Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Bijun Wen"'
Autor:
Bijun Wen, Amber Farooqui, Celine Bourdon, Nawar Tarafdar, Moses Ngari, Emmanuel Chimwezi, Johnstone Thitiri, Laura Mwalekwa, Judd L. Walson, Wieger Voskuijl, James A. Berkley, Robert H. J. Bandsma
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-10 (2023)
Abstract Background Children admitted to hospital with complicated severe malnutrition (CSM) have high mortality despite compliance with standard WHO management guidelines. Limited data suggests a relationship between intestinal dysfunction and poor
Externí odkaz:
https://doaj.org/article/ee4ec22ff3ee4d6aafaa72fdad5a8e33
Autor:
Alex M Cressman, Bijun Wen, Sudipta Saha, Hae Young Jun, Riley Waters, Sharan Lail, Aneela Jabeen, Radha Koppula, Lauren Lapointe-Shaw, Kathleen A Sheehan, Adina Weinerman, Nick Daneman, Amol A Verma, Fahad Razak, Derek MacFadden
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0299473 (2024)
ObjectiveCurrent scores for predicting sepsis outcomes are limited by generalizability, complexity, and electronic medical record (EMR) integration. Here, we validate a simple EMR-based score for sepsis outcomes in a large multi-centre cohort.DesignA
Externí odkaz:
https://doaj.org/article/0cd88caec3b44047a5cee6969064cabe
Autor:
Bijun Wen, Daniella Brals, Celine Bourdon, Lauren Erdman, Moses Ngari, Emmanuel Chimwezi, Isabel Potani, Johnstone Thitiri, Laura Mwalekwa, James A. Berkley, Robert H. J. Bandsma, Wieger Voskuijl
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Despite adherence to WHO guidelines, inpatient mortality among sick children admitted to hospital with complicated severe acute malnutrition (SAM) remains unacceptably high. Several studies have examined risk factors present at ad
Externí odkaz:
https://doaj.org/article/c41e69b8363c44278e2543630e185e0c
Autor:
Gerard Bryan Gonzales, James M. Njunge, Bonface M Gichuki, Bijun Wen, Moses Ngari, Isabel Potani, Johnstone Thitiri, Debby Laukens, Wieger Voskuijl, Robert Bandsma, Jill Vanmassenhove, James A Berkley
Publikováno v:
EBioMedicine, Vol 79, Iss , Pp 103991- (2022)
Summary: Background: While fluid flows in a steady state from plasma, through interstitium, and into the lymph compartment, altered fluid distribution and oedema can result from abnormal Starling's forces, increased endothelial permeability or impair
Externí odkaz:
https://doaj.org/article/9e9ea7a2a95346d3bf771d6f9f937ab9
Autor:
Gerard Bryan Gonzales, James M. Njunge, Bonface M. Gichuki, Bijun Wen, Isabel Potani, Wieger Voskuijl, Robert H. J. Bandsma, James A. Berkley
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract HIV infection affects up to 30% of children presenting with severe acute malnutrition (SAM) in Africa and is associated with increased mortality. Children with SAM are treated similarly regardless of HIV status, although mechanisms of nutrit
Externí odkaz:
https://doaj.org/article/30b70b931331474cb60178c3f2da80ff
Publikováno v:
Microorganisms, Vol 7, Iss 2, p 51 (2019)
In vitro and in vivo studies suggest that selected Bifidobacterium bifidum strains sustain intestinal homeostasis. This study aimed to examine whether the administration of B. bifidum MIMBb75 (BB75) attenuates Citrobacter rodentium infection, a murin
Externí odkaz:
https://doaj.org/article/f2f7dab3a44c48acad605ddfcdbb4208
Autor:
Christopher R. Villa, Jianmin Chen, Bijun Wen, Sandra M. Sacco, Amel Taibi, Wendy E. Ward, Elena M. Comelli
Publikováno v:
Nutrients, Vol 8, Iss 11, p 675 (2016)
Obesity is associated with systemic inflammation and impaired bone health. Vitamin D regulates bone metabolism, and has anti-inflammatory properties and epigenetic effects. We showed that exposure to high dietary vitamin D during pregnancy and lactat
Externí odkaz:
https://doaj.org/article/4e550205c2bf42aeb44ceed38b0a492f
Autor:
Lijun Chi, Dorothy Lee, Sharon Leung, Guanlan Hu, Bijun Wen, Paul Delgado-Olguin, Miluska Vissa, Ren Li, John Brumell, Peter Kim, Robert H J Bandsma
Peroxisomes are essential for mitochondrial health. However, the mechanisms underlying the relationship between these two organelles in hepatic metabolism remains unclear. To address this, we developed a conditional hepatocyte specific Pex16 deficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23d315483d36b51ad3e29ca2285f9aa8
https://doi.org/10.21203/rs.3.rs-2496824/v1
https://doi.org/10.21203/rs.3.rs-2496824/v1
Autor:
Wieger Voskuijl, Johnstone Thitiri, Daniella Brals, Bijun Wen, Lauren Erdman, Robert H. J. Bandsma, James A. Berkley, Laura Mwalekwa, Isabel Potani, Emmanuel Chimwezi, Moses Ngari, Celine Bourdon
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
BMC Medicine
BMC medicine, 19(1):222. BioMed Central
BMC Medicine
BMC medicine, 19(1):222. BioMed Central
Background Despite adherence to WHO guidelines, inpatient mortality among sick children admitted to hospital with complicated severe acute malnutrition (SAM) remains unacceptably high. Several studies have examined risk factors present at admission f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4774bb6b6f582e444a80ce90fb30250a
https://doaj.org/article/c41e69b8363c44278e2543630e185e0c
https://doaj.org/article/c41e69b8363c44278e2543630e185e0c
Autor:
Bijun Wen, James M. Njunge, Celine Bourdon, Gerard Bryan Gonzales, Bonface M. Gichuki, Dorothy Lee, David S. Wishart, Moses Ngari, Emmanuel Chimwezi, Johnstone Thitiri, Laura Mwalekwa, Wieger Voskuijl, James A. Berkley, Robert HJ Bandsma
Publikováno v:
Science Advances, 8(7)
Science Advances 8 (2022) 7
Science Advances, 8(7):eabj6779. American Association for the Advancement of Science
Wen, B, Njunge, J M, Bourdon, C, Gonzales, G B, Gichuki, B M, Lee, D, Wishart, D S, Ngari, M, Chimwezi, E, Thitiri, J, Mwalekwa, L, Voskuijl, W, Berkley, J A & Bandsma, R H J 2022, ' Systemic inflammation and metabolic disturbances underlie inpatient mortality among ill children with severe malnutrition ', Science Advances, vol. 8, no. 7, eabj6779 . https://doi.org/10.1126/sciadv.abj6779
Science advances, 8(7):eabj6779. American Association for the Advancement of Science
Science Advances 8 (2022) 7
Science Advances, 8(7):eabj6779. American Association for the Advancement of Science
Wen, B, Njunge, J M, Bourdon, C, Gonzales, G B, Gichuki, B M, Lee, D, Wishart, D S, Ngari, M, Chimwezi, E, Thitiri, J, Mwalekwa, L, Voskuijl, W, Berkley, J A & Bandsma, R H J 2022, ' Systemic inflammation and metabolic disturbances underlie inpatient mortality among ill children with severe malnutrition ', Science Advances, vol. 8, no. 7, eabj6779 . https://doi.org/10.1126/sciadv.abj6779
Science advances, 8(7):eabj6779. American Association for the Advancement of Science
Children admitted to hospital with an acute illness and concurrent severe malnutrition [complicated severe malnutrition (CSM)] have a high risk of dying. The biological processes underlying their mortality are poorly understood. In this case-control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c012dd4507f213cd4081a2160ab498
https://research.wur.nl/en/publications/systemic-inflammation-and-metabolic-disturbances-underlie-inpatie
https://research.wur.nl/en/publications/systemic-inflammation-and-metabolic-disturbances-underlie-inpatie