Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Bilgesu Onur, Sucu"'
Autor:
Damla Uludağ, Sadık Bay, Bilgesu Onur Sucu, Özgecan Şavluğ İpek, Thomas Mohr, Mustafa Güzel, Nihal Karakaş
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Change in the energy metabolism of cancer cells, which display significant differences compared to normal cells, is a rising phenomenon in developing new therapeutic approaches against cancers. One of the metabolic enzymes, hexokinase-II (HK-II) is i
Externí odkaz:
https://doaj.org/article/2f2e98f9bf9a49a594df53503809c75d
Autor:
Zeynep Islek, Mehmet Hikmet Ucisik, Elif Keskin, Bilgesu Onur Sucu, Ana G. Gomes‐Alves, Ana M. Tomás, Mustafa Guzel, Fikrettin Sahin
Publikováno v:
Frontiers in Nanotechnology, Vol 3 (2022)
Among bisnaphthalimidopropyl (BNIP) derivatives, BNIPDaoct and BNIPDanon recently came forward with antileishmanial activities beyond the standard, commercialized antileishmanial therapies. However, high-level toxicity on macrophages plus poor aqueou
Externí odkaz:
https://doaj.org/article/54f7b438222243a49b7776d066771ff6
Autor:
Elif Beyza Koc, Bilgesu Onur Sucu
A series of novel 1,3,5-trisubstituted-1,2,4-triazole derivatives were successfully synthesized from the starting materials of caffeic acid (CA) and ferulic acid (FA) in moderate to good yields (45-71 %). All novel compounds were screened for antipro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738aa52ff9eb546492e5c62ddc2bf9d0
https://hdl.handle.net/20.500.12511/10975
https://hdl.handle.net/20.500.12511/10975
Publikováno v:
Journal of Molecular Structure. 1281:135114
In order to develop drugs against cancer, which is one of the deadliest diseases in the world, hybridizing structures with known anticancer activity can provide a dual activity for the treatment of cancer cases. For this purpose, a series of novel hy
Autor:
Bilgesu Onur Sucu
Imidazo[1,2-a]pyridine cores have increasing importance in the pharmaceutical industry with their wide range pharmacological activities. In this study, two series of imidazopyridine derivatives were synthesized. It was planned to integrate the pyrimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ac7392aa75272c097aa4bdfdb53e49
https://hdl.handle.net/20.500.12511/9967
https://hdl.handle.net/20.500.12511/9967
Autor:
Bilgesu Onur Sucu, Elif Beyza Koc, Ozgecan Savlug Ipek, Afranur Mirat, Furkan Almas, Melike Aybala Guzel, Berna Dogan, Damla Uludag, Nihal Karakas, Serdar Durdagi, Mustafa Guzel
Glioblastoma Multiforme (GBM) is the most aggressive brain tumor and classified as one of the deadliest cancers. The current treatment plans for GBM remains to be ineffective because of its rapid progress and inability of the drugs used to cross the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f4e8f713887971e8f5a0a382e20fdc
https://hdl.handle.net/20.500.12511/9120
https://hdl.handle.net/20.500.12511/9120
Autor:
BİLGESU ONUR SUCU, ELİF BEYZA KOÇ
Caffeic acid (CA), ferulic acid (FA) and caffeic acid phenethyl ester (CAPE) have a broad anticancer effect on various cell lines. In this study, nine ferulic and caffeic acid-based 1,2,4 and 1,3,4 oxadiazole molecular hybrids were synthesized and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664680878cca20723f27104edb3c75ef
https://hdl.handle.net/20.500.12511/9756
https://hdl.handle.net/20.500.12511/9756
Autor:
Damla, Uludağ, Sadık, Bay, Bilgesu Onur, Sucu, Özgecan, Şavluğ İpek, Thomas, Mohr, Mustafa, Güzel, Nihal, Karakaş
Publikováno v:
Frontiers in pharmacology. 13
Change in the energy metabolism of cancer cells, which display significant differences compared to normal cells, is a rising phenomenon in developing new therapeutic approaches against cancers. One of the metabolic enzymes, hexokinase-II (HK-II) is i
Publikováno v:
Molecules
Volume 24
Issue 24
Volume 24
Issue 24
Leishmaniasis is a neglected parasitic disease that is widely seen in more than 60 countries worldwide, including Turkey and its subcontinental region. There are several chemotherapy agents for the treatment of leishmaniasis, including pentavalent an
Autor:
Bilgesu Onur Sucu, Sukran Ozdatli Kurtulus, Busra Emine Yazici, Nihal Karakaş, Ozgecan Savlug Ipek, Mustafa Guzel
Warburg hypothesized that the energy consumption of cancer cells is different than the normal cells. When compared to normal conditions, cancer cells do not undergo tricarboxylic acid (TCA) cycle therefore resulting in more lactate in the cells. Glyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08103ef2f855afddb38cd041912d5087
https://hdl.handle.net/20.500.12511/4682
https://hdl.handle.net/20.500.12511/4682