Výsledky vyhledávání - "Bilal AbuAsal"

Akademický článek

Digital technologies: Innovations that transform the face of drug development

Autor: Elena S. Izmailova, Bilal AbuAsal, Hazem E. Hassan, Anindita Saha, Diane Stephenson

Publikováno v: Clinical and Translational Science, Vol 16, Iss 8, Pp 1323-1330 (2023)

Abstract Recently, digital health technologies (DHTs) and digital biomarkers have gained a lot of traction in clinical investigations, motivating sponsors, investigators, and regulators to discuss and implement integrated approaches for deploying DHT

Externí odkaz: https://doaj.org/article/4a9c80ec00eb4785847df54be7b4d3dd

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Achieving big with small: quantitative clinical pharmacology tools for drug development in pediatric rare diseases

Autor: Mariam A. Ahmed, Janelle Burnham, Gaurav Dwivedi, Bilal AbuAsal

Publikováno v: Journal of Pharmacokinetics and Pharmacodynamics.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85c4c09c3c62d20a034e8a45df4201a2
https://doi.org/10.1007/s10928-023-09863-x

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Abstract 4629: Physiologically based pharmacokinetic model and correlative in vitro assessment of metabolism-based interaction between Everolimus and PI3K/mTOR inhibitor BEZ235

Autor: Larry Sallans, John C. Morris, Ganesh Moorthy, George Thomas, Bilal Abuasal, Pankaj B. Desai

Publikováno v: Cancer Research. 74:4629-4629

The PI3/Akt/mTOR kinase is a key intracellular signaling pathway and deregulation of this signaling pathway has been implicated in tumorigenesis and in numerous malignancies. Everolimus (RAD) is a potent allosteric inhibitor of mTORC1 and BEZ235 is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b74b6c2e846289b52b1727ceec7106c3
https://doi.org/10.1158/1538-7445.am2014-4629

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