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pro vyhledávání: '"Bill Pham"'
Autor:
Bill Pham, Ziju Cheng, Daniel Lopez, Richard J. Lindsay, David Foutch, Rily T. Majors, Tongye Shen
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The receptor RORγ belongs to the nuclear receptor superfamily that senses small signaling molecules and regulates at the gene transcription level. Since RORγ has a high basal activity and plays an important role in immune responses, inhibitors targ
Externí odkaz:
https://doaj.org/article/2f6a538dd86b4cf2999bfe9c1ebee9d2
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3599-3608 (2021)
Network analysis has emerged as a powerful tool for examining structural biology systems. The spatial organization of the components of a biomolecular structure has been rendered as a graph representation and analyses have been performed to deduce th
Externí odkaz:
https://doaj.org/article/e908afa4a76f44d7b954262f8b82ff97
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3599-3608 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Network analysis has emerged as a powerful tool for examining structural biology systems. The spatial organization of the components of a biomolecular structure has been rendered as a graph representation and analyses have bee
Network analysis has emerged as a powerful tool for examining structural biology systems. The spatial organization of the components of a biomolecular structure has been rendered as a graph representation and analyses have bee
Publikováno v:
Journal of chemical information and modeling. 59(12)
Constitutive androstane receptor (CAR) is a nuclear hormone receptor that primarily functions in sensing and metabolizing xenobiotics. The basal activity of this receptor is relatively high, and CAR is deemed active in the absence of ligand. The (ove
Publikováno v:
Biochemistry. 58(6)
Proteins forming dimers or larger complexes can be strongly influenced by their effector-binding status. We investigated how the effector-binding event is coupled with interface formation via computer simulations, and we quantified the correlation of