Structural basis for the membrane fusion step in Hantavirus entry

Autor: Shmuel, W, Bar-Rogovsky, H, Bignon, EA, Tischler, ND, Modis, Y, Dessau, M

Hantaviruses are important emerging human pathogens and are the causative agents of serious diseases in humans with high mortality rates. Like other members in the Bunyaviridae family their M segment encodes two glycoproteins, GN and GC, which are re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::591f65cc923121c5a6f73d43ff85fb6e

The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.

Autor: Serris A; Institut Pasteur, Structural Virology Unit, and CNRS UMR 3569, Paris, France., Stass R; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Bignon EA; Fundación Ciencia & Vida, Molecular Virology Laboratory, Santiago, Chile; Universidad San Sebastián, Santiago, Chile., Muena NA; Fundación Ciencia & Vida, Molecular Virology Laboratory, Santiago, Chile., Manuguerra JC; Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d'Intervention Biologique d'Urgence (CIBU), Paris, France., Jangra RK; Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA., Li S; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; School of Life Sciences, Tsinghua University, Beijing 100084, China., Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA., Tischler ND; Fundación Ciencia & Vida, Molecular Virology Laboratory, Santiago, Chile; Universidad San Sebastián, Santiago, Chile., Huiskonen JT; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Helsinki Institute of Life Science HiLIFE, Viikinkaari 1, 00014 University of Helsinki, Finland; Molecular and Integrative Biosciences Research Program, Faculty of Biological and Environmental Sciences, Viikinkaari 1, 00014 University of Helsinki, Finland., Rey FA; Institut Pasteur, Structural Virology Unit, and CNRS UMR 3569, Paris, France. Electronic address: rey@pasteur.fr., Guardado-Calvo P; Institut Pasteur, Structural Virology Unit, and CNRS UMR 3569, Paris, France. Electronic address: guardado@pasteur.fr.

Publikováno v: Cell [Cell] 2020 Oct 15; Vol. 183 (2), pp. 442-456.e16. Date of Electronic Publication: 2020 Sep 15.

The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins.

Autor: El Omari K; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Diamond Light Source Limited, Harwell Science and Innovation Campus, Didcot, OX11 0DE, UK., Li S; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; School of Life Sciences, Tsinghua University, 100084, Beijing, China., Kotecha A; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK., Walter TS; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK., Bignon EA; Fundación Ciencia & Vida, Laboratorio de Virología Molecular, Avenida Zañartu 1482, 7780272, Ñuñoa, Santiago, Chile., Harlos K; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK., Somerharju P; Department of Biochemistry and Developmental Biology, University of Helsinki, Haartmaninkatu 8, 00014, Helsinki, Finland., De Haas F; Thermo Fisher Scientific, Achtseweg Noorg 5, 5651 GG, Eindhoven, The Netherlands., Clare DK; Diamond Light Source Limited, Harwell Science and Innovation Campus, Didcot, OX11 0DE, UK., Molin M; Helsinki Institute of Life Science HiLIFE, Institute of Biotechnology, University of Helsinki, Viikinkaari 5, 00014, Helsinki, Finland., Hurtado F; Fundación Ciencia & Vida, Laboratorio de Virología Molecular, Avenida Zañartu 1482, 7780272, Ñuñoa, Santiago, Chile., Li M; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK., Grimes JM; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Diamond Light Source Limited, Harwell Science and Innovation Campus, Didcot, OX11 0DE, UK., Bamford DH; Molecular and Integrative Biosciences Research Program, University of Helsinki, Viikinkaari 1, 00014, Helsinki, Finland., Tischler ND; Fundación Ciencia & Vida, Laboratorio de Virología Molecular, Avenida Zañartu 1482, 7780272, Ñuñoa, Santiago, Chile. ntischler@cienciavida.org., Huiskonen JT; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK. juha.huiskonen@helsinki.fi.; Helsinki Institute of Life Science HiLIFE and Molecular and Integrative Biosciences Research Program, University of Helsinki, Viikinkaari 1, 00014, Helsinki, Finland. juha.huiskonen@helsinki.fi., Stuart DI; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK. dave@strubi.ox.ac.uk.; Diamond Light Source Limited, Harwell Science and Innovation Campus, Didcot, OX11 0DE, UK. dave@strubi.ox.ac.uk., Roine E; Molecular and Integrative Biosciences Research Program, University of Helsinki, Viikinkaari 1, 00014, Helsinki, Finland. elina.roine@helsinki.fi.

Publikováno v: Nature communications [Nat Commun] 2019 Feb 19; Vol. 10 (1), pp. 846. Date of Electronic Publication: 2019 Feb 19.

Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc.

Autor: Guardado-Calvo P; Institut Pasteur, Unité de Virologie Structurale, Département de Virologie, Paris, France.; CNRS UMR3569 Virologie, Paris, France., Bignon EA; Fundación Ciencia & Vida, Molecular Virology Laboratory, Santiago, Chile., Stettner E; Institut Pasteur, Unité de Virologie Structurale, Département de Virologie, Paris, France., Jeffers SA; Institut Pasteur, Unité de Virologie Structurale, Département de Virologie, Paris, France., Pérez-Vargas J; Institut Pasteur, Unité de Virologie Structurale, Département de Virologie, Paris, France.; CNRS UMR3569 Virologie, Paris, France., Pehau-Arnaudet G; Institut Pasteur, Ultrapole, Département de Biologie Cellulaire et Infection, Paris, France.; CNRS UMR 3528, Paris, France., Tortorici MA; Institut Pasteur, Unité de Virologie Structurale, Département de Virologie, Paris, France.; CNRS UMR3569 Virologie, Paris, France., Jestin JL; Institut Pasteur, Unité de Virologie Structurale, Département de Virologie, Paris, France., England P; CNRS UMR 3528, Paris, France.; Institut Pasteur, Plateforme de Biophysique des Macromolécules et de leurs Interactions, Département de Biologie Structurale et Chimie, Paris, France., Tischler ND; Fundación Ciencia & Vida, Molecular Virology Laboratory, Santiago, Chile., Rey FA; Institut Pasteur, Unité de Virologie Structurale, Département de Virologie, Paris, France.; CNRS UMR3569 Virologie, Paris, France.

Publikováno v: PLoS pathogens [PLoS Pathog] 2016 Oct 26; Vol. 12 (10), pp. e1005813. Date of Electronic Publication: 2016 Oct 26 (Print Publication: 2016).

Production and Purification of Hantavirus Glycoproteins in Drosophila melanogaster S2 Cells.

Autor: Meola A; G5 Structural Biology of Infectious Diseases, Institut Pasteur, Université Paris Cité, Paris, France., Guardado-Calvo P; G5 Structural Biology of Infectious Diseases, Institut Pasteur, Université Paris Cité, Paris, France. pablo.guardado-calvo@pasteur.fr.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2024; Vol. 2762, pp. 3-16.