Nociceptor spontaneous activity is responsible for fragmenting non-rapid eye movement sleep in mouse models of neuropathic pain.

Autor: Alexandre C; Department of Neurosurgery, Neurosurgery Pain Research Institute, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Miracca G; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.; FM Kirby Neurobiology Center, Boston Children's Hospital and Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Holanda VD; Department of Neurosurgery, Neurosurgery Pain Research Institute, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Sharma A; Department of Neurosurgery, Neurosurgery Pain Research Institute, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Kourbanova K; Department of Neurosurgery, Neurosurgery Pain Research Institute, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Ferreira A; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.; FM Kirby Neurobiology Center, Boston Children's Hospital and Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Bicca MA; Department of Neurosurgery, Neurosurgery Pain Research Institute, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Zeng X; FM Kirby Neurobiology Center, Boston Children's Hospital and Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Nassar VA; Department of Neurosurgery, Neurosurgery Pain Research Institute, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Lee S; FM Kirby Neurobiology Center, Boston Children's Hospital and Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Kaur S; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA., Sarma SV; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA., Sacré P; Department of Electrical Engineering and Computer Science, School of Engineering, University of Liège, Liège, Belgium., Scammell TE; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA., Woolf CJ; FM Kirby Neurobiology Center, Boston Children's Hospital and Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Latremoliere A; Department of Neurosurgery, Neurosurgery Pain Research Institute, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2024 Apr 17; Vol. 16 (743), pp. eadg3036. Date of Electronic Publication: 2024 Apr 17.

Cannabinoid extract in microdoses ameliorates mnemonic and nonmnemonic Alzheimer's disease symptoms: a case report.

Autor: Ruver-Martins AC; Laboratório de Cannabis Medicinal e Ciência Psicodélica, Department of Medicine, Universidade Federal da Integração Latino-Americana, UNILA, Avenida Tarquínio Joslin dos Santos, 1000, Jardim Universitário I, Foz do Iguaçu, PR, Brazil., Bicca MA; Department of Neurosurgery and Neurosciences, Johns Hopkins University, Baltimore, MD, USA., de Araujo FS; Department of Chemistry, Universidade Federal do Paraná, Curitiba, PR, Brazil., de Noronha Sales Maia BHL; Department of Chemistry, Universidade Federal do Paraná, Curitiba, PR, Brazil., Pamplona FA; Laboratório de Cannabis Medicinal e Ciência Psicodélica, Department of Medicine, Universidade Federal da Integração Latino-Americana, UNILA, Avenida Tarquínio Joslin dos Santos, 1000, Jardim Universitário I, Foz do Iguaçu, PR, Brazil., da Silva EG; Laboratório de Cannabis Medicinal e Ciência Psicodélica, Department of Medicine, Universidade Federal da Integração Latino-Americana, UNILA, Avenida Tarquínio Joslin dos Santos, 1000, Jardim Universitário I, Foz do Iguaçu, PR, Brazil., Nascimento FP; Laboratório de Cannabis Medicinal e Ciência Psicodélica, Department of Medicine, Universidade Federal da Integração Latino-Americana, UNILA, Avenida Tarquínio Joslin dos Santos, 1000, Jardim Universitário I, Foz do Iguaçu, PR, Brazil. francisney.nascimento@unila.edu.br.

Publikováno v: Journal of medical case reports [J Med Case Rep] 2022 Jul 12; Vol. 16 (1), pp. 277. Date of Electronic Publication: 2022 Jul 12.

The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer's Disease.

Autor: Viola KL; Department of Neurobiology, Northwestern University, Evanston, IL, United States., Bicca MA; Department of Neurobiology, Northwestern University, Evanston, IL, United States., Bebenek AM; Illinois Mathematics and Science Academy, Aurora, IL, United States., Kranz DL; Department of Neurobiology, Northwestern University, Evanston, IL, United States., Nandwana V; Department of Materials Science and Engineering, Northwestern University, Evanston, IL, United States., Waters EA; Center for Advanced Molecular Imaging, Northwestern University, Evanston, IL, United States., Haney CR; Center for Advanced Molecular Imaging, Northwestern University, Evanston, IL, United States., Lee M; Department of Neurobiology, Northwestern University, Evanston, IL, United States., Gupta A; Illinois Mathematics and Science Academy, Aurora, IL, United States., Brahmbhatt Z; Illinois Mathematics and Science Academy, Aurora, IL, United States., Huang W; Department of Neurobiology, Northwestern University, Evanston, IL, United States., Chang TT; Small Animal Imaging Facility, Van Andel Research Institute, Grand Rapids, MI, United States.; Laboratory of Translational Imaging, Van Andel Research Institute, Grand Rapids, MI, United States., Peck A; Small Animal Imaging Facility, Van Andel Research Institute, Grand Rapids, MI, United States.; Laboratory of Translational Imaging, Van Andel Research Institute, Grand Rapids, MI, United States., Valdez C; Department of Neurobiology, Northwestern University, Evanston, IL, United States., Dravid VP; Illinois Mathematics and Science Academy, Aurora, IL, United States., Klein WL; Department of Neurobiology, Northwestern University, Evanston, IL, United States.; Department of Neurology, Northwestern University, Chicago, IL, United States.

Publikováno v: Frontiers in neuroscience [Front Neurosci] 2022 Jan 03; Vol. 15, pp. 768646. Date of Electronic Publication: 2022 Jan 03 (Print Publication: 2021).

Kinin Receptors Sensitize TRPV4 Channel and Induce Mechanical Hyperalgesia: Relevance to Paclitaxel-Induced Peripheral Neuropathy in Mice.

Autor: Costa R; Departamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis, SC, 88049-900, Brazil.; Programa de Pós-graduação de Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, RJ, Brazil., Bicca MA; Departamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis, SC, 88049-900, Brazil., Manjavachi MN; Departamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis, SC, 88049-900, Brazil., Segat GC; Departamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis, SC, 88049-900, Brazil., Dias FC; Programa de Pós-graduação de Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, RJ, Brazil., Fernandes ES; Programa de Pós-Graduação em Biologia Parasitária, Universidade Ceuma, São Luís, MA, Brazil.; Vascular Biology and Inflammation Section, Cardiovascular Division, King's College London, London, UK., Calixto JB; Departamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis, SC, 88049-900, Brazil. calixto@farmaco.ufsc.br.; Centro de Inovação e Ensaios Pré-clínicos (CIEnP), Av. Luiz Bouteux Piazza, 1302, Cachoeira do Bom Jesus, Florianópolis, SC, 88056-000, Brazil. calixto@farmaco.ufsc.br.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2018 Mar; Vol. 55 (3), pp. 2150-2161. Date of Electronic Publication: 2017 Mar 10.

Terpenoids, Cannabimimetic Ligands, beyond the Cannabis Plant.

Autor: Gonçalves ECD; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.; Graduate Program of Neuroscience, Center of Biological Sciences, Campus Florianópolis, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Brazil., Baldasso GM; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil., Bicca MA; Neurosurgery Department, Neurosurgery Pain Research institute, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA., Paes RS; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil., Capasso R; Department of Agricultural Sciences, University of Naples Federico II, 80,055 Portici, Italy., Dutra RC; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.; Graduate Program of Neuroscience, Center of Biological Sciences, Campus Florianópolis, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Brazil.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2020 Mar 29; Vol. 25 (7). Date of Electronic Publication: 2020 Mar 29.