Zobrazeno 1 - 10
of 10 422
pro vyhledávání: '"Bijlsma, A."'
To improve the quality of programs we provide an approach to guidance in the process of program development. At the higher level the various activities and their dependencies to structure the process are identified. At the lower level, detailed, prac
Externí odkaz:
http://arxiv.org/abs/2411.13200
Autor:
Brinksma, Wouter, Wernsen, William, Verduin, Evert, Hilberink, Herman, de Beer, Patrick, Bijlsma, Lex, Passier, Harrie
This report investigates the relationship between software refactoring and behavior preservation. Existing behavior preservation analyses often lack comprehensive insights into refactoring rejections and do not provide actionable solutions. To addres
Externí odkaz:
http://arxiv.org/abs/2411.08648
Publikováno v:
Oncogenesis, Vol 13, Iss 1, Pp 1-14 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC) presents significant challenges due to the inadequacy of existing chemotherapeutics, which often result in toxicity-dependent dose limitations and premature cessation of therapy. Targeted delivery of t
Externí odkaz:
https://doaj.org/article/21affa4ad5fa4ab093c47cbbe4cb4702
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 4947-4958 (2024)
Xuechun Li,1 Dennis Steenhuis,1 Maarten J Bijlsma,1,2 Stijn de Vos,1 Sumaira Mubarik,1 Jens HJ Bos,1 Catharina CM Schuiling-Veninga,1 Eelko Hak1 1Pharmacotherapy, Epidemiology and Economics, Groningen Research Institute of Pharmacy, University of Gro
Externí odkaz:
https://doaj.org/article/4ab4e93d498d471bb027ac497f0412b6
The quality of software produced by students is often poor. How to teach students to develop good quality software has long been a topic in computer science education and research. We must conclude that we still do not have a good answer to this ques
Externí odkaz:
http://arxiv.org/abs/2309.02221
Autor:
Andrea Vallés‐Martí, Richard R. deGoeij‐de Haas, Alex A. Henneman, Sander R. Piersma, Thang V. Pham, Jaco C. Knol, Joanne Verheij, Frederike Dijk, Hans Halfwerk, Elisa Giovannetti, Connie R. Jiménez, Maarten F. Bijlsma
Publikováno v:
Molecular Oncology, Vol 18, Iss 8, Pp 2020-2041 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with a limited number of known driver mutations but considerable cancer cell heterogeneity. Phosphoproteomics provides a direct read‐out of aberrant signaling and the resultant clinic
Externí odkaz:
https://doaj.org/article/e8ff82023c7546bf9b7c1d4e26f666f5
Autor:
Charlotte I. Stroes, Sybren L. Meijer, Geert-Jan Creemers, Gerrit K.J. Hooijer, Nadia Haj Mohammad, Maartje Los, Marije Slingerland, Geke A.P. Hospers, Annemieke Cats, Laurens V. Beerepoot, Maarten F. Bijlsma, Hanneke W.M. van Laarhoven
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102079- (2024)
Background: HER2 targeting in esophageal adenocarcinoma (EAC) has shown potential, but often fails to show durable response. Given the contributions of the tumor immune microenvironment (TIME) to therapeutic responses, we aimed to chart the TIME char
Externí odkaz:
https://doaj.org/article/140bcec5bc5649c49d43672c34967d9a
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
The most common source of Radiofrequency Electromagnetic Field (RF-EMF) exposures during sleep includes digital devices, yet there are no studies investigating the impact of multi-night exposure to electromagnetic fields emitted from a baby monitor o
Externí odkaz:
https://doaj.org/article/f03bc317d5d8465786ee5f973d7e8edc
Publikováno v:
Informatics in Education, Vol 23, Iss 2, Pp 361-383 (2024)
This paper presents the first experiences of the use of an online open-source repository with programming exercises. The repository is independent of any specific teaching approach. Students can search for and select an exercise that trains the progr
Externí odkaz:
https://doaj.org/article/01b88784f2864753b491e003414827f4
Autor:
Joana Gonçalves, Joana D. Amaral, Rita Capela, Maria de Jesus Perry, Cláudia Braga, Maria Manuela Gaspar, Fátima M. Piedade, Lubertus Bijlsma, Antoni Roig, Sandra N. Pinto, Rui Moreira, Pedro Florindo, Cecília M. P. Rodrigues
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Inducing necroptosis in cancer cells has emerged as an effective strategy to overcome drug resistance. However, while organic small molecules have been extensively studied for this purpose, metal-based compounds have received relatively litt
Externí odkaz:
https://doaj.org/article/cfb9a99efa384c4998ddab96fc03402d