Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Bill Kwan-Wai Chan"'
Autor:
Han Wang, Qi Xu, Heng Heng, Wenxing Zhao, Hongyuhang Ni, Kaichao Chen, Bill Kwan Wai Chan, Yang Tang, Miaomiao Xie, Mingxiu Peng, Edward Wai Chi Chan, Guan Yang, Sheng Chen
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105340- (2024)
Summary: Background: The continuous emergence of multidrug-resistant (MDR) Acinetobacter baumannii (Ab) strains poses further challenges in its control and clinical management. It is necessary to decipher the mechanisms underlying the high mortality
Externí odkaz:
https://doaj.org/article/877794228a95425d93ea26b6abe71772
Publikováno v:
Genes and Diseases, Vol 12, Iss 1, Pp 101236- (2025)
Externí odkaz:
https://doaj.org/article/79ebe2ea799d4b798dd113648cf5aba0
Autor:
Hongyuhang Ni, Bill Kwan-Wai Chan, Lianwei Ye, Haoze Wu, Heng Heng, Qi Xu, Kaichao Chen, Rex Yan-Chu Cheung, Han Wang, Edward Wai-Chi Chan, Fuyong Li, Sheng Chen
Publikováno v:
Pharmacological Research, Vol 206, Iss , Pp 107254- (2024)
Gut damage during carbapenem-resistant and hypervirulent Klebsiella pneumoniae (CR-HvKP) infection is associated with a death risk. Understanding the mechanisms by which CR-HvKP causes intestinal damage and gut microbiota alteration, and the impact o
Externí odkaz:
https://doaj.org/article/1adb59b958f44b5bb7d7f75faa794330
Autor:
Xuemei Yang, Man-Yee Man, Heng Heng, Bill Kwan-Wai Chan, Qiao Hu, Edward Wai-Chi Chan, Hoi-Ping Shum, Sheng Chen
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 104998- (2024)
Summary: Background: The epidemiological features of the Klebsiella pneumoniae causing bloodstream infections in Hong Kong and their potential threats to human health remained unknown. Methods: K. pneumoniae strains collected from four hospitals in H
Externí odkaz:
https://doaj.org/article/7c5617d16b734c64b1d3c312d7bdd914
Autor:
Han Wang, Qi Xu, Kaichao Chen, Bill Kwan Wai Chan, Lianwei Ye, Xuemei Yang, Miaomiao Xie, Xiaobo Liu, Hongyuhang Ni, Edward Wai Chi Chan, Sheng Chen
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT A plasmid that harbored the virulence factors highly like those of the virulence plasmid commonly found in clinical hypervirulent Klebsiella pneumoniae strains was detected in a foodborne Escherichia coli strain EC1108 and designated p1108-I
Externí odkaz:
https://doaj.org/article/7d26902390694c439e43432e5592987b
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Coexistence of oqxAB and aac(6′)-Ib-cr is often associated with the expression of fluoroquinolone resistance in Salmonella. The actual role of the plasmid-borne oqxAB gene and its regulatory mechanism compared to its chromosomally encoded
Externí odkaz:
https://doaj.org/article/d45ebf4338364a888873b00053ed3829
Autor:
Kathy Hiu Laam Po, Hoi Yee Chow, Qipeng Cheng, Bill Kwan‐wai Chan, Xin Deng, Shuping Wang, Edward Wai Chi Chan, Hang‐Kin Kong, Kin Fai Chan, Xuechen Li, Sheng Chen
Publikováno v:
Natural Sciences, Vol 1, Iss 2, Pp n/a-n/a (2021)
Abstract Daptomycin, as a lipopeptide antibiotic, exhibits high potency in the treatment of infections caused by clinically relevant drug‐resistant Gram‐positive pathogens, such as methicillin‐resistant Staphylococcus aureus and vancomycin‐re
Externí odkaz:
https://doaj.org/article/a6bad123c9a94b91940a8c8acc3bb816
Autor:
Rui Zhang, Chris Y. Cheung, Sang-Uk Seo, Hang Liu, Lakhansing Pardeshi, Koon Ho Wong, Larry M. C. Chow, Mary P. Chau, Yixiang Wang, Ah Ra Lee, Woon Yong Kwon, Sheng Chen, Bill Kwan-wai Chan, Kenneth Wong, Richard K. W. Choy, Ben C. B. Ko
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Macrophages play an important role in the host defense mechanism. In response to infection, macrophages activate a genetic program of pro-inflammatory response to kill any invading pathogen, and initiate an adaptive immune response. We have identifie
Externí odkaz:
https://doaj.org/article/73c5cecb1e1348179fadfe22111b3410
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Acinetobacter baumannii is an important clinical pathogen which often causes fatal infections among seriously ill patients. Treatment options for managing infections caused by this organism have become limited as a result of emergence of carbapenem r
Externí odkaz:
https://doaj.org/article/daa6a17f683a4c7abf00fe8c88256c7e
Autor:
Hang-kin Kong, Hoi Yee Chow, Xuechen Li, Kathy Hiu Laam Po, Shuping Wang, Bill Kwan-wai Chan, Qipeng Cheng, Kin-Fai Chan, Edward Chan, Sheng Chen, Xin Deng
Publikováno v:
Natural Sciences, Vol 1, Iss 2, Pp n/a-n/a (2021)
Daptomycin, as a lipopeptide antibiotic, exhibits high potency in the treatment of infections caused by clinically relevant drug‐resistant Gram‐positive pathogens, such as methicillin‐resistant Staphylococcus aureus and vancomycin‐resistant E