Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bilal R Malik"'
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62445 (2013)
In humans KCNQ2/3 heteromeric channels form an M-current that acts as a brake on neuronal excitability, with mutations causing a form of epilepsy. The M-current has been shown to be a key regulator of neuronal plasticity underlying associative memory
Externí odkaz:
https://doaj.org/article/1442a60120534175981982cfe0f069ed
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-21 (2019)
Abstract Due to their post-mitotic state, metabolic demands and often large polarised morphology, the function and survival of neurons is dependent on an efficient cellular waste clearance system both for generation of materials for metabolic process
Externí odkaz:
https://doaj.org/article/b757efe2e6bd443792bb3df08849d94b
Autor:
James P. Higham, Bilal R. Malik, Edgar Buhl, Jennifer M. Dawson, Anna S. Ogier, Katie Lunnon, James J. L. Hodge
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Alzheimer’s disease (AD) is the most common form of dementia and is characterized by intracellular neurofibrillary tangles of hyperphosphorylated Tau, including the 0N4R isoform and accumulation of extracellular amyloid beta (Aβ) plaques. However,
Externí odkaz:
https://doaj.org/article/dfb00dbe3c7f4fae983b05d1a792dda8
Autor:
Terrence M Trinca, Bilal R Malik
Exposure to various genotoxic and oxidative stresses can induce changes in the internal state of a cell leading to cell death. Ionizing radiation is routinely used in clinics to treat various types of cancers, with secondary effects sometimes damagin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ec6640ad36daeb4b55f2402dcffa751
https://doi.org/10.21203/rs.3.rs-1283711/v1
https://doi.org/10.21203/rs.3.rs-1283711/v1
Publikováno v:
Molecular Brain
Molecular Brain, Vol 12, Iss 1, Pp 1-21 (2019)
Molecular Brain, Vol 12, Iss 1, Pp 1-21 (2019)
Due to their post-mitotic state, metabolic demands and often large polarised morphology, the function and survival of neurons is dependent on an efficient cellular waste clearance system both for generation of materials for metabolic processes and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293c4c168d177e621eee593997d5c26f
https://doi.org/10.1186/s13041-019-0504-x
https://doi.org/10.1186/s13041-019-0504-x
Publikováno v:
Human Molecular Genetics
Mutations in VPS35 (PARK17) cause autosomal dominant, late onset Parkinson's disease (PD). VPS35 forms a core component of the retromer complex that mediates the retrieval of membrane proteins from endosomes back to either the Golgi or plasma membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2cf8e79e24bcade205163d9851cc97cb
https://pubmed.ncbi.nlm.nih.gov/26251041
https://pubmed.ncbi.nlm.nih.gov/26251041
Autor:
James J.L. Hodge, Bilal R. Malik
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28e82961dad41c32139f576143a69b2d
https://doi.org/10.3791/50107-v
https://doi.org/10.3791/50107-v