Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Bibha Choudhary"'
Autor:
Meghana Manjunath, Febina Ravindran, Shivangi Sharma, Humaira Siddiqua, Sathees C. Raghavan, Bibha Choudhary
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6485 (2024)
Targeted cancer therapy aims to disrupt the functions of proteins that regulate cancer progression, mainly by using small molecule inhibitors (SMIs). SMIs exert their effect by modulating signalling pathways, organelle integrity, chromatin components
Externí odkaz:
https://doaj.org/article/04129bb706c244da86582eb5317cca4f
Autor:
Snehal Nirgude, Sagar Desai, Vartika Khanchandani, Vidhyavathy Nagarajan, Jayanti Thumsi, Bibha Choudhary
Publikováno v:
PeerJ, Vol 11, p e16033 (2023)
Genetic heterogeneity influences the prognosis and therapy of breast cancer. The cause of disease progression varies and can be addressed individually. To identify the mutations and their impact on disease progression at an individual level, we seque
Externí odkaz:
https://doaj.org/article/3302c19401284375a4b925ad56eac81b
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract ST08 and ST09 are potent curcumin derivatives with antiproliferative, apoptotic, and migrastatic properties. Both ST08 and ST09 exhibit in vitro and in vivo anticancer properties. As reported earlier, these derivatives were highly cytotoxic
Externí odkaz:
https://doaj.org/article/3c30a4e35f3b4668a0ab542bf4d6255d
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1629 (2023)
Multiple myeloma (MM) is a dyscrasia of plasma cells (PCs) characterized by abnormal immunoglobulin (Ig) production. The disease remains incurable due to a multitude of mutations and structural abnormalities in MM cells, coupled with a favorable micr
Externí odkaz:
https://doaj.org/article/cb4bbb1f4ac44d92993ab128c4aa1e8a
Autor:
Sagar Sanjiv Desai, Febina Ravindran, Amey Panchal, Nishit Ojha, Sachin Jadhav, Bibha Choudhary
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Acute leukemia is a heterogeneous disease with distinct genotypes and complex karyotypes leading to abnormal proliferation of hematopoietic cells. According to GLOBOCAN reports, Asia accounts for 48.6% of leukemia cases, and India repor
Externí odkaz:
https://doaj.org/article/f7a322950f8440aaa1e6bd45728571ce
Autor:
Anisha Mhatre, Jinsha Koroth, Meghana Manjunath, Sandeep Kumar S, Ramesh Gawari, Bibha Choudhary
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: In India, OVCa is women’s third most common and lethal cancer type, accounting for 6.7% of observed cancer incidences. The contribution of somatic mutations, aberrant expression of gene and splice forms in determining the cell fate, g
Externí odkaz:
https://doaj.org/article/1dd3a6a4dc384f20928c5309c38fec80
Autor:
Aditi Thakare, Chaitali Ghosh, Tejashwini Alalamath, Naveen Kumar, Himani Narang, Saurabh Whadgar, Kiran Paul, Shweta Shrotri, Sampath Kumar, M. Soumya, Raksha Rao, Mahul Chakraborty, Bibha Choudhary, Susanta K. Ghosh, Suresh Subramani, Sunita Swain, Subhashini Srinivasan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Anopheles stephensi is the most menacing malaria vector to watch for in newly urbanising parts of the world. Its fitness is reported to be a direct consequence of the vector adapting to laying eggs in over-head water tanks with street-side w
Externí odkaz:
https://doaj.org/article/8c343c2890d24031a0621c192012687f
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Ovarian cancers are among the fatal malignancies affecting women globally, mainly due to their metastatic and chemoresistant nature. In this study, we report a potent curcumin derivative ST09 effective against ovarian cancers. Prior in-vitro
Externí odkaz:
https://doaj.org/article/447685a3583f4c1880fa39144cac58e5
Autor:
Anju Sharma, Arigesavan Kaninathan, Sumedha Dahal, Susmita Kumari, Bibha Choudhary, Sathees C. Raghavan
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Increased infertility in humans is attributed to the increased use of environmental chemicals in the last several decades. Various studies have identified pesticides as one of the causes of reproductive toxicity. In a previous study, infertility was
Externí odkaz:
https://doaj.org/article/9c253d0ece7444feb3c30de32e17f750
Publikováno v:
Cancer Reports, Vol 5, Iss 10, Pp n/a-n/a (2022)
Abstract Background Curcumin is well known for its anticancer properties. Its cytotoxic activity has been documented in several cancer cell lines, including breast cancer. The pleiotropic activity of curcumin as an antioxidant, an antiangiogenic, ant
Externí odkaz:
https://doaj.org/article/37b1c6af0a794f04942121c81f1a2c52