Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Biljana Blagojevic"'
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Background Aerobic glycolysis, discovered by Otto Warburg, is a hallmark of cancer metabolism even though not yet fully understood. The low activity of the cancerous pyruvate kinase isozyme (M2) is thought to play an important role by facili
Externí odkaz:
https://doaj.org/article/9cc2a292ae774d3891c40b5511b6ff7f
Publikováno v:
Cells, Vol 11, Iss 23, p 3863 (2022)
Targeting cancer metabolism has become one of the strategies for a rational anti-tumor therapy. However, cellular plasticity, driven by a major regulator of cellular growth and metabolism, mTORC1, often leads toward treatment resistance. Sestrin2, a
Externí odkaz:
https://doaj.org/article/8b0cce433eeb4b6a9d7a6c9e656da273
Autor:
Zeribe Chike Nwosu, Weronika Piorońska, Nadia Battello, Andreas David Zimmer, Bedair Dewidar, Mei Han, Sharon Pereira, Biljana Blagojevic, Darko Castven, Verodia Charlestin, Pavlo Holenya, Julia Lochead, Carolina De La Torre, Norbert Gretz, Peter Sajjakulnukit, Li Zhang, Matthew H. Ward, Jens U. Marquardt, Marina Pasca di Magliano, Costas A. Lyssiotis, Jonathan Sleeman, Stefan Wölfl, Matthias Philip Ebert, Christoph Meyer, Ute Hofmann, Steven Dooley
Publikováno v:
EBioMedicine, Vol 54, Iss , Pp - (2020)
Background: The extracellular signal-regulated kinase (ERK) pathway regulates cell growth, and is hyper-activated and associated with drug resistance in hepatocellular carcinoma (HCC). Metabolic pathways are profoundly dysregulated in HCC. Whether an
Externí odkaz:
https://doaj.org/article/383d5f40c0a84df0afc5bf27b396bda2
Autor:
Mohamed A. Abu el Maaty, Yasamin Dabiri, Fadi Almouhanna, Biljana Blagojevic, Jannick Theobald, Michael Büttner, Stefan Wölfl
Publikováno v:
Cancer & Metabolism, Vol 6, Iss 1, Pp 1-18 (2018)
Abstract Background We have previously identified 1,25-dihydroxyvitamin D3 [1,25(OH)2D3], the bioactive form of vitamin D3, as a potent regulator of energy-utilization and nutrient-sensing pathways in prostate cancer cells. In the current study, we i
Externí odkaz:
https://doaj.org/article/a3cd4fea2f9942a9bc7fc598ae137830
Autor:
Jana Tegethoff, Roland Bischoff, Sawsan Saleh, Biljana Blagojevic, Karl-Heinz Merz, Xinlai Cheng
Publikováno v:
Molecules, Vol 22, Iss 9, p 1546 (2017)
Indirubin is an active component of the herbal ingredient ‘Danggui Longhui wan’, which was used for the treatment of inflammation and chronic myeloid leukemia in China. The recent study showed its derivative methylisoindigo (also known as meisoin
Externí odkaz:
https://doaj.org/article/c9bdeaa6ba6d4cff926f7a06a8de2409
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-17 (2021)
Cancer & Metabolism
Cancer & Metabolism
Background Aerobic glycolysis, discovered by Otto Warburg, is a hallmark of cancer metabolism even though not yet fully understood. The low activity of the cancerous pyruvate kinase isozyme (M2) is thought to play an important role by facilitating th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1682c37ad2d31bb92b4527a9d31cc0ef
https://doaj.org/article/9cc2a292ae774d3891c40b5511b6ff7f
https://doaj.org/article/9cc2a292ae774d3891c40b5511b6ff7f
Autor:
Shahrouz Ghafoory, Yasamin Dabiri, Xinlai Cheng, Jun Zhou, Mukaddes Altinbay, Biljana Blagojevic, Anna Seidel, Ivan Đikić, Stefan Wölfl, Stefanie Reuter, Mohammad Golriz, Kang Han, Rodrigo A. Gama-Brambila, Arianeb Mehrabi
Publikováno v:
The Journal of cell biology. 221(1)
Transforming growth factor β (TGF-β) signaling plays a fundamental role in metazoan development and tissue homeostasis. However, the molecular mechanisms concerning the ubiquitin-related dynamic regulation of TGF-β signaling are not thoroughly und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19145a3edd487376f9dd7bc078068398
https://pubmed.ncbi.nlm.nih.gov/34860252
https://pubmed.ncbi.nlm.nih.gov/34860252
Autor:
Verodia Charlestin, Andreas Zimmer, Biljana Blagojevic, Peter Sajjakulnukit, Marina Pasca di Magliano, Nadia Battello, Norbert Gretz, Bedair Dewidar, Stefan Wölfl, Zeribe C. Nwosu, Matthew H. Ward, Jens U. Marquardt, Steven Dooley, Jonathan P. Sleeman, Ute Hofmann, S Pereira, Mei Han, Weronika Piorońska, Carolina De La Torre, Matthias P. Ebert, Pavlo Holenya, Costas A. Lyssiotis, D Castven, Julia Lochead, Christoph Meyer, Li Zhang
Publikováno v:
EBioMedicine, Vol 54, Iss, Pp-(2020)
EBioMedicine
EBioMedicine, 54, Art.Nr.: 102699
EBioMedicine
EBioMedicine, 54, Art.Nr.: 102699
Background: The extracellular signal-regulated kinase (ERK) pathway regulates cell growth, and is hyper-activated and associated with drug resistance in hepatocellular carcinoma (HCC). Metabolic pathways are profoundly dysregulated in HCC. Whether an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd53158ee2d8d77ac5780bb8c2de36c
http://www.sciencedirect.com/science/article/pii/S2352396420300748
http://www.sciencedirect.com/science/article/pii/S2352396420300748
Autor:
Yasamin, Dabiri, Alice, Schmid, Jannick, Theobald, Biljana, Blagojevic, Wojciech, Streciwilk, Ingo, Ott, Stefan, Wölfl, Xinlai, Cheng
Publikováno v:
International Journal of Molecular Sciences
Volume 19
Issue 12
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3964 (2018)
Volume 19
Issue 12
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3964 (2018)
The p38 MAPK pathway is known to influence the anti-tumor effects of several chemotherapeutics, including that of organometallic drugs. Previous studies have demonstrated the important role of p38 both as a regulator and a sensor of cellular reactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::567c4e1237954b223d5b730219e8de40
Autor:
Cheng, Jana Tegethoff, Roland Bischoff, Sawsan Saleh, Biljana Blagojevic, Karl-Heinz Merz, Xinlai
Publikováno v:
Molecules; Volume 22; Issue 9; Pages: 1546
Indirubin is an active component of the herbal ingredient ‘Danggui Longhui wan’, which was used for the treatment of inflammation and chronic myeloid leukemia in China. The recent study showed its derivative methylisoindigo (also known as meisoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::8665be9fab2d8e34be14f9e561ee3d39