Computational Identification of Post Translational Modification Regulated RNA Binding Protein Motifs.

Autor: Andrew S Brown, Bidyut K Mohanty, Philip H Howe

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0137696 (2015)

RNA and its associated RNA binding proteins (RBPs) mitigate a diverse array of cellular functions and phenotypes. The interactions between RNA and RBPs are implicated in many roles of biochemical processing by the cell such as localization, protein t

Externí odkaz: https://doaj.org/article/670c079c61b54ab0a4dbe2c996c74a50

Yeast Sphingolipid Phospholipase Gene ISC1 Regulates the Spindle Checkpoint by a CDC55-Dependent Mechanism

Autor: Bachar H. Hassan, Steven Vestergaard Rødkær, Baasil Shariff, Yusuf A. Hannun, Ashraf A. Shamssedine, W. Jim Zheng, Justin Snider, Eun-Mi Jeong, Bidyut K. Mohanty, Nabil Matmati, Nils J. Færgeman, Lina M. Obeid, Guocai Chen, Martin Røssel-Larsen, Jihui Ren

Publikováno v: Matmati, N, Hassan, B H, Ren, J, Shamssedine, A A, Jeong, E, Shariff, B, Snider, J, Rødkær, S V, Chen, G, Mohanty, B K, Zheng, W J, Obeid, L M, Røssel-Larsen, M, Færgeman, N J & Hannun, Y A 2020, ' Yeast Sphingolipid Phospholipase Gene ISC1 Regulates the Spindle Checkpoint by a CDC55-Dependent Mechanism ', Molecular and Cellular Biology, vol. 40, no. 12, e00340-19 . https://doi.org/10.1128/MCB.00340-19

Defects in the spindle assembly checkpoint (SAC) can lead to aneuploidy and cancer. Sphingolipids have important roles in many cellular functions, including cell cycle regulation and apoptosis. However, the specific mechanisms and functions of sphing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d11994cb137b6054010b72dfcea412a
https://findresearcher.sdu.dk:8443/ws/files/170551897/Molecular_and_Cellular_Biology_2020_Matmati_MCB.00340_19.full.pdf

Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1)

Autor: Bidyut K. Mohanty, Breege V. Howley, Buckley J. McCall, Toros Dincman, Annamarie C. Dalton, Ken Noguchi, Philip H. Howe

Publikováno v: The Journal of Biological Chemistry

Interleukin-like EMT inducer (ILEI, FAM3C) is a secreted factor that contributes to the epithelial-to-mesenchymal transition (EMT), a cell-biological process that confers metastatic properties to a tumor cell. However, very little is known about how

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93916e04c959c611cf49a2157f2694cf
https://doi.org/10.1074/jbc.ra118.003616

Yeast Sphingolipid Phospholipase Gene

Autor: Nabil, Matmati, Bachar H, Hassan, Jihui, Ren, Ashraf A, Shamssedine, Eunmi, Jeong, Baasil, Shariff, Justin, Snider, Steven V, Rødkær, Guocai, Chen, Bidyut K, Mohanty, W Jim, Zheng, Lina M, Obeid, Martin, Røssel-Larsen, Nils J, Færgeman, Yusuf A, Hannun

Publikováno v: Mol Cell Biol

Defects in the spindle assembly checkpoint (SAC) can lead to aneuploidy and cancer. Sphingolipids have important roles in many cellular functions, including cell cycle regulation and apoptosis. However, the specific mechanisms and functions of sphing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3aa6752c5af17f73f2dc28df8602e12a
https://pubmed.ncbi.nlm.nih.gov/32205408

Identification of C18:1-Phytoceramide as the Candidate Lipid Mediator for Hydroxyurea Resistance in Yeast

Autor: Yusuf A. Hannun, Shuqi Yan, Alessandra Metelli, Nabil Matmati, Kaushlendra Tripathi, Bidyut K. Mohanty

Publikováno v: Journal of Biological Chemistry. 288:17272-17284

Recent studies showed that deletion of ISC1, the yeast homologue of the mammalian neutral sphingomyelinase, resulted in an increased sensitivity to hydroxyurea (HU). This raised an intriguing question as to whether sphingolipids are involved in pathw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103d8d43562c429ffdc8cab0b065652b
https://doi.org/10.1074/jbc.m112.444802