Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bilge Birsoy"'
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52138 (2012)
Complex animals display bilaterally asymmetric motor behavior, or "motor handedness," often revealed by preferential use of limbs on one side. For example, use of right limbs is dominant in a strong majority of humans. While the mechanisms that estab
Externí odkaz:
https://doaj.org/article/7e9faa74ba8f4054abf369c998fb9f37
Autor:
Bilge Birsoy, Eric S Terry, Carl D. Meinhart, Pradeep M. Joshi, Marin Sigurdson, Joel H. Rothman, David Bothman
Despite a constant barrage of intrinsic and environmental noise, embryogenesis is remarkably reliable, suggesting the existence of systems that ensure faithful execution of this complex process. We report that earlyC. elegansembryos, which normally s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a363c4283b78505e42028e177e629d27
https://doi.org/10.1101/2020.06.02.128694
https://doi.org/10.1101/2020.06.02.128694
Publikováno v:
genesis. 52:581-587
Anatomical left-right (L/R) asymmetry in C. elegans is established in the four-cell embryo as a result of anteroposterior skewing of transverse mitotic spindles with a defined handedness. This event creates a chiral embryo and ultimately an adult bod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e100f6822439153855287b95a228a06a
https://doi.org/10.1002/dvg.22762
https://doi.org/10.1002/dvg.22762
Autor:
Pradeep M. Joshi, Yamila N. Torres Cleuren, Anna W. Santure, Joel H. Rothman, Melissa R. Alcorn, Davon C. Callander, Bilge Birsoy, Agustín López-Santos
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences
Although the arrangement of internal organs in most metazoans is profoundly left–right (L/R) asymmetric with a predominant handedness, rare individuals show full (mirror-symmetric) or partial (heterotaxy) reversals. While the nematodeCaenorhabditis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01cd7398bea2be7f709ba31e04e380d
https://pubmed.ncbi.nlm.nih.gov/27821534
https://pubmed.ncbi.nlm.nih.gov/27821534
Publikováno v:
Development. 134:503-513
Current models of canonical Wnt signaling assume that a pathway is active if β-catenin becomes nuclearly localized and Wnt target genes are transcribed. We show that, in Xenopus, maternal LRP6 is essential in such a pathway, playing a pivotal role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04abd7f727ef5bdf407ebcafa56e116a
https://doi.org/10.1242/dev.02739
https://doi.org/10.1242/dev.02739
Publikováno v:
Development. 133:15-20
Xenopus Vg1, a transforming growth factor β (Tgfβ)family member, was one of the first maternally localized mRNAs identified in vertebrates. Its restriction to the vegetal pole of the egg made it the ideal candidate to be the mesoderm-inducing signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f3160b0dedc7ba0fc13799f3f81ffd
https://doi.org/10.1242/dev.02144
https://doi.org/10.1242/dev.02144
Autor:
Chika Yokota, Helbert Puck, Dong Yan, Makoto Asashima, Xinhua Lin, Janet Heasman, Bilge Birsoy, Christopher Wylie, Qinghua Tao, Matt Kofron
Publikováno v:
Cell. 120:857-871
SummaryWnt signaling pathways play essential roles in patterning and proliferation of embryonic and adult tissues. In many organisms, this signaling pathway directs axis formation. Although the importance of intracellular components of the pathway, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876be77d4b7a0ba8735e5ad685641e0b
https://doi.org/10.1016/j.cell.2005.01.013
https://doi.org/10.1016/j.cell.2005.01.013
Publikováno v:
Genesis (New York, N.Y. : 2000). 52(6)
Anatomical left-right (L/R) handedness asymmetry in C. elegans is established in the four-cell embryo as a result of anteroposterior skewing of transverse mitotic spindles with a defined handedness. This event creates a chiral embryo and ultimately a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::370eb6770cd7e2c8228d332750795353
https://pubmed.ncbi.nlm.nih.gov/24585712
https://pubmed.ncbi.nlm.nih.gov/24585712
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e52138 (2012)
PLoS ONE, Vol 7, Iss 12, p e52138 (2012)
Complex animals display bilaterally asymmetric motor behavior, or "motor handedness," often revealed by preferential use of limbs on one side. For example, use of right limbs is dominant in a strong majority of humans. While the mechanisms that estab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f1193122f0b1c6ffcbcd3eb0b305a1
https://pubmed.ncbi.nlm.nih.gov/23300601
https://pubmed.ncbi.nlm.nih.gov/23300601
Autor:
Gonenc Ciliv, Berna B Kıvırcık Akdede, Halil Resmi, Zeliha Tunca, Basak Celtikci, Burak Baykara, Ayşegül Özerdem, Köksal Alptekin, Gül Ergör, Bilge Birsoy, H. Asuman Özkara
Dystonic movements and Parkinsonism are frequently seen in gangliosidoses and these conditions have been reported to modify dopaminergic plasticity. We investigated whether the activity of hexosaminidase, a type-two ganglioside (GM2) degrading enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035572664ffbf4f3e94364ca368ecb59
https://avesis.deu.edu.tr/publication/details/c7232d50-babc-4e65-8d50-400890adf967/oai
https://avesis.deu.edu.tr/publication/details/c7232d50-babc-4e65-8d50-400890adf967/oai