Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bigboy H. Simbi"'
Autor:
Soraia Caetano-Silva, Bigboy H. Simbi, Neil Marr, Andrew Hibbert, Steve P. Allen, Andrew A. Pitsillides
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13220 (2021)
Mechanical cues play a vital role in limb skeletal development, yet their influence and underpinning mechanisms in the regulation of endochondral ossification (EO) processes are incompletely defined. Furthermore, interactions between endochondral gro
Externí odkaz:
https://doaj.org/article/f7be30201b6a47b0a4c85c8b38234fc4
Autor:
Patrick J. Kenny, Márta Korbonits, Jordan E. Read, Stijn J. M. Niessen, Victoria J Crossley, Samantha M. Mirczuk, Christopher J Scudder, Jacob T. Regan, Robert C. Fowkes, Imelda M. McGonnell, Craig A. McArdle, Holger A. Volk, Caroline P.D. Wheeler-Jones, David B. Church, Bigboy H. Simbi, Joe Fenn, Karen M. Richardson
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1076, p 1076 (2021)
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1076, p 1076 (2021)
Patients harbouring mutations in genes encoding C-type natriuretic peptide (CNP
NPPC) or its receptor guanylyl cyclase B (GC-B, NPR2) suffer from severe growth phenotypes
loss-of-function mutations cause achondroplasia, whereas gain-of-func
NPPC) or its receptor guanylyl cyclase B (GC-B, NPR2) suffer from severe growth phenotypes
loss-of-function mutations cause achondroplasia, whereas gain-of-func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593fe57698d38b23f163bc92b3a67c7b
Autor:
Robert C. Fowkes, Christopher J Scudder, Stijn J. M. Niessen, Bigboy H. Simbi, Natalie Welch, Imelda M. McGonnell, Kyriakos Grammatopoulos, Sophie Ringrose
Publikováno v:
Journal of the Endocrine Society
Endocrine Disrupting Chemicals (EDCs) are substances that have been increasingly implicated in many serious pathologies, such as tumor formation, metabolic, growth and reproductive disorders. The economic and health burden of exposure to these compou
Autor:
Jan-Hendrik Schroeder, Bigboy H Simbi, Louise Ford, Sara R Cole, Mark J Taylor, Charlotte Lawson, Rachel A Lawrence
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 11, p e1914 (2012)
Lymphatic filariasis is a major tropical disease caused by the parasite Brugia malayi. Microfilariae (Mf) circulate in the peripheral blood for 2-3 hours in synchronisation with maximal feeding of the mosquito vector. When absent from the peripheral
Externí odkaz:
https://doaj.org/article/25b7ac93d4934b2d87308fba184bb421
Publikováno v:
Biosensors
Volume 8
Issue 3
Biosensors, Vol 8, Iss 3, p 86 (2018)
Volume 8
Issue 3
Biosensors, Vol 8, Iss 3, p 86 (2018)
Cardiovascular diseases, including atherosclerosis, now account for more deaths in the Western world than from any other cause. Atherosclerosis has a chronic inflammatory component involving Th1 pro-inflammatory cytokines such as IFN-&gamma
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Autor:
Bigboy H. Simbi, Neil C. Stickland, Raymond Macharia, Stéphanie A. Bayol, Samantha J. Farrington
Publikováno v:
European Journal of Nutrition. 48:62-65
Obesity is a multi-factorial condition generally attributed to an unbalanced diet and lack of exercise. Recent evidence suggests that maternal malnutrition during pregnancy and lactation can also contribute to the development of obesity in offspring.
Autor:
Chrissy L. Hammond, Samantha J. Farrington, Stéphanie A. Bayol, Clare Ashton, Ibrahim Albokhadaim, Neil C. Stickland, Bigboy H. Simbi
Publikováno v:
Journal of Experimental Biology. 210:1735-1741
SUMMARYLarval muscle development in Atlantic salmon is known to be affected by temperature; however, the long term effects and possible mechanisms involved are less well understood. Therefore, the aim of this study was to evaluate the influence of eg
Publikováno v:
The Journal of Physiology. 567:951-961
We examined the effects of a maternal cafeteria diet on skeletal muscle and adipose tissue development in the offspring at weaning. Rats born to mothers fed the cafeteria diet either during gestation alone or during both gestation and lactation exhib
Autor:
Bigboy H. Simbi, Jan-Hendrik Schroeder, Sara R. Cole, Charlotte Lawson, Mark J. Taylor, Rachel A. Lawrence, Louise Ford
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 11, p e1914 (2012)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Lymphatic filariasis is a major tropical disease caused by the parasite Brugia malayi. Microfilariae (Mf) circulate in the peripheral blood for 2–3 hours in synchronisation with maximal feeding of the mosquito vector. When absent from the periphera
Publikováno v:
Endocrinology. 151(4)
With rising obesity rates, nonalcoholic fatty liver disease is predicted to become the main cause of chronic liver disease in the next decades. Rising obesity prevalence is attributed to changes in dietary habits with increased consumption of palatab