Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Bih-Rong Wei"'
Autor:
Sarah M. Hammoudeh, Yeap Ng, Bih-Rong Wei, Thomas D. Madsen, Mukesh P. Yadav, R. Mark Simpson, Roberto Weigert, Paul A. Randazzo
Publikováno v:
Cell Reports: Methods, Vol 4, Iss 7, Pp 100802- (2024)
Summary: PAX3/7 fusion-negative rhabdomyosarcoma (FN-RMS) is a childhood mesodermal lineage malignancy with a poor prognosis for metastatic or relapsed cases. Limited understanding of advanced FN-RMS is partially attributed to the absence of sequenti
Externí odkaz:
https://doaj.org/article/de21190a5a7242a48483a45be5f5303c
Autor:
Bih-Rong Wei, Cody J. Peer, William J. Richardson, Stephen M. Hewitt, William D. Figg, R. Mark Simpson
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Activation of one or both the Ras/MAPK and PI3K/Akt/mTOR signal transduction pathways are known to mediate oncogenicity of several canine and human cancers, including mucosal melanomas. Reciprocal cross activation between the two pathways can be a so
Externí odkaz:
https://doaj.org/article/b3aa62de85994eb88e051c19e87a5dbd
Autor:
Bih-Rong Wei PhD, Charles H. Halsey DVM, PhD, Shelley B. Hoover BS, Munish Puri PhD, Howard H. Yang PhD, Brandon D. Gallas PhD, Maxwell P. Lee PhD, Weijie Chen PhD, Amy C. Durham MS, VMD, Jennifer E. Dwyer MS, Melissa D. Sánchez VMD, PhD, Ryan P. Traslavina DVM, Chad Frank MS, DVM, Charles Bradley VMD, Lawrence D. McGill DVM, PhD, D. Glen Esplin DVM, PhD, Paula A. Schaffer DVM, MS, Sarah D. Cramer DVM, PhD, L. Tiffany Lyle DVM, PhD, Jessica Beck DVM, Elizabeth Buza DVM, Qi Gong MS, Stephen M. Hewitt MD, PhD, R. Mark Simpson DVM, PhD
Publikováno v:
Academic Pathology, Vol 6 (2019)
Validating digital pathology as substitute for conventional microscopy in diagnosis remains a priority to assure effectiveness. Intermodality concordance studies typically focus on achieving the same diagnosis by digital display of whole slide images
Externí odkaz:
https://doaj.org/article/5fda47df28cb483994b0c7c61cbbc949
Autor:
Munish Puri, Shelley B Hoover, Stephen M Hewitt, Bih-Rong Wei, Hibret Amare Adissu, Charles H C Halsey, Jessica Beck, Charles Bradley, Sarah D Cramer, Amy C Durham, D Glen Esplin, Chad Frank, L Tiffany Lyle, Lawrence D McGill, Melissa D Sánchez, Paula A Schaffer, Ryan P Traslavina, Elizabeth Buza, Howard H Yang, Maxwell P Lee, Jennifer E Dwyer, R Mark Simpson
Publikováno v:
Journal of Pathology Informatics, Vol 10, Iss 1, Pp 4-4 (2019)
Background: Determining mitotic index by counting mitotic figures (MFs) microscopically from tumor areas with most abundant MF (hotspots [HS]) produces a prognostically useful tumor grading biomarker. However, interobserver concordance identifying MF
Externí odkaz:
https://doaj.org/article/9a77d4908f454041951426815a0dd244
Autor:
Belen Hernandez, Hibret A. Adissu, Bih-Rong Wei, Helen T. Michael, Glenn Merlino, R. Mark Simpson
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 2, p 394 (2018)
Melanoma remains mostly an untreatable fatal disease despite advances in decoding cancer genomics and developing new therapeutic modalities. Progress in patient care would benefit from additional predictive models germane for human disease mechanisms
Externí odkaz:
https://doaj.org/article/86a496960dc242ddb0dea779a49a0a00
Autor:
Bih-Rong Wei, Shelley B Hoover, Mark M Ross, Weidong Zhou, Francesco Meani, Jennifer B Edwards, Elizabeth I Spehalski, John I Risinger, W Gregory Alvord, Octavio A Quiñones, Claudio Belluco, Luca Martella, Elio Campagnutta, Antonella Ravaggi, Ren-Ming Dai, Paul K Goldsmith, Kevin D Woolard, Sergio Pecorelli, Lance A Liotta, Emanuel F Petricoin, R Mark Simpson
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7670 (2009)
BACKGROUND:Ovarian cancer is the 5th leading cause of cancer related deaths in women. Five-year survival rates for early stage disease are greater than 94%, however most women are diagnosed in advanced stage with 5 year survival less than 28%. Improv
Externí odkaz:
https://doaj.org/article/d79f61c6375e48cfa09cb53a265f3c63
Autor:
Joshua D Webster, Aleksandra M Michalowski, Jennifer E Dwyer, Kara N Corps, Bih-Rong Wei, Tarja Juopperi, Shelley B Hoover, R Mark Simpson
Publikováno v:
Journal of Pathology Informatics, Vol 3, Iss 1, Pp 18-18 (2012)
The extent to which histopathology pattern recognition image analysis (PRIA) agrees with microscopic assessment has not been established. Thus, a commercial PRIA platform was evaluated in two applications using whole-slide images. Substantial agreeme
Externí odkaz:
https://doaj.org/article/efc9669faad84b2399bdf2c493877600
Autor:
R. Mark Simpson, William D. Figg, Tyler J. Peat, Maxwell Lee, Howard Yang, Priya Shankarappa, Hibret A. Adissu, Jennifer E. Dwyer, Cody J. Peer, Shelley B. Hoover, Bih-Rong Wei
Supplemental text file for materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee7b2dcfeddce5a3cf6688a74914529
https://doi.org/10.1158/1535-7163.22519032
https://doi.org/10.1158/1535-7163.22519032
Autor:
Michael M. Gottesman, Zhengping Zhuang, R. Mark Simpson, Matthew D. Hall, James P. Madigan, Bih-Rong Wei, Ki-Eun Chang
Despite early positive response to platinum-based chemotherapy, the majority of ovarian carcinomas develop resistance and progress to fatal disease. Protein phosphatase 2A (PP2A) is a ubiquitous phosphatase involved in the regulation of DNA-damage re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f39a0a1a785a07c5d5633ff146a95518
https://doi.org/10.1158/1535-7163.c.6536818.v1
https://doi.org/10.1158/1535-7163.c.6536818.v1
Autor:
Michael M. Gottesman, Zhengping Zhuang, R. Mark Simpson, Matthew D. Hall, James P. Madigan, Bih-Rong Wei, Ki-Eun Chang
Supplementary figures S1-S5. Supplementary Figure S1. Western blot showing differential expression of PP2A-C (catalytic subunit) and PP2A-A (scaffold subunit) in different ovarian cancer cell lines; Supplementary Figure S2. LB100 is not a substrate f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4212539ae7609edf09cb39b307ea9e
https://doi.org/10.1158/1535-7163.22501543
https://doi.org/10.1158/1535-7163.22501543