Implantation of engineered adipocytes that outcompete tumors for resources suppresses cancer progression.

Autor: Nguyen HP; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Sheng R; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Murray E; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Ito Y; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Bruck M; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Biellak C; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., An K; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Lynce F; Dana-Farber Cancer Institute, Harvard University, Boston, MA 02215, USA., Dillon DA; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA., Magbanua MJM; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 04158, USA., Huppert LA; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Hammerlindl H; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158, USA., Esserman L; Department of Surgery, University of California, San Francisco, San Francisco, CA 94158, USA., Rosenbluth JM; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub - San Francisco, San Francisco, CA 94158, USA., Ahituv N; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 29. Date of Electronic Publication: 2023 Mar 29.