Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Biljana Culjkovic"'
eIF4E orchestrates mRNA processing, RNA export and translation to modify specific protein production
Publikováno v:
Nucleus, Vol 15, Iss 1 (2024)
The eukaryotic translation initiation factor eIF4E acts as a multifunctional factor that simultaneously influences mRNA processing, export, and translation in many organisms. Its multifactorial effects are derived from its capacity to bind to the met
Externí odkaz:
https://doaj.org/article/cc117cf3379445b7b80b015946b17d39
Autor:
Sarit Assouline, Jadwiga Gasiorek, Julie Bergeron, Caroline Lambert, Biljana Culjkovic-Kraljacic, Eftihia Cocolakis, Chadi Zakaria, David Szlachtycz, Karen Yee, Katherine L.B. Borden
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Drug resistance underpins poor outcomes in many malignancies including refractory and relapsed acute myeloid leukemia (R/R AML). Glucuronidation is a common mechanism of drug inactivation impacting many AML therapies, e.g., cytarabine, decitabine, az
Externí odkaz:
https://doaj.org/article/826412a4b7274b2ba463c6ba484f9565
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Traditionally, cancer is viewed as a disease driven by genetic mutations and/or epigenetic and transcriptional dysregulation. While these are undoubtedly important drivers, many recent studies highlight the disconnect between the proteome and the gen
Externí odkaz:
https://doaj.org/article/39628735a08f49af809da637a20e5e39
Autor:
Hiba Ahmad Zahreddine, Biljana Culjkovic-Kraljacic, Audrey Emond, Filippa Pettersson, Ronald Midura, Mark Lauer, Sonia Del Rincon, Valbona Cali, Sarit Assouline, Wilson H Miller, Vincent Hascall, Katherine LB Borden
Publikováno v:
eLife, Vol 6 (2017)
The microenvironment provides a functional substratum supporting tumour growth. Hyaluronan (HA) is a major component of this structure. While the role of HA in malignancy is well-defined, the mechanisms driving its biosynthesis in cancer are poorly u
Externí odkaz:
https://doaj.org/article/347003db749b4cfea541aa4f5080caa2
Autor:
Biljana Culjkovic-Kraljacic, Aurélie Baguet, Laurent Volpon, Abdellatif Amri, Katherine L.B. Borden
Publikováno v:
Cell Reports, Vol 2, Iss 2, Pp 207-215 (2012)
The eukaryotic translation initiation factor eIF4E is a potent oncogene that promotes the nuclear export and translation of specific transcripts. Here, we have discovered that eIF4E alters the cytoplasmic face of the nuclear pore complex (NPC), which
Externí odkaz:
https://doaj.org/article/ff886545fa334171ac500bbbed49f0e7
Autor:
Sarit Assouline, Biljana Culjkovic-Kraljacic, Julie Bergeron, Stephen Caplan, Eftihia Cocolakis, Caroline Lambert, Cara J. Lau, Hiba Ahmad Zahreddine, Wilson H. Miller, Katherine L. B. Borden
Publikováno v:
Haematologica, Vol 100, Iss 1 (2015)
Externí odkaz:
https://doaj.org/article/4b334c17ad364ea895bc5372c0d308dd
Autor:
Leandro Cerchietti, Ari Melnick, John P. Leonard, Giorgio Inghirami, Katherine L. Borden, Randy D. Gascoyne, Lucy A. Godley, Fabrizio Tabbo, Amy Chadburn, Rita Shaknovich, Micheal Leser, Sarah Wyman, David W. Scott, Biljana Culjkovic, Aparna Vasanthakumar, Samprit Banerjee, Matthias Kormaksson, Peter Martin, Wayne Tam, Rebecca L. Elstrom, ShaoNing Yang, Thomas Clozel
Figure S5 - PDF file 224K, Toxicity studies in mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12229b5cf6bc86e4efd6d0e0b8d98300
https://doi.org/10.1158/2159-8290.22530860
https://doi.org/10.1158/2159-8290.22530860
Autor:
Leandro Cerchietti, Ari Melnick, John P. Leonard, Giorgio Inghirami, Katherine L. Borden, Randy D. Gascoyne, Lucy A. Godley, Fabrizio Tabbo, Amy Chadburn, Rita Shaknovich, Micheal Leser, Sarah Wyman, David W. Scott, Biljana Culjkovic, Aparna Vasanthakumar, Samprit Banerjee, Matthias Kormaksson, Peter Martin, Wayne Tam, Rebecca L. Elstrom, ShaoNing Yang, Thomas Clozel
Figures S7, S8 and S9 - PDF file 206K, SMAD1 expression in patients and functional experiments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca549b750f9d6f63af947e11464c660
https://doi.org/10.1158/2159-8290.22530851
https://doi.org/10.1158/2159-8290.22530851
Autor:
Leandro Cerchietti, Ari Melnick, John P. Leonard, Giorgio Inghirami, Katherine L. Borden, Randy D. Gascoyne, Lucy A. Godley, Fabrizio Tabbo, Amy Chadburn, Rita Shaknovich, Micheal Leser, Sarah Wyman, David W. Scott, Biljana Culjkovic, Aparna Vasanthakumar, Samprit Banerjee, Matthias Kormaksson, Peter Martin, Wayne Tam, Rebecca L. Elstrom, ShaoNing Yang, Thomas Clozel
Supplementary Methods - PDF file 100K, Reagents, gene expression profiling, RT-PCR, mice studies, clinical trial, patient samples, ex vivo treatments, immunohistochemistry and statistical analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2326ec3a1d30f923d31bcbe2ba3c981c
https://doi.org/10.1158/2159-8290.22530845.v1
https://doi.org/10.1158/2159-8290.22530845.v1
Table S2 from Mechanism-Based Epigenetic Chemosensitization Therapy of Diffuse Large B-Cell Lymphoma
Autor:
Leandro Cerchietti, Ari Melnick, John P. Leonard, Giorgio Inghirami, Katherine L. Borden, Randy D. Gascoyne, Lucy A. Godley, Fabrizio Tabbo, Amy Chadburn, Rita Shaknovich, Micheal Leser, Sarah Wyman, David W. Scott, Biljana Culjkovic, Aparna Vasanthakumar, Samprit Banerjee, Matthias Kormaksson, Peter Martin, Wayne Tam, Rebecca L. Elstrom, ShaoNing Yang, Thomas Clozel
Table S2 - PDF file 62K, Genes hypermethylated and repressed in doxorubicin resistant cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d7982bda9ee4ee2866f7c05b2d8894
https://doi.org/10.1158/2159-8290.22530839.v1
https://doi.org/10.1158/2159-8290.22530839.v1