Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Bijan Rafii"'
Autor:
Chris Davreux, Jinwen Ding, Andrew John Dickie, Alan Keith Tanswell, Hugh O'Brodovich, Bijan Rafii, John Piovesan, Ori D. Rotstein
Publikováno v:
Pediatric Research. 48:304-310
The acute respiratory distress syndrome is characterized by impairment of the alveolar-capillary barrier. Our laboratory has shown that distal lung epithelial cell (DLEC) amiloride-sensitive Na+ transport is impaired by in vitro coculture with endoto
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 20:1028-1040
The rat amiloride-sensitive epithelial sodium channel (rENaC) is the rate-limiting step for vectorial transport of Na+ across tight epithelia. The complex is composed of three subunits, alpha, beta, and gamma. Expression of the subunits has been show
Autor:
Bryan Baranowski, Bijan Rafii, Anthony K.C. Chan, Hugh O'Brodovich, Martin Post, Paul Monagle, Mingyao Liu, Leslie R. Berry, Maureen Andrew
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 19:419-425
Respiratory distress syndrome (RDS) is characterized by intrapulmonary fibrin deposition, which can adversely affect surfactant function, and stimulate fibroblast proliferation, which may contribute to the development of bronchopulmonary dysplasia (B
Autor:
John Dickie, David J. Hackam, Yoshinori Marunaka, Ori D. Rotstein, Bijan Rafii, Yutaka Shintani, Hugh O'Brodovich, Jin Wen Ding
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 274:L378-L387
Distal lung epithelial cells (DLECs) play an active role in fluid clearance from the alveolus by virtue of their ability to actively transport Na+from the alveolus to the interstitial space. The present study evaluated the ability of activated macrop
Publikováno v:
American Journal of Physiology-Cell Physiology. 264:C1532-C1537
The antibiotic novobiocin has been previously reported to increase Na+ transport in frog skin, presumably by attenuation of Na+ self-inhibition of Na+ channels. To determine whether novobiocin had similar effects and utilized a similar mechanism in m
Autor:
Bijan Rafii, Hugh O'Brodovich
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 71:54-57
To determine whether basolateral K channels play an important role in the basal and β-agonist stimulated ion transport by fetal distal lung epithelium we harvested these cells from fetal rats (20 days gestation, term = 22 days) and studied them in U
Autor:
Wolfram Ruf, Frank Niessen, Eric Vachon, Wolfgang F. Vogel, Gregory P. Downey, Theo J. Moraes, Tomoko Suzuki, Bijan Rafii, Hugh O'Brodovich, Raiza Martin
Publikováno v:
Experimental lung research. 35(2)
Proteinases contribute to the pathogenesis of various lung diseases, partly through activating cell surface receptors by limited proteolytic cleavage. The authors provide evidence that in primary cultures of distal lung epithelia, basolateral proteas
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 5:377-384
Normal clearance of alveolar liquid following birth requires active Na transport; however, the contribution of Na channels, Na-H antiports, and Na-glucose symports is unknown. We demonstrated that intraalveolar instillation of amiloride (n = 6) or th
Publikováno v:
Neonatology. 59:61-68
The active transport of ions across fetal pulmonary epithelium results in lung fluid secretion. This study investigated the potential difference (PD) across fetal type II alveolar epithelium, one of the several epithelial cell types in the fetal lung
Autor:
Gail Otulakowski, Ernest Cutz, Bijan Rafii, Hugh O'Brodovich, Muhammad Shahidur Rahman, Nael Elias
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 293(3)
Edema fluid (EF) increases epithelial Na+ transport by rat fetal distal lung epithelia (FDLE) and induces net lung fluid absorption in fetal mouse lung explants [Rafii B, Gillie DJ, Sulowski C, Hannam V, Cheung T, Otulakowski G, Barker PM, O'Brodovic