Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Bieong-Kil Kim"'
Autor:
Shobha Regmi, Shiva Pathak, Tung Pham Thanh, Tiep Tien Nguyen, Jong-Hyuk Sung, Simmyung Yook, Jong Oh. Kim, Chul Soon Yong, Inho Choi, Kyoung-Oh Doh, Pil-Hoon Park, Jun-Beom Park, Yoojin Seo, Bieong-Kil Kim, Dong-Mok Lee, Ik-Jae Moon, Hyung-Sik Kim, Jee-Heon Jeong
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
Abstract Background Systemic inflammatory response syndrome (SIRS) is common in severe fulminant hepatic failure (FHF) and has a high mortality rate (20–50%) due to irreversible cerebral edema or sepsis. Stem cell-based treatment has emerged as a p
Externí odkaz:
https://doaj.org/article/7f2d9c25befd4154adca588c99ed3e06
Publikováno v:
Letters in Organic Chemistry. 16:615-618
Gene therapy is a powerful technology for treating incurable and hereditary disease in humans. In the recent years, a lot of studies have been done on the development of DNA carriers. Nonviral vectors, like liposomes, polymers, and micelles, has beco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b945b5d03e6539d27514e4e236d8bfc
https://doi.org/10.2174/1570178615666181022143627
https://doi.org/10.2174/1570178615666181022143627
Publikováno v:
Cancer gene therapy
The excitement surrounding the potential of gene therapy has been tempered due to the challenges that have thus far limited its successful implementation in the clinic such as issues regarding stability, transfection efficiency, and toxicity. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71bc9c24803801561023a189e5e4cf9
https://doi.org/10.1038/s41417-017-0004-z
https://doi.org/10.1038/s41417-017-0004-z
Autor:
Yoon Yeo, Bieong Kil Kim, Ji Young Yhee, Ick Chan Kwon, Sun Hwa Kim, Gijung Kwak, Dongkyu Kim
Publikováno v:
ACS Biomaterials Science & Engineering. 3:990-999
We report unique bioactivity of a polycation-polyanion complex with potential utility for cancer therapy. A complex of disulfide-crosslinked polyethyleneimine (CLPEI), a polycation used for gene complexation, and dermatan sulfate (DS), an anionic pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2202e6a630413735caefaef1ce72b48b
https://doi.org/10.1021/acsbiomaterials.7b00207
https://doi.org/10.1021/acsbiomaterials.7b00207
Autor:
Pil-Hoon Park, Chul Soon Yong, Jong-Hyuk Sung, Tung Pham Thanh, Tiep Tien Nguyen, Shobha Regmi, Yoojin Seo, Simmyung Yook, Jee-Heon Jeong, Shiva Pathak, Inho Choi, Jun-Beom Park, Kyoung-Oh Doh, Dong-Mok Lee, Jong Oh Kim, Bieong-Kil Kim, Hyung Sik Kim, Ik-Jae Moon
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
BackgroundSystemic inflammatory response syndrome (SIRS) is common in severe fulminant hepatic failure (FHF) and has a high mortality rate (20–50%) due to irreversible cerebral edema or sepsis. Stem cell-based treatment has emerged as a promising a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f53804bddc161f44128b4fae680226
http://europepmc.org/articles/PMC6794806
http://europepmc.org/articles/PMC6794806
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1858:3017-3023
Cholesterol is an important cell membrane component and has been used as co-lipid for cationic liposome to enhance gene delivery. However, the role of cholesterol in transfection efficiency has not been fully understood. In this study, transfection e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be18e2079cc76b6f2071df74c81831fe
https://doi.org/10.1016/j.bbamem.2016.09.013
https://doi.org/10.1016/j.bbamem.2016.09.013
Publikováno v:
ACS Biomaterials Science & Engineering. 2:2294-2303
Polymeric nanoparticles (NPs) are decorated with various types of molecules to control their functions and interactions with specific cells. We previously used polydopamine (pD) to prime-coat poly(lactic-co-glycolic acid) (PLGA) NPs and conjugated fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b07222d8b501430fba20acf06cecb06
https://doi.org/10.1021/acsbiomaterials.6b00497
https://doi.org/10.1021/acsbiomaterials.6b00497
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1848(10):1996-2001
The effects of lipid compositions on their physicochemical properties and transfection efficiencies were investigated. Four liposome formulations with different 1,2-dioleoyl-3-trimethylammoniumpropane (DOTAP) to dioleoylphosphatidylethanolamine (DOPE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64255266b7059a4f2fe787d4af75c4c4
Autor:
Bieong-Kil Kim, Yoon Yeo
Publikováno v:
The AAPS Journal. 17:1096-1104
Biomaterials used as drug carriers are often considered inactive and assumed to have no other roles than modifying pharmacokinetics and biodistribution of a drug. On the other hand, there are several examples in which the carrier materials show bioac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163154415227ed17374ed1c59f784ed5
https://doi.org/10.1208/s12248-015-9789-6
https://doi.org/10.1208/s12248-015-9789-6
Publikováno v:
Biomaterials
Polyethyleneimine (PEI) is widely used for the delivery of nucleic acids, but its clinical application is limited due to high cytotoxicity and instability in biological fluids. To overcome these challenges, linear PEI (2.5 kDa) was modified with lith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a0d2856592fec3d505d7e162a0da28
https://doi.org/10.1016/j.biomaterials.2019.119296
https://doi.org/10.1016/j.biomaterials.2019.119296