Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Bill H. Chang"'
Autor:
Juan Carlos Rivera-Mulia, Takayo Sasaki, Claudia Trevilla-Garcia, Naoto Nakamichi, David J. H.F. Knapp, Colin A. Hammond, Bill H. Chang, Jeffrey W. Tyner, Meenakshi Devidas, Jared Zimmerman, Kyle N. Klein, Vivek Somasundaram, Brian J. Druker, Tanja A. Gruber, Amnon Koren, Connie J. Eaves, David M. Gilbert
Publikováno v:
Blood Advances, Vol 3, Iss 21, Pp 3201-3213 (2019)
Abstract: Human B-cell precursor acute lymphoid leukemias (BCP-ALLs) comprise a group of genetically and clinically distinct disease entities with features of differentiation arrest at known stages of normal B-lineage differentiation. We previously s
Externí odkaz:
https://doaj.org/article/813e5445336443a09e50cbf90d7c35a2
Autor:
Jina, Park, Devlynne Sasha, Ondusko, Bill H, Chang, Emily A, Edwards, Sylvia, Doan, Ken, Gatter, Ibrahim, Hajjali, Amanda, Kim
Publikováno v:
NeoReviews. 23:e861-e868
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a5820bba15f39c4c005c80e16b55ef
https://doi.org/10.1542/neo.23-12-e861
https://doi.org/10.1542/neo.23-12-e861
Autor:
Stephen E. Kurtz, Christopher A. Eide, Andy Kaempf, Nicola Long, Daniel Bottomly, Olga Nikolova, Brian J. Druker, Shannon K. McWeeney, Bill H. Chang, Jeffrey W. Tyner, Anupriya Agarwal
Publikováno v:
Blood Advances. 6:3062-3067
Using ex vivo drug screening of primary patient specimens, we identified the combination of the p38 MAPK inhibitor doramapimod (DORA) with the BCL2 inhibitor venetoclax (VEN) as demonstrating broad, enhanced efficacy compared with each single agent a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5c5b23cccbc67a93f4c286567a32c5
https://doi.org/10.1182/bloodadvances.2021006307
https://doi.org/10.1182/bloodadvances.2021006307
Autor:
Olivia M. Lucero, Ji-Ann Lee, Jenna Bowman, Kara Johnson, Gopal Sapparapu, John K. Thomas, Guang Fan, Bill H. Chang, Karina Thiel-Klare, Christopher A. Eide, Craig Okada, Mike Palazzolo, Evan Lind, Yoko Kosaka, Brian J. Druker, Nicholas Lydon, Peter M. Bowers
Publikováno v:
Clinical Cancer Research.
Purpose: Targeted therapeutics are a goal of medicine. Methods for targeting T-cell lymphoma lack specificity for the malignant cell, leading to elimination of healthy cells. The T-cell receptor (TCR) is designed for antigen recognition. T-cell malig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0406b605cf292eed569ab610404cdc6a
https://doi.org/10.1158/1078-0432.ccr-22-0906
https://doi.org/10.1158/1078-0432.ccr-22-0906
Autor:
Jeffrey W. Tyner, Shannon K McWeeney, Bill H. Chang, Brian J. Druker, Alexey V. Danilov, Cristina E. Tognon, Mara Rosenberg, Sunil K. Joshi, Amanda d'Almeida, Rachel Culp-Hill, Angelo D'Alessandro, Courtney L. Jones, Tingting Liu, Olga Nikolova, Stephen E. Kurtz, Tamilla Nechiporuk
Response to entrectinib on AML patient samples with TP53 mutations in vivo and expression of RUNX1 isoforms in AML patient samples and MOLM13 parental and CRISPR modified cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56068364d0bde7917ab77cadf8448eab
https://doi.org/10.1158/2159-8290.22536124.v1
https://doi.org/10.1158/2159-8290.22536124.v1
Supplementary Table 8 from TYK2–STAT1–BCL2 Pathway Dependence in T-cell Acute Lymphoblastic Leukemia
Autor:
A. Thomas Look, Brian J. Druker, Louis M. Staudt, Andrew P. Weng, Catriona H.M. Jamieson, Nathanael S. Gray, Mathias Müller, Richard Moriggl, Ross L. Levine, Donna S. Neuberg, Michelle A. Kelliher, Jessica Tatarek, Yebin Ahn, Maria Kleppe, Yandan Yang, Wenjun Zhou, Angela G. Fleischman, Wenxue Ma, Arla Yost, Bill H. Chang, Jason Glover, Vu N. Ngo, Alejandro Gutierrez, Jeffrey W. Tyner, Takaomi Sanda
XLSX file - 24K, PCR Primer sequences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae008c7ad8c7be73a678ff7d8315a28b
https://doi.org/10.1158/2159-8290.22528985.v1
https://doi.org/10.1158/2159-8290.22528985.v1
Autor:
Jeffrey W. Tyner, Shannon K McWeeney, Bill H. Chang, Brian J. Druker, Alexey V. Danilov, Cristina E. Tognon, Mara Rosenberg, Sunil K. Joshi, Amanda d'Almeida, Rachel Culp-Hill, Angelo D'Alessandro, Courtney L. Jones, Tingting Liu, Olga Nikolova, Stephen E. Kurtz, Tamilla Nechiporuk
Complete methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01469889e6c7cd5bc22844d7ac585f37
https://doi.org/10.1158/2159-8290.22536121.v1
https://doi.org/10.1158/2159-8290.22536121.v1
Autor:
A. Thomas Look, Brian J. Druker, Louis M. Staudt, Andrew P. Weng, Catriona H.M. Jamieson, Nathanael S. Gray, Mathias Müller, Richard Moriggl, Ross L. Levine, Donna S. Neuberg, Michelle A. Kelliher, Jessica Tatarek, Yebin Ahn, Maria Kleppe, Yandan Yang, Wenjun Zhou, Angela G. Fleischman, Wenxue Ma, Arla Yost, Bill H. Chang, Jason Glover, Vu N. Ngo, Alejandro Gutierrez, Jeffrey W. Tyner, Takaomi Sanda
PDF file - 113K, Bcl2 protein expression in wild-type and Tyk2 knockout mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ba7b281b9141533ece67a5eca0d6a5
https://doi.org/10.1158/2159-8290.22529012
https://doi.org/10.1158/2159-8290.22529012
Autor:
A. Thomas Look, Brian J. Druker, Louis M. Staudt, Andrew P. Weng, Catriona H.M. Jamieson, Nathanael S. Gray, Mathias Müller, Richard Moriggl, Ross L. Levine, Donna S. Neuberg, Michelle A. Kelliher, Jessica Tatarek, Yebin Ahn, Maria Kleppe, Yandan Yang, Wenjun Zhou, Angela G. Fleischman, Wenxue Ma, Arla Yost, Bill H. Chang, Jason Glover, Vu N. Ngo, Alejandro Gutierrez, Jeffrey W. Tyner, Takaomi Sanda
PDF file - 74K, Knockdown efficiency and BCL2 expression in JURKAT cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6781de9ba400c8ef69fbe3a4df74155e
https://doi.org/10.1158/2159-8290.22529027
https://doi.org/10.1158/2159-8290.22529027
Autor:
Jeffrey W. Tyner, Shannon K McWeeney, Bill H. Chang, Brian J. Druker, Alexey V. Danilov, Cristina E. Tognon, Mara Rosenberg, Sunil K. Joshi, Amanda d'Almeida, Rachel Culp-Hill, Angelo D'Alessandro, Courtney L. Jones, Tingting Liu, Olga Nikolova, Stephen E. Kurtz, Tamilla Nechiporuk
Dose response curve analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2b5c702ee40ea69e999235e9edf717
https://doi.org/10.1158/2159-8290.22536133.v1
https://doi.org/10.1158/2159-8290.22536133.v1