Acute cell stress screen with supervised machine learning predicts cytotoxicity of excipients

Autor: Bieberich, Andrew A., Rajwa, Bartek, Irvine, Allison, Fatig, Raymond O., III, Fekete, Alexander, Jin, Hong, Kutlina, Elena, Urban, Laszlo

Publikováno v: In Journal of Pharmacological and Toxicological Methods September-October 2021 111

Optimization of the 4-anilinoquin(az)oline scaffold as epidermal growth factor receptor (EGFR) inhibitors for chordoma utilizing a toxicology profiling assay platform.

Autor: Bieberich, Andrew A.¹ (AUTHOR), Laitinen, Tuomo² (AUTHOR), Maffuid, Kaitlyn³ (AUTHOR), Fatig III, Raymond O.¹ (AUTHOR), Torrice, Chad D.³ (AUTHOR), Morris, David C.⁴ (AUTHOR), Crona, Daniel J.^3,5 (AUTHOR), Asquith, Christopher R. M.^2,6,7 (AUTHOR) christopher.asquith@uef.fi

Publikováno v: Scientific Reports. 7/27/2022, Vol. 12 Issue 1, p1-14. 14p.

Mitochondrial Inheritance in Schistosoma mansoni: Mitochondrial Variable Number Tandem Repeat Mutation Produces Noise on Top of the Signal

Autor: Bieberich, Andrew A., Minchella, Dennis J.

Publikováno v: The Journal of Parasitology, 2001 Oct 01. 87(5), 1011-1015.

Externí odkaz: https://www.jstor.org/stable/3285224

A synergistic antiproliferation effect of curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: unique signaling not explained by the effects of either compound alone

Autor: Jo Davisson V, Xu Zhidong, VanHorn Justin F, Harvey Kevin A, Terry Colin, Bieberich Andrew A, Altenburg Jeffrey D, Siddiqui Rafat A

Publikováno v: BMC Cancer, Vol 11, Iss 1, p 149 (2011)

Abstract Background Breast cancer is a collection of diseases in which molecular phenotypes can act as both indicators and mediators of therapeutic strategy. Therefore, candidate therapeutics must be assessed in the context of multiple cell lines wit

Externí odkaz: https://doaj.org/article/940d09b73237492d96c52a0ff391dd9f

A community computational challenge to predict the activity of pairs of compounds

Autor: Bansal, M, Yang, J, Karan, C, Menden, Mp, Costello, Jc, Tang, H, Xiao, G, Li, Y, Allen, J, Zhong, R, Chen, B, Kim, M, Wang, T, Heiser, Lm, Realubit, R, Mattioli, M, Alvarez, Mj, Shen, Y, Gallahan, D, Singer, D, Saez Rodriguez, J, Xie, Y, Stolovitzky, G, Califano, A, NCI DREAM Community: Jean Paul Abbuehl, NCI DREAM C. o. m. m. u. n. i. t. y., Jeffrey, Allen, Altman, Russ B., Shawn, Balcome, Mukesh, Bansal, Ana, Bell, Andreas, Bender, Bonnie, Berger, Jonathan, Bernard, Bieberich, Andrew A., Giorgos, Borboudakis, Andrea, Califano, Christina, Chan–, Beibei, Chen, Ting Huei Chen, Jaejoon, Choi, Luis Pedro Coelho, Costello, James C., Creighton, Chad J., Will, Dampier, Jo Davisson, V., Raamesh, Deshpande, Lixia, Diao, DI CAMILLO, Barbara, Murat, Dundar, Adam, Ertel, Cellworks, Group, Daniel, Gallahan, Goswami, Chirayu P., Assaf, Gottlieb, Gould, Michael N., Jonathan, Goya, Michael, Grau, Gray, Joe W., Heiser, Laura M., Hejase, Hussein A., Hoffmann, Michael F., Krisztian, Homicsko, Max, Homilius, Woochang, Hwang, Ijzerman, Adriaan P., Olli, Kallioniemi, Bilge, Karacali, Charles, Karan, Samuel, Kaski, Junho, Kim, Minsoo, Kim, Arjun, Krishnan, Junehawk, Lee, Young Suk Lee, Lenselink, Eelke B., Peter, Lenz, Lang, Li, Jun, Li, Yajuan, Li, Han, Liang, Michela, Mattioli, Menden, Michael P., John Patrick Mpindi, Myers, Chad L., Newton, Michael A., Overington, John P., Juuso, Parkkinen, Prill, Robert J., Jian, Peng, Richard, Pestell, Peng, Qiu, Bartek, Rajwa, Ronald, Realubit, Anguraj, Sadanandam, Julio Saez Rodriguez, Sambo, Francesco, Dinah, Singer, Gustavo, Stolovitzky, Arvind, Sridhar, Wei, Sun, Hao, Tang, Toffolo, GIANNA MARIA, Aydin, Tozeren, Troyanskaya, Olga G., Ioannis, Tsamardinos, van Vlijmen, Herman W. T., Tao, Wang, Wen, Wang, Wegner, Joerg K., Krister, Wennerberg, van Westen, Gerard J. P., Tian, Xia, Guanghua, Xiao, Yang, Xie, Jichen, Yang, Yang, Yang, Victoria, Yao, Yuan, Yuan, Haoyang, Zeng, Shihua, Zhang, Junfei, Zhao, Jian, Zhou, Rui, Zhong

Publikováno v: PMC

Recent therapeutic successes have renewed interest in drug combinations, but experimental screening approaches are costly and often identify only small numbers of synergistic combinations. The DREAM consortium launched an open challenge to foster the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6036fbfc7df321554faadce111f774d4
http://hdl.handle.net/1721.1/110181