Inhibition of NRF2 signaling overcomes acquired resistance to arsenic trioxide in FLT3-mutated Acute Myeloid Leukemia.

Autor: Jebanesan DZP; Department of Hematology, Christian Medical College Vellore-Ranipet Campus, Tamil Nadu, Vellore, 632517, India.; Manipal Academy of Higher Education, Manipal, India., Illangeswaran RSS; Department of Hematology, Christian Medical College Vellore-Ranipet Campus, Tamil Nadu, Vellore, 632517, India., Rajamani BM; Department of Hematology, Christian Medical College Vellore-Ranipet Campus, Tamil Nadu, Vellore, 632517, India., Vidhyadharan RT; Department of Hematology, Christian Medical College Vellore-Ranipet Campus, Tamil Nadu, Vellore, 632517, India., Das S; Department of Hematology, Christian Medical College Vellore-Ranipet Campus, Tamil Nadu, Vellore, 632517, India., Bijukumar NK; Department of Hematology, Christian Medical College Vellore-Ranipet Campus, Tamil Nadu, Vellore, 632517, India., Balakrishnan B; Department of Hematology, Christian Medical College Vellore-Ranipet Campus, Tamil Nadu, Vellore, 632517, India.; Department of Integrative Biology, School of BioSciences and Technology, Vellore Institute of Technology, Vellore, India., Mathews V; Department of Hematology, Christian Medical College Vellore-Ranipet Campus, Tamil Nadu, Vellore, 632517, India., Velayudhan SR; Department of Hematology, Christian Medical College Vellore-Ranipet Campus, Tamil Nadu, Vellore, 632517, India.; Adjunct Scientist, Centre for Stem Cell Research, A Unit of InStem Bengaluru, CMC Campus, Vellore, India., Balasubramanian P; Department of Hematology, Christian Medical College Vellore-Ranipet Campus, Tamil Nadu, Vellore, 632517, India. bpoonkuzhali@cmcvellore.ac.in.

Publikováno v: Annals of hematology [Ann Hematol] 2024 Jun; Vol. 103 (6), pp. 1919-1929. Date of Electronic Publication: 2024 Apr 17.