192-1196
We studied viral injury to the kidney in a six-year-old boy with hyperimmunoglobulin M immunodeficiency who presented with irreversible acute renal failure and eventually died after five months of dialysis. Renal biopsy at the time of his presentatio
Characterization of Tissue Culture-induced Heterogeneity in DNAs of Independent Isolates of JC Virus
Publikováno v:
Journal of General Virology. 64:2271-2280
After several serial passages at low multiplicities of infection in primary human foetal glial cells at 37 degrees C, the DNA of prototype (MAD-1) JC virus and that of MAD-2 and MAD-3 are typically heterogeneous in size, but DNAs of MAD-4 and MAD-6 a
Autor:
Billie L. Padgett, Gabriele M. ZuRhein, W. B. Quay, Yu-Heng Ma, Duard L. Walker, John Varakis
Publikováno v:
JNCI: Journal of the National Cancer Institute. 58:123-127
Hydroxyindole-O-methyltransferase (HIOMT) (HIOMT) activity was studied and compared in 7 pineal tumors (pineocytomas) induced in vivo in Syrian hamsters after postnatal inoculation with strains of human papovavirus (JC). Levels of tumor HIOMT activit
Publikováno v:
Journal of Infectious Diseases. 133:686-690
Brain tissue from seven patients with progressive multifocal leukoencephalopathy was tested for the presence of papovaviruses. JC virus, ahuman papovavirus, was identified in all seven cases. Virus was isolated in tissue culture from extracts from ea
Publikováno v:
Journal of Virology. 32:476-482
The infectivity of JC virus DNA was demonstrated in its most permissive cell culture, primary human fetal glial cells. The amount of infectivity observed in these heterogeneous cultures varied considerably between batches of cells. Contrary to result
Publikováno v:
Journal of Infectious Diseases. 147:669-675
Tissues from 10 patients with progressive multifocal leukoencephalopathy (PML) and 14 patients without PML who were serologically positive for JC papovavirus were examined by molecular hybridization for human polyomavirus DNA sequences. Although vira