Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Bifang, He"'
Autor:
Min Li, Yifei Wu, Bowen Li, Chunying Lu, Guifen Jian, Xing Shang, Heng Chen, Jian Huang, Bifang He
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3625-3633 (2024)
Peptides, as small molecular compounds, exhibit prominent advantages in the inhibition of coronaviruses due to their safety, efficacy, and specificity, holding great promise as drugs against coronaviruses. The rapid and efficient determination of the
Externí odkaz:
https://doaj.org/article/6a3b86a887d84f3cb3030e05d4ea0cf7
Autor:
Qianyue Zhang, Xue Chen, Bowen Li, Chunying Lu, Shanshan Yang, Jinjin Long, Heng Chen, Jian Huang, Bifang He
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-9 (2022)
Measurement(s) Inhibition effect of anti-coronavirus peptide Technology Type(s) Antiviral assay
Externí odkaz:
https://doaj.org/article/eb9ae2f620a54a00bce4f50db00ae7b6
Autor:
Bifang He, Bowen Li, Xue Chen, Qianyue Zhang, Chunying Lu, Shanshan Yang, Jinjin Long, Lin Ning, Heng Chen, Jian Huang
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Monoclonal antibody drugs targeting the PD-1/PD-L1 pathway have showed efficacy in the treatment of cancer patients, however, they have many intrinsic limitations and inevitable drawbacks. Peptide inhibitors as alternatives might compensate for the d
Externí odkaz:
https://doaj.org/article/e0edea35a6b4449fafc41215a60ffec6
Publikováno v:
PeerJ, Vol 10, p e13581 (2022)
Diabetes mellitus (DM) is a chronic metabolic disease that has been a major threat to human health globally, causing great economic and social adversities. The oral administration of anti-diabetic peptide drugs has become a novel route for diabetes t
Externí odkaz:
https://doaj.org/article/6052112fb54e4facbafbef4ff1a73a31
Autor:
Xue Chen, Qianyue Zhang, Bowen Li, Chunying Lu, Shanshan Yang, Jinjin Long, Bifang He, Heng Chen, Jian Huang
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Blood-brain barrier (BBB) is a major barrier to drug delivery into the brain in the treatment of central nervous system (CNS) diseases. Blood-brain barrier penetrating peptides (BBPs), a class of peptides that can cross BBB through various mechanisms
Externí odkaz:
https://doaj.org/article/1de1b85388e04f73aabb18805dfe3813
Publikováno v:
PeerJ, Vol 9, p e11887 (2021)
Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated (Cas) proteins constitute the CRISPR-Cas systems, which play a key role in prokaryote adaptive immune system against invasive foreign elements. In recent years, t
Externí odkaz:
https://doaj.org/article/119ba079950f4235a8f90bfd90aefa74
Publikováno v:
PeerJ, Vol 7, p e7131 (2019)
Selection from phage display libraries empowers isolation of high-affinity ligands for various targets. However, this method also identifies propagation-related target-unrelated peptides (PrTUPs). These false positive hits appear because of their amp
Externí odkaz:
https://doaj.org/article/366c92a40d3b4c11a4147fc4685c733d
Publikováno v:
BIOCELL. 46:547-557
Autor:
Chunying Lu, Bowen Li, Qianyue Zhang, Xue Chen, Yajing Pang, Fengmei Lu, Yifei Wu, Min Li, Bifang He, Heng Chen
Publikováno v:
Cerebral cortex (New York, N.Y. : 1991).
BrainAGE is a commonly used machine learning technique to measure the accelerated/delayed development pattern of human brain structure/function with neuropsychiatric disorders. However, recent studies have shown a systematic bias (“regression towar
Autor:
Jinjin Long, Fengmei Lu, Shanshan Yang, Qianyue Zhang, Xue Chen, Yajing Pang, Min Wang, Bifang He, Heng Liu, Xujun Duan, Huafu Chen, Shaobing Ye, Heng Chen
Publikováno v:
Human brain mapping. 44(1)
Studies have reported that different brain regions/connections possess distinct frequency properties, which are related to brain function. Previous studies have proposed altered brain activity frequency and frequency-specific functional connectivity