Výsledky vyhledávání - "Bieuwke S. Dragt"

Akademický článek

The shear stress-induced transcription factor KLF2 affects dynamics and angiopoietin-2 content of Weibel-Palade bodies.

Autor: Ellen L van Agtmaal, Ruben Bierings, Bieuwke S Dragt, Thomas A Leyen, Mar Fernandez-Borja, Anton J G Horrevoets, Jan Voorberg

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38399 (2012)

BACKGROUND: The shear-stress induced transcription factor KLF2 has been shown to induce an atheroprotective phenotype in endothelial cells (EC) that are exposed to prolonged laminar shear. In this study we characterized the effect of the shear stress

Externí odkaz: https://doaj.org/article/28dce1412ae44a3c8a2dd2d387ab2c3f

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Regulation of VDR expression in rat and human intestine and liver – Consequences for CYP3A expression

Autor: Geny M. M. Groothuis, Robert J. Porte, Bieuwke S. Dragt, Ansar A. Khan

Publikováno v: Toxicology in Vitro, 24(3), 822-829. PERGAMON-ELSEVIER SCIENCE LTD

The vitamin D receptor (VDR) regulates the expression of drug metabolizing enzymes and transporters in intestine and liver, but the regulation of VDR expression in intestine and liver is incompletely understood. We studied the regulation of VDR mRNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d324d9d4c3e52e0d1cd816853191ea8
https://doi.org/10.1016/j.tiv.2009.12.011

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A physiological role for glucuronidated thyroid hormones: Preferential uptake by H9c2(2-1) myotubes

Autor: Peter H.M. Klaren, Sabine M. van der Heide, Bieuwke S. Dragt, Brian J. L. J. Joosten, Maria E. Everts

Publikováno v: Molecular and Cellular Endocrinology, 264, 1-2, pp. 109-17
Molecular and Cellular Endocrinology, 264, 109-17

Contains fulltext : 35115.pdf (Publisher’s version ) (Closed access) Conjugation reactions are important pathways in the peripheral metabolism of thyroid hormones. Rat cardiac fibroblasts produce and secrete glucuronidated thyroxine (T4G) and 3,3',

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d39e88ff9be85c585ef01692fbb087ab
https://hdl.handle.net/2066/35115

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Effect of laminar shear stress on the distribution of Weibel-Palade bodies in endothelial cells

Autor: Bas de Laat, Jan Voorberg, Ellen L. van Agtmaal, Bieuwke S. Dragt

Publikováno v: Thrombosis Research, 130(5), 741-745. Elsevier Science
Thrombosis research, 130(5), 741-745. Elsevier Limited

Background: Vascular endothelial cells (ECs) provide a highly interactive barrier between blood and the underlying tissues. It is well established that ECs exposed to laminar flow align in the direction of flow and also arrange their actin stress fib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcdc99bb445b71d3ba40c66cba12ee96
https://cris.maastrichtuniversity.nl/en/publications/da4f2555-c448-4a61-86ab-762646798766

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Formation of platelet-binding von Willebrand factor strings on non-endothelial cells

Autor: Karine M. Valentijn, Jan Voorberg, Jeroen Eikenboom, Jack A. Valentijn, Pieter H. Reitsma, Jiong-Wei Wang, Bieuwke S. Dragt

Publikováno v: Journal of thrombosis and haemostasis, 10(10), 2168-2178. Wiley-Blackwell

Summary. Background and Objective: Von Willebrand factor (VWF) forms strings on activated vascular endothelial cells that recruit platelets and initiate clot formation. Alterations in VWF strings may disturb hemostasis. This study was aimed at develo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90fd1ec3838c239bb2b285262224bcda
https://hdl.handle.net/1887/97884

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Proteomic Screen Identifies IGFBP7 as a Novel Component of Endothelial Cell-Specific Weibel-Palade Bodies

Autor: Ruben Bierings, I. Dienava-Verdoold, Astrid Kragt, Dorothee van Breevoort, Karine M. Valentijn, Jacqueline W.T.M. Klein Gebbinck, Jan Voorberg, Alexander B. Meijer, Jeroen Eikenboom, Ellen L. van Agtmaal, Anton J.G. Horrevoets, Bieuwke S. Dragt, Mar Fernandez-Borja

Publikováno v: Journal of Proteome Research, 11(5), 2925-2936. American Chemical Society
van Breevoort, D, van Agtmaal, E L, Dragt, B S, Gebbinck, J K, Dienava-Verdoold, I, Kragt, A, Bierings, R, Horrevoets, A J G, Valentijn, K M, Eikenboom, J C, Fernandez-Borja, M, Meijer, A B & Voorberg, J 2012, ' Proteomic Screen Identifies IGFBP7 as a Novel Component of Endothelial Cell-Specific Weibel-Palade Bodies ', Journal of Proteome Research, vol. 11, no. 5, pp. 2925-2936 . https://doi.org/10.1021/pr300010r
Journal of proteome research, 11(5), 2925-2936. American Chemical Society
Journal of Proteome Research, 11(5), 2925-2936

Vascular endothelial cells contain unique storage organelles, designated Weibel-Palade bodies (WPBs), that deliver inflammatory and hemostatic mediators to the vascular lumen in response to agonists like thrombin and vasopressin. The main component o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce276742366e350b9d07dae5aa7697ce
https://research.vumc.nl/en/publications/fa1c1ea3-9400-423d-9c50-2ceb011db419

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The shear stress-induced transcription factor KLF2 affects dynamics and angiopoietin-2 content of Weibel-Palade bodies

Autor: Jan Voorberg, Ellen L. van Agtmaal, Ruben Bierings, Mar Fernandez-Borja, Thomas A. Leyen, Anton J.G. Horrevoets, Bieuwke S. Dragt

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38399 (2012)
PLoS ONE, 7(6):e38399. Public Library of Science
PLoS ONE
PLoS ONE, 7(6). Public Library of Science
van Agtmaal, E L, Bierings, R, Dragt, B S, Leyen, T A, Fernandez-Borja, M, Horrevoets, A J G & Voorberg, J 2012, ' The Shear Stress-Induced Transcription Factor KLF2 Affects Dynamics and Angiopoietin-2 Content of Weibel-Palade Bodies ', PLoS ONE, vol. 7, no. 6, e38399 . https://doi.org/10.1371/journal.pone.0038399

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c6252323c95e5b3bf24a9999929690
http://europepmc.org/articles/PMC3371018?pdf=render

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