Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bill Sun"'
Autor:
Liang Liang, Bill Sun
Publikováno v:
Bioengineering, Vol 6, Iss 4, p 104 (2019)
Artificial heart valves, used to replace diseased human heart valves, are life-saving medical devices. Currently, at the device development stage, new artificial valves are primarily assessed through time-consuming and expensive benchtop tests or ani
Externí odkaz:
https://doaj.org/article/2a37aebec45e43ee8575708b141b0edb
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35331 (2012)
Hepatitis B virus encoded X antigen (HBx) is a trans-regulatory protein that alters the activity of selected transcription factors and cytoplasmic signal transduction pathways. HBx transcriptionally up-regulates the expression of a unique gene, URG11
Externí odkaz:
https://doaj.org/article/6509a4e80d194f5a8b3dc24b06a58155
Autor:
Bill Sun, Liang Liang
Publikováno v:
Bioengineering
Bioengineering, Vol 6, Iss 4, p 104 (2019)
Volume 6
Issue 4
Bioengineering, Vol 6, Iss 4, p 104 (2019)
Volume 6
Issue 4
Artificial heart valves, used to replace diseased human heart valves, are life-saving medical devices. Currently, at the device development stage, new artificial valves are primarily assessed through time-consuming and expensive benchtop tests or ani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581c1bf4dd74187d8f3f6fe81ea71b4d
https://pubmed.ncbi.nlm.nih.gov/31717333
https://pubmed.ncbi.nlm.nih.gov/31717333
Publikováno v:
Antivir Chem Chemother
Woodchuck hepatitis virus (WHV)-infected woodchucks have been used for preclinical development of drugs against hepatitis B virus (HBV). However, there is no simple in vivo model to evaluate small amounts of compounds against HBV. To develop such a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e14ba09f4abbed65e742e26154f8d79
https://doi.org/10.1177/095632020701800405
https://doi.org/10.1177/095632020701800405
Autor:
Jingbo Pan, Alexey A. Matskevich, Bill Sun, David S. Strayer, Jie Liu, Mark A. Feitelson, Michael A. Gerber, Xiaoping Yan, Marcy Clayton
Publikováno v:
Journal of Cellular Physiology. 201:447-458
HepG2 cells stably transfected with a full-length, infectious hepatitis C virus (HCV) cDNA demonstrated consistent replication of HCV for more than 3 years. Intracellular minus strand HCV RNA was present. Minus strand synthesis was NS5B dependent, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0702785ab0703452171047e53287097d
https://doi.org/10.1002/jcp.20083
https://doi.org/10.1002/jcp.20083
Autor:
Mark A. Feitelson, Bill Sun, Frank H. Michaels, Judith L. Morgan, Linda D. Siracusa, Claire E. Perchonock, J. Larkin, Marcy Clayton
Publikováno v:
Nature Medicine. 5:907-912
A model for hepatitis B virus-associated chronic liver disease has been made using cloned hepatitis B virus DNA as a transgene in a severe combined immunodeficient host. These mice consistently support virus gene expression and replication. After ado
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e315fd29f85a8144fb9d19ab9b0ef511
https://doi.org/10.1038/11347
https://doi.org/10.1038/11347
Autor:
Bill Sun, Marcia M. Clayton, Zhaorui Lian, Alla Arzumanyan, Helena M. G. P. V. Reis, Mark A. Feitelson
Publikováno v:
Molecular Pathology Library ISBN: 9781441971067
Chronic hepatitis B virus (HBV) infection is the most important etiologic agent of hepatocellular carcinoma (HCC) worldwide. This is remarkable, considering that the virus consists of a DNA genome that is only 3.2 kb in size and encodes proteins from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::767aeb27e7fca378db01c104cc153862
https://doi.org/10.1007/978-1-4419-7107-4_37
https://doi.org/10.1007/978-1-4419-7107-4_37
Publikováno v:
Methods in enzymology. 392
The rapid increase in the study of small interfering RNA (siRNA) as a means to decrease expression of targeted genes has led to concerns about possible unexpected consequences of constitutive siRNA expression. We therefore devised a conditional siRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d83f934168b8f5e6222ee0ad503f111
https://pubmed.ncbi.nlm.nih.gov/15644185
https://pubmed.ncbi.nlm.nih.gov/15644185
The rapid increase in the study of small interfering RNA (siRNA) as a means to decrease expression of targeted genes has led to concerns about possible unexpected consequences of constitutive siRNA expression. We therefore devised a conditional siRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5bdf781dffd6157de3007d499b1e14b
https://doi.org/10.1016/s0076-6879(04)92014-9
https://doi.org/10.1016/s0076-6879(04)92014-9
Publikováno v:
Oncogene. 21(16)
The development of hepatocellular carcinoma (HCC) is a multistep process associated with changes in host gene expression, some of which correlate with the appearance and progression of tumor. Preneoplastic changes in gene expression result from alter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fc476c882a8e828112febf93170028
https://pubmed.ncbi.nlm.nih.gov/11971194
https://pubmed.ncbi.nlm.nih.gov/11971194