Zobrazeno 1 - 10
of 334
pro vyhledávání: '"Bifunctional chelator"'
Autor:
Piyapan Suwattananuruk, Sukanya Yaset, Chanisa Chotipanich, Angel Moldes-Anaya, Rune Sundset, Rodrigo Berzaghi, Stine Figenschau, Sandra Claes, Dominique Schols, Pornchai Rojsitthisak, Mathias Kranz, Opa Vajragupta
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-19 (2024)
Abstract Background This study aimed to develop a novel positron emission tomography (PET) tracer, [68Ga]Ga-TD-01, for CXCR4 imaging. To achieve this goal, the molecular scaffold of TIQ15 was tuned by conjugation with the DOTA chelator to make it sui
Externí odkaz:
https://doaj.org/article/c3db7fc51fd5432a9dad7507f7eb9509
Autor:
Mengting Li, Sheng Wang, Qunshou Kong, Xinyi Cheng, Huanhuan Yan, Yao Xing, Xiaoli Lan, Dawei Jiang
Publikováno v:
View, Vol 4, Iss 5, Pp n/a-n/a (2023)
Abstract In recent years, radiometals have been successfully applied to medicine because of their breadth of decay properties and increased production and availability. Bifunctional chelators play a key role in radiometal‐based radiopharmaceuticals
Externí odkaz:
https://doaj.org/article/e9eb42170e1d47e48bfeafc35e989b9e
Autor:
Xiaoguang Liu, Lixing Chen, Yuying Li, Chuanchuan He, Xiaojuan Zhang, Huimin Zhou, Guangfa Bao, Xiaohua Zhu, Guangya Xiang, Xiang Ma
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115114- (2023)
Bifunctional chelators (BFCs), which link metallic radionuclide and a targeting vector, are some of the most crucial components of metallic radionuclide-based radiopharmaceuticals for positron-emission computed tomography (PET) imaging. In this study
Externí odkaz:
https://doaj.org/article/a7d339dcd1464307b373f573563fcc22
Autor:
A. G. Polivanova, I. N. Solovieva, D. O. Botev, D. Y. Yuriev, A. N. Mylnikova, M. S. Oshchepkov
Publikováno v:
Тонкие химические технологии, Vol 17, Iss 2, Pp 107-130 (2022)
Objectives. The chemistry of 67Ga and 68Ga radionuclides plays a key role in nuclear medicine for applications in radiopharmaceuticals, in particular, in noninvasive in vivo molecular imaging techniques. The use of radiometals for labeling biomolecul
Externí odkaz:
https://doaj.org/article/c053bbe8c80d4b9a9bcdc5a489539ea9
Akademický článek
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Akademický článek
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Autor:
Erika Murce, Stephen Ahenkorah, Savanne Beekman, Maryana Handula, Debra Stuurman, Corrina de Ridder, Frederik Cleeren, Yann Seimbille
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 882 (2023)
Bifunctional chelators (BFCs) are a key element in the design of radiopharmaceuticals. By selecting a BFC that efficiently complexes diagnostic and therapeutic radionuclides, a theranostic pair possessing almost similar biodistribution and pharmacoki
Externí odkaz:
https://doaj.org/article/f4b0bf3eefcc483bac911402c61e20c0
Publikováno v:
Molecules, Vol 28, Iss 1, p 203 (2022)
The positron-emitting radionuclide gallium-68 has become increasingly utilised in both preclinical and clinical settings with positron emission tomography (PET). The synthesis of radiochemically pure gallium-68 radiopharmaceuticals relies on careful
Externí odkaz:
https://doaj.org/article/bb97ba369ab34f0282e93869209124af
Akademický článek
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Autor:
Alexandra Foster, Shubhanchi Nigam, David S Tatum, Itay Raphael, Jide Xu, Rajeev Kumar, Elizabeth Plakseychuk, Joseph D Latoche, Sarah Vincze, Bo Li, Rajan Giri, Lauren H McCarl, Robert Edinger, Murat Ak, Vishal Peddagangireddy, Lesley M Foley, T Kevin Hitchens, Rivka R Colen, Ian F Pollack, Ashok Panigrahy, Darren Magda, Carolyn J Anderson, W Barry Edwards, Gary Kohanbash
Publikováno v:
EBioMedicine, Vol 71, Iss , Pp 103571- (2021)
Background: Malignant gliomas are deadly tumours with few therapeutic options. Although immunotherapy may be a promising therapeutic strategy for treating gliomas, a significant barrier is the CD11b+ tumour-associated myeloid cells (TAMCs), a heterog
Externí odkaz:
https://doaj.org/article/262ba25f595340aea3143132472fdff3