Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Bih-Hwa Shieh"'
Publikováno v:
Fly, Vol 15, Iss 1, Pp 8-27 (2021)
Unregulated Ca2+ influx affects intracellular Ca2+ homoeostasis, which may lead to neuronal death. In Drosophila, following the activation of rhodopsin the TRP Ca2+ channel is open to mediate the light-dependent depolarization. A constitutively activ
Externí odkaz:
https://doaj.org/article/8ccc208d52f84b3f9821e65d3c5c038e
Publikováno v:
Journal of Biological Chemistry. Jun2023, Vol. 299 Issue 6, p1-12. 12p.
Publikováno v:
Fly. 15:8-27
Unregulated Ca2+ influx affects intracellular Ca2+ homoeostasis, which may lead to neuronal death. In Drosophila, following the activation of rhodopsin the TRP Ca2+ channel is open to mediate the l...
Publikováno v:
eLS
Receptor adaptation mechanisms involve regulation of the number, sensitivity and subcellular localization of receptors that detect environmental cues and convert extracellular signals into a change of intracellular events. Keywords: regulation of rec
Publikováno v:
Fly (Austin)
Unregulated Ca(2+) influx affects intracellular Ca(2+) homoeostasis, which may lead to neuronal death. In Drosophila, following the activation of rhodopsin the TRP Ca(2+) channel is open to mediate the light-dependent depolarization. A constitutively
Publikováno v:
Journal of Neuroscience. 32:10758-10766
Arrestins belong to a family of multifunctional adaptor proteins that regulate internalization of diverse receptors including G-protein-coupled receptors (GPCRs). Defects associated with endocytosis of GPCRs have been linked to human diseases. We use
Publikováno v:
Journal of Biological Chemistry. 284:11100-11109
Ca2+ modulates the visual response in both vertebrates and invertebrates. In Drosophila photoreceptors, an increase of cytoplasmic Ca2+ mimics light adaptation. Little is known regarding the mechanism, however. We explored the role of the sole Drosop
Publikováno v:
Journal of Neurochemistry. 104:1526-1535
J. Neurochem. (2008) 104, 1526–1535. Abstract Drosophila transient-receptor-potential (TRP) is a Ca2+ channel responsible for the light-dependent depolarization of photoreceptors. TRP is anchored to a macromolecular complex by tethering to inactiva
Publikováno v:
The FASEB Journal. 29
Publikováno v:
The Journal of Neuroscience. 26:8570-8577
Drosophilavisual signaling is one of the fastest G-protein-coupled transduction cascades, because effector and modulatory proteins are organized into a macromolecular complex (“transducisome”). Assembly of the complex is orchestrated by inactivat