Výsledky vyhledávání - "Bicyclo Compounds, Heterocyclic/metabolism"

Regulation of the endothelial plasminogen activator system by fluvastatin. Role of Rho family proteins, actin polymerisation and p38 MAP kinase

Autor: Egbert K. O. Kruithof, Richard J. Fish, Sylvie Dunoyer-Geindre

Publikováno v: Thrombosis and Haemostasis, Vol. 105, No 3 (2011) pp. 461-72
Thrombosis and haemostasis

SummaryStatins are cholesterol-lowering drugs that exert pleiotropic effects which include changes in the plasminogen activation (PA) system of endothelial cells (EC). It was the objective of this study to investigate the signal transduction pathways

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c6b20a22859c0a01f8e803afb81bd1
https://pubmed.ncbi.nlm.nih.gov/21174002

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[3H]A-585539 [(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]heptane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain

Autor: Daniel Bertrand, Anouk Marguerat, David J. Anderson, Eliane Tribollet, Bruce Surber, Murali Gopalakrishnan, Carol S. Surowy, Jia Du, William H. Bunnelle

Publikováno v: Journal of Pharmacology and Experimental Therapeutics, Vol. 324, No 1 (2008) pp. 179-187

Receptor binding was characterized for [(3)H](1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicycl o[2.2.1]heptane ([(3)H]A-585539), a selective high-affinity alpha7 nicotinic acetylcholine receptor (nAChR) agonist with rapid kinetics,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b14dfc8eac515f07f229a3f2f2d8f2
https://pubmed.ncbi.nlm.nih.gov/17959745

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High-resolution dissection of phagosome maturation reveals distinct membrane trafficking phases

Autor: Franz Bruckert, Thierry Soldati, Hans-Jörg Warnatz, Oliver Henschel, Daniel Gotthardt, Michael Schleicher

Publikováno v: Molecular Biology of the Cell : the Official Publication of the American Society for Cell Biology
Molecular Biology of the Cell, Vol. 13, No 10 (2002) pp. 3508-20

Molecular mechanisms of endocytosis in the genetically and biochemically tractable professional phagocyte Dictyostelium discoideum reveal a striking degree of similarity to higher eukaryotic cells. Pulse-chase feeding with latex beads allowed purific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7bd24e73d6b6f4733580d06befcd99
http://www.molbiolcell.org/cgi/content/full/13/10/3508

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