Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Bill G. Mahlandt"'
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 48:403-411
The safety and immunogenicity of Candid #1, a live-attenuated Junin virus vaccine, were evaluated in rhesus macaques. Candid #1 was inoculated subcutaneously in graded doses ranging from 16 to 127,200 plaque-forming units (PFU) into four groups of fi
Publikováno v:
Intervirology. 34:154-163
The protective efficacy of Candid No. 1, a live-attenuated vaccine against Argentine hemorrhagic fever (AHF), was evaluated in non-human primates. Twenty rhesus macaques immunized 3 months previously with graded doses of Candid No. 1 (16-127, 000 PFU
Publikováno v:
Antimicrobial Agents and Chemotherapy. 32:1304-1309
Junin virus-infected rhesus macaques received prophylactic and therapeutic ribavirin to assess the potential of this drug for treating humans with Argentine hemorrhagic fever. When ribavirin was administered intramuscularly at the time of experimenta
Publikováno v:
American Journal of Epidemiology. 60:15-26
Autor:
Richard C. Carter, Bill G. Mahlandt, Francis J. Weirether, Jerry S. Walker, Michael D. Orlando, Ralph E. Lincoln, Frederick Klein
Publikováno v:
Applied Microbiology. 17:427-434
Studies were conducted on the interaction of various parameters which affect the storage stability and growth potential of liquid cultures of Pasteurella tularensis live vaccine strain (LVS) and Rift Valley fever virus Van Wyk strain (RVFV). Storage
Publikováno v:
The Journal of Immunology. 91:431-437
Summary The effects of anthrax immunization on the serum antibody titer and the immunity index were compared for guinea pigs and rats immunized by two protocols. An association between the two measures could not be detected in either species of anima
Autor:
James A. Vick, Norman S. Remmele, Jerry S. Walker, Bill G. Mahlandt, Frederick Klein, Ralph E. Lincoln
Publikováno v:
Journal of Infectious Diseases. 118:104-113
Administration of anthrax toxin via the cerebrospinal fluid demonstrates positively that the toxin alters the body's physiology, primarily via the central nervous system, and kills by terminal anoxia mediated by the central nervous system. The use of
Autor:
Frederick Klein, Norman S. Remmele, Jerry S. Walker, Ralph E. Lincoln, James P. Dobbs, Bill G. Mahlandt
Publikováno v:
Journal of Infectious Diseases. 118:97-103
Anthrax toxin depressed the cerebral cortical electrical activity of both anesthetized and non anesthetized monkeys and anesthetized chimpanzees. Recordings on a physiograph recorder revealed changes in electrocardiogram and hypoxic hypertension that
Publikováno v:
Archives of Biochemistry and Biophysics. 71:31-51
1. 1. The recovery of Pasteurella tularensis cells suspended in a solution of gelatin-saline depended on ( a ) the rate of cooling, ( b ) the minimum temperature attained, ( c ) the time at a given temperature, and ( d ) the rate of subsequent warmin
Autor:
Kenneth J. Hendrix, Frederick Klein, David F. Fitzpatrick, William J. Jones, Jerry S. Walker, James P. Dobbs, Bill G. Mahlandt, Ralph E. Lincoln
Publikováno v:
Journal of Infectious Diseases. 116:123-138
The disease syndromes produced by both Bacillus anthracis organisms and by sterile in vitro toxins are orderly and predictable. Most of the signs and changes in the blood cellular, and gaseous elements occur late in the septicemic phase of disease, w