A randomized controlled non-inferiority trial of placebo versus macrolide antibiotics for Mycoplasma pneumoniae infection in children with community-acquired pneumonia: trial protocol for the MYTHIC Study.

Autor: Meyer Sauteur PM; Division of Infectious Diseases and Hospital Epidemiology, Children's Research Center, University Children's Hospital Zurich, University of Zurich, Steinwiesstrasse 75, Zurich, CH-8032, Switzerland. patrick.meyersauteur@kispi.uzh.ch., Seiler M; Emergency Department, Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland., Tilen R; Division of Infectious Diseases and Hospital Epidemiology, Children's Research Center, University Children's Hospital Zurich, University of Zurich, Steinwiesstrasse 75, Zurich, CH-8032, Switzerland., Osuna E; Division of Infectious Diseases and Hospital Epidemiology, Children's Research Center, University Children's Hospital Zurich, University of Zurich, Steinwiesstrasse 75, Zurich, CH-8032, Switzerland., von Wantoch M; Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland., Sidorov S; Division of Infectious Diseases and Hospital Epidemiology, Children's Research Center, University Children's Hospital Zurich, University of Zurich, Steinwiesstrasse 75, Zurich, CH-8032, Switzerland., Aebi C; Division of Pediatric Infectious Disease, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Agyeman P; Division of Pediatric Infectious Disease, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Barbey F; Children's Hospital Aarau, Aarau, Switzerland., Bielicki JA; Department of Infectious Diseases and Vaccinology, University of Basel Children's Hospital (UKBB), Basel, Switzerland., Coulon L; Department of Pediatrics, Department Mother-Woman-Child, Lausanne University Hospital, Lausanne, Switzerland., Deubzer B; Department of Pediatrics, Cantonal Hospital Graubuenden, Chur, Switzerland., Donas A; Emergency Department, Children's Hospital of Central Switzerland, Lucerne, Switzerland., Heininger U; Department of Infectious Diseases and Vaccinology, University of Basel Children's Hospital (UKBB), Basel, Switzerland., Keitel K; Division of Pediatric Emergency Medicine, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Köhler H; Children's Hospital Aarau, Aarau, Switzerland., Kottanattu L; Institute of Pediatrics of Southern Switzerland, EOC, Bellinzona, Switzerland., Lauener R; Children's Hospital of Eastern Switzerland St. Gallen, St. Gallen, Switzerland., Niederer-Loher A; Children's Hospital of Eastern Switzerland St. Gallen, St. Gallen, Switzerland., Posfay-Barbe KM; Children's Hospital of Geneva, Geneva University Hospitals, Geneva, Switzerland., Tomaske M; Department of Pediatrics, Triemli Hospital Zurich, Zurich, Switzerland., Wagner N; Children's Hospital of Geneva, Geneva University Hospitals, Geneva, Switzerland., Zimmermann P; Department of Pediatrics, University of Fribourg and Fribourg Hospital, Fribourg, Switzerland., Zucol F; Department of Pediatrics, Cantonal Hospital Winterthur, Winterthur, Switzerland., von Felten S; Department of Biostatistics at Epidemiology, Biostatistics and Prevention Institute (EBPI), University of Zurich, Zurich, Switzerland., Berger C; Division of Infectious Diseases and Hospital Epidemiology, Children's Research Center, University Children's Hospital Zurich, University of Zurich, Steinwiesstrasse 75, Zurich, CH-8032, Switzerland.

Publikováno v: Trials [Trials] 2024 Oct 03; Vol. 25 (1), pp. 655. Date of Electronic Publication: 2024 Oct 03.

Pharmacokinetics-Based Pediatric Dose Evaluation and Optimization Using Saliva - A Case Study.

Autor: Anliker-Ort M; Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., Rodieux F; Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland.; Division of Clinical Pharmacology and Toxicology, Department of Anesthesiology, Pharmacology, Intensive Care and Emergency Medicine, Geneva University Hospitals, Geneva, Switzerland., Ziesenitz VC; Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland.; Pediatric and Congenital Cardiology, University Children's Hospital Heidelberg, Heidelberg, Germany., Atkinson A; Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland.; Infectious Diseases Division, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Bielicki JA; Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland.; Pediatric Infectious Diseases, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., Erb TO; Pediatric Anesthesiology, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., Gürtler N; Department of Otolaryngology, Head and Neck Surgery, University Hospital Basel, University of Basel, Basel, Switzerland., Holland-Cunz S; Pediatric Surgery, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., Duthaler U; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland., Rudin D; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland., Haschke M; Clinical Pharmacology and Toxicology, Department of General Internal Medicine, University Hospital Bern, University of Bern, Bern, Switzerland., van den Anker J; Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., Pfister M; Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., Gotta V; Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland.

Publikováno v: Journal of clinical pharmacology [J Clin Pharmacol] 2024 Jul; Vol. 64 (7), pp. 810-819. Date of Electronic Publication: 2024 Mar 18.

Infection Control in the NICU: The Roles of Surveillance Cultures.

Autor: Schlaeppi C; From the Infectious Disease and Vaccinology Unit.; Department of Clinical Research, University of Basel, Basel, Switzerland., Minotti C; From the Infectious Disease and Vaccinology Unit.; Department of Clinical Research, University of Basel, Basel, Switzerland.; Paediatric Research Centre, University Children's Hospital Basel, Basel, Switzerland., Bielicki JA; From the Infectious Disease and Vaccinology Unit.; Department of Clinical Research, University of Basel, Basel, Switzerland.; Paediatric Research Centre, University Children's Hospital Basel, Basel, Switzerland.; Centre for Neonatal and Paediatric Infection, St George's, University of London, London, United Kingdom.

Publikováno v: The Pediatric infectious disease journal [Pediatr Infect Dis J] 2024 May 01; Vol. 43 (5), pp. e175-e177. Date of Electronic Publication: 2024 Feb 22.

Swissped-RECOVERY: masked independent adjudication for the interpretation of non-randomised treatment in a two-arm open-label randomised controlled trial (methylprednisolone vs immunoglobulins) in Paediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS) involving 10 secondary and tertiary paediatric hospitals in Switzerland.

Autor: Schöbi N; Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Sanchez C; Paediatric Research Centre, University Children's Hospital Basel, University of Basel, Basel, Switzerland., Welzel T; Paediatric Research Centre, University Children's Hospital Basel, University of Basel, Basel, Switzerland.; Pediatric Rheumatology, University Children's Hospital Basel, University of Basel, Basel, Switzerland., Bamford A; Paediatric Infectious Diseases, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.; Infection, Immunity and Inflammation, UCL Great Ormond Street Institute of Child Health, London, UK., Webb K; Division of Paediatric Rheumatology, School of Child and Adolescent Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa., Rojo P; Pediatrics, Hospital Universitario Doce de Octubre. Universidad Complutense. Instituto de Investigación 12 Octubre, Madrid, Spain., Tremoulet A; Paediatrics, University of California San Diego, Rady Children's Hospital San Diego, San Diego, California, USA., Atkinson A; Paediatric Research Centre, University Children's Hospital Basel, University of Basel, Basel, Switzerland.; Infectious Diseases, Washington University in St. Louis School of Medicine, St. Louis, St Louis, Missouri, USA., Schlapbach LJ; Department of Intensive Care and Neonatalogy, and Children's Research Center, University Children's Hospital Zürich, Zurich, Switzerland.; Child Health Research Centre, The University of Queensland, and Paediatric Intensive Care Unit, Queensland Children's Hospital, Saint Lucia, Queensland, Australia., Bielicki JA; Paediatric Research Centre, University Children's Hospital Basel, University of Basel, Basel, Switzerland JuliaAnna.Bielicki@ukbb.ch.; Centre for Neonatal and Paediatric Infection, St George's University, London, UK.

Publikováno v: BMJ open [BMJ Open] 2024 Apr 25; Vol. 14 (4), pp. e078137. Date of Electronic Publication: 2024 Apr 25.

COVID-19 Vaccine Acceptance Among Parents of Children With Multisystem Inflammatory Syndrome in Children.

Autor: Blanchard-Rohner G; From the Division of General Pediatrics, Department of Child, Woman and Adolescent Medicine, Pediatric Immunology and Vaccinology Unit, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland., Sanchez C; Paediatric Research Centre, University Children's Hospital Basel, University of Basel, Basel, Swizerland., Andre MC; Division of Respiratory and Critical Care Medicine, University Children's Hospital Basel, University of Basel, Basel, Switzerland.; Department of Pediatric Hematology and Oncology, University Children's Hospital, Eberhard Karls University, Tuebingen, Germany., Bressieux-Degueldre S; Department of Women-Mother-Child, Paediatric Cardiology Unit, University Hospital of Lausanne and Lausanne University, Lausanne, Switzerland., Grazioli S; Division of Neonatal and Pediatric Intensive Care, Department of Child, Woman and Adolescent Medicine, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland., Perez MH; Department of Women-Mother-Child, Paediatric Intensive and Intermediate Care Units, University Hospital of Lausanne and Lausanne University, Lausanne, Switzerland., Wütz D; Division of Pediatric Cardiology, Pediatric Heart Center, University Children's Hospital Zurich, Zurich, Switzerland., Schöbi N; Division of Pediatric Infectious Diseases, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Welzel T; Paediatric Research Centre, University Children's Hospital Basel, University of Basel, Basel, Swizerland.; Division of Pediatric Rheumatology, University Children's Hospital Basel, University of Basel, Basel, Switzerland., Atkinson A; Paediatric Research Centre, University Children's Hospital Basel, University of Basel, Basel, Swizerland.; Division of Infectious Diseases, Washington University in St. Louis School of Medicine, St. Louis, Missouri., Schlapbach LJ; Department of Intensive Care and Neonatology, Children`s Research Center, University Children's Hospital Zurich, Zurich, Switzerland.; Paediatric Intensive Care Unit, Child Health Research Centre, Queensland Children's Hospital, The University of Queensland, Brisbane, Australia., Bielicki JA; Centre for Neonatal and Paediatric Infection, St George's University, London, United Kingdom., Trück J; Divisions of Allergy and Immunology, Children's Research Center, University Children's Hospital Zurich, University of Zurich (UZH), Zurich, Switzerland.

Publikováno v: The Pediatric infectious disease journal [Pediatr Infect Dis J] 2024 Apr 01; Vol. 43 (4), pp. 361-364. Date of Electronic Publication: 2024 Jan 15.