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Synthesis and potential antimicrobial activity of novel α-aminophosphonates derivatives bearing substituted quinoline or quinolone and thiazole moieties

Autor: Bilal Litim, Saida Meliani, Abbes Boukhari, Abdelghani Djahoudi

Publikováno v: Medicinal Chemistry Research

To develop novel antimicrobial agents, and based on the biologically active heterocyclic quinoline and thiazole substituted, a series of novel α-aminophosphonates (9a–h) and (10i–l) derivatives that incorporated quinoline or quinolone, and couma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613c1eaf02cbf521d867a02c9fcdf3f7
https://doi.org/10.1007/s00044-021-02815-5

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Synthesis and potent antimicrobial activity of novel coumarylthiazole α-aminophosphonates derivatives

Autor: Zinelaabidine Cheraiet, Saida Meliani, Abdelghani Djahoudi, Abbes Boukhari, Bilal Litim

Publikováno v: Molecular diversity. 26(2)

Herein, we reported a novel series of α-aminophosphonates derivatives (IV)a–m bearing an important pharmacophore coumarylthiazole moiety. All the new compounds have been synthesized via Kabachnik–Fields reaction under ultrasonic irradiation. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882f1b47d8d030bd6740de1ba4afab26
https://pubmed.ncbi.nlm.nih.gov/34117993

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