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pro vyhledávání: '"Bill Hakim"'
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-14 (2022)
Abstract Background Insulin-like growth factor-1 (IGF-1) has the potential to be used for osteoarthritis (OA) treatment but has not been evaluated in clinics yet owing to toxicity concerns. It suffers from short intra-joint residence time and a lack
Externí odkaz:
https://doaj.org/article/75851a2c13c141f7a4590b91860a16bc
Autor:
Armin Vedadghavami, Tengfei He, Chenzhen Zhang, Salima M. Amiji, Bill Hakim, Ambika G. Bajpayee
Publikováno v:
Acta biomaterialia. 151
Charge-based drug delivery has proven to be effective for targeting negatively charged cartilage for the treatment of osteoarthritis. Cartilage is surrounded by synovial fluid (SF), which is comprised of negatively charged hyaluronic acid and hydroph
Background. Insulin-like growth factor-1 (IGF-1) has the potential to be used for osteoarthritis (OA) treatment but has not been evaluated in clinics yet owing to toxicity concerns. It suffers from short intra-joint residence time and a lack of carti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fddfae2d22746f5890eaf1354a700aba
https://doi.org/10.21203/rs.3.rs-1474872/v1
https://doi.org/10.21203/rs.3.rs-1474872/v1