Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Bilal Cakir"'
Autor:
Mehmet H. Kural, Umidahan Djakbarova, Bilal Cakir, Yoshiaki Tanaka, Emily T. Chan, Valeria I. Arteaga Muniz, Yasaman Madraki, Hong Qian, Jinkyu Park, Lorenzo R. Sewanan, In-Hyun Park, Laura E. Niklason, Comert Kural
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-11 (2024)
Abstract The transmembrane death receptor Fas transduces apoptotic signals upon binding its ligand, FasL. Although Fas is highly expressed in cancer cells, insufficient cell surface Fas expression desensitizes cancer cells to Fas-induced apoptosis. H
Externí odkaz:
https://doaj.org/article/544a7a26c62646bdaf6e0dc321de4417
Autor:
Bilal Cakir, Yoshiaki Tanaka, Ferdi Ridvan Kiral, Yangfei Xiang, Onur Dagliyan, Juan Wang, Maria Lee, Allison M. Greaney, Woo Sub Yang, Catherine duBoulay, Mehmet Hamdi Kural, Benjamin Patterson, Mei Zhong, Jonghun Kim, Yalai Bai, Wang Min, Laura E. Niklason, Prabir Patra, In-Hyun Park
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The study of human microglia function in health and disease is limited by the availability of sound models. Here, the authors develop a method to generate functional microglia in human cortical organoids and investigate the role of human microglia du
Externí odkaz:
https://doaj.org/article/f7e442e71a714aed94079c5c43728648
Dyslexia associated gene KIAA0319 regulates cell cycle during human neuroepithelial cell development
Autor:
Steven Paniagua, Bilal Cakir, Yue Hu, Ferdi Ridvan Kiral, Yoshiaki Tanaka, Yangfei Xiang, Benjamin Patterson, Jeffrey R. Gruen, In-Hyun Park
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Dyslexia, also known as reading disability, is defined as difficulty processing written language in individuals with normal intellectual capacity and educational opportunity. The prevalence of dyslexia is between 5 and 17%, and the heritability range
Externí odkaz:
https://doaj.org/article/a2589f321b944831a25bd115505eeb24
Autor:
Bilal Cakir, In-Hyun Park
Publikováno v:
eLife, Vol 11 (2022)
Fusing brain organoids with blood vessel organoids leads to the incorporation of non-neural endothelial cells and microglia into the brain organoids.
Externí odkaz:
https://doaj.org/article/0b5ca0d445b340d18d767ce28b5ff597
Publikováno v:
STAR Protocols, Vol 1, Iss 1, Pp 100001- (2020)
Summary: Thalamus is a critical information relay hub in the cortex; its malfunction causes multiple neurological and psychiatric disorders. However, there are no model systems to study the development and function of human thalamus. Here, we present
Externí odkaz:
https://doaj.org/article/e6939e733f994f98bf024dcf5ecfff43
Publikováno v:
Cell Reports, Vol 30, Iss 6, Pp 1682-1689.e3 (2020)
Summary: Human brain organoid systems offer unprecedented opportunities to investigate both neurodevelopmental and neurological disease. Single-cell-based transcriptomics or epigenomics have dissected the cellular and molecular heterogeneity in the b
Externí odkaz:
https://doaj.org/article/5503410fcf7c4ee49349961dce7adcaf
Autor:
Kun-Yong Kim, Yoshiaki Tanaka, Juan Su, Bilal Cakir, Yangfei Xiang, Benjamin Patterson, Junjun Ding, Yong-Wook Jung, Ji-Hyun Kim, Eriona Hysolli, Haelim Lee, Rana Dajani, Jonghwan Kim, Mei Zhong, Jeong-Heon Lee, David Skalnik, Jeong Mook Lim, Gareth J. Sullivan, Jianlong Wang, In-Hyun Park
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Uhrf1 is a known regulator of heterochromatin and DNA methylation in embryonic stem cells (ESCs). Here, the authors demonstrate that Uhrf1 acts together with the Set1/COMPASS complex regulator of active transcription to promote H3K4 methylation at bi
Externí odkaz:
https://doaj.org/article/de5d0fb025b047ba960f4909f2822905
Autor:
Quynh Hoang Le, Bahareh Farasati Far, S. Mohammad Sajadi, Bahar Saadaie Jahromi, Sogand Kaspour, Bilal Cakir, Zahra Abdelmalek, Mustafa Inc
Publikováno v:
Engineering Analysis with Boundary Elements. 150:583-598
Publikováno v:
Neuron. 110(21)
In the central nervous system (CNS), microglia carry out multiple tasks related to brain development, maintenance of brain homeostasis, and function of the CNS. Recent advanced in vitro model systems allow us to perform more detailed and specific ana
Bioactive peptides from milk proteins are dietary components with various biological properties and therapeutic effects in a variety of health conditions, including cancer. In this study, the effects of goat milk proteins and bioactive peptides on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c3794e3b907c368846c1943afe9381
https://hdl.handle.net/11424/291318
https://hdl.handle.net/11424/291318